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The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability
C González-Aguilera, C Tous, B Gómez-González, P Huertas, R Luna, ...
Molecular biology of the cell 19 (10), 4310-4318, 2008
1522008
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions
M Hohl, Y Kwon, SM Galván, X Xue, C Tous, A Aguilera, P Sung, ...
Nature structural & molecular biology 18 (10), 1124, 2011
912011
Genome-wide analysis of factors affecting transcription elongation and DNA repair: a new role for PAF and Ccr4-not in transcription-coupled repair
H Gaillard, C Tous, J Botet, C González-Aguilera, MJ Quintero, ...
PLoS Genet 5 (2), e1000364, 2009
812009
Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor
Á Peña, K Gewartowski, S Mroczek, J Cuéllar, A Szykowska, A Prokop, ...
The EMBO journal 31 (6), 1605-1616, 2012
752012
Impairment of transcription elongation by R-loops in vitro
C Tous, A Aguilera
Biochemical and biophysical research communications 360 (2), 428-432, 2007
742007
Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange
S Muñoz-Galván, C Tous, MG Blanco, EK Schwartz, KT Ehmsen, SC West, ...
Molecular and cellular biology 32 (9), 1592-1603, 2012
712012
A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors
C Tous, AG Rondón, M García‐Rubio, C González‐Aguilera, R Luna, ...
The EMBO journal 30 (10), 1953-1964, 2011
552011
Different physiological relevance of yeast THO/TREX subunits in gene expression and genome integrity
M García-Rubio, S Chávez, P Huertas, C Tous, S Jimeno, R Luna, ...
Molecular Genetics and Genomics 279 (2), 123-132, 2008
422008
Conditional Expression of RNase P in the CyanobacteriumSynechocystis sp. PCC6803 Allows Detection of Precursor RNAs: INSIGHT IN THE IN VIVO MATURATION PATHWAY OF TRANSFER AND …
C Tous, MA Vega-Palas, A Vioque
Journal of Biological Chemistry 276 (31), 29059-29066, 2001
412001
Nab2 functions in the metabolism of RNA driven by polymerases II and III
C González-Aguilera, C Tous, R Babiano, J de la Cruz, R Luna, ...
Molecular biology of the cell 22 (15), 2729-2740, 2011
392011
Gemcitabine plus sirolimus for relapsed and progressing osteosarcoma patients after standard chemotherapy: a multicenter, single-arm phase II trial of Spanish Group for …
J Martin-Broto, A Redondo, C Valverde, MA Vaz, J Mora, XG Del Muro, ...
Annals of Oncology 28 (12), 2994-2999, 2017
362017
Interdependence of the rad50 hook and globular domain functions
M Hohl, T Kochańczyk, C Tous, A Aguilera, A Krężel, JHJ Petrini
Molecular cell 57 (3), 479-491, 2015
342015
Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication
F Cortes-Ledesma, C Tous, A Aguilera
Nucleic acids research 35 (19), 6560-6570, 2007
322007
Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1)
M Perez, J Peinado-Serrano, JM Garcia-Heredia, I Felipe-Abrio, C Tous, ...
Oncotarget 7 (41), 67033, 2016
182016
New suppressors of THO mutations identify Thp3 (Ypr045c)-Csn12 as a protein complex involved in transcription elongation
S Jimeno, C Tous, ML García-Rubio, M Ranes, C González-Aguilera, ...
Molecular and Cellular Biology 31 (4), 674-685, 2011
152011
Control of the function of the transcription and repair factor TFIIH by the action of the cochaperone Ydj1
M Moriel-Carretero, C Tous, A Aguilera
Proceedings of the National Academy of Sciences 108 (37), 15300-15305, 2011
82011
Comparison of two types of surgical gastrostomies, open and laparoscopic in home enteral nutrition
C Tous, J Parejo Campos, R Oliva Rodríguez, P Serrano Aguayo, ...
Aula Médica Ediciones, 2012
72012
Phase II trial of gemcitabine plus rapamycin as second line in advanced osteosarcoma: A Spanish Group for Sarcoma Research (GEIS) Study.
J Martin Broto, A Redondo, CM Valverde, MA Vaz Salgado, J Mora, ...
Journal of Clinical Oncology 33 (15_suppl), 10530-10530, 2015
32015
Prognostic relevance of miRNA let-7e in localized intestinal GIST: A Spanish Group for Research on Sarcoma (GEIS) Study.
J Martin Broto, A Fernandez-Serra, J Duran, S Calabuig-Fariñas, ...
Journal of Clinical Oncology 33 (15_suppl), 10524-10524, 2015
12015
Impact of a brief educational intervention about nutrition and healthy lifestyles to school students given by a healthcare provider
RR Oliva, RM Tous, BB Gil, AG Longo, CJL Pereira, LPP García
Nutricion hospitalaria 28 (5), 1567, 2013
12013
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