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Clara Correia-Melo
Clara Correia-Melo
Leibniz Institute for Aging - Fritz Lipmann Institute (FLI)
Dirección de correo verificada de leibniz-fli.de
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Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
G Hewitt, D Jurk, FDM Marques, C Correia-Melo, T Hardy, A Gackowska, ...
Nature communications 3 (1), 708, 2012
8722012
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ...
Nature communications 5 (1), 4172, 2014
7642014
Mitochondria are required for pro‐ageing features of the senescent phenotype
C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ...
The EMBO journal 35 (7), 724-742, 2016
6242016
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence
R Anderson, A Lagnado, D Maggiorani, A Walaszczyk, E Dookun, ...
The EMBO journal 38 (5), e100492, 2019
3722019
Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
C Correia-Melo, G Hewitt, JF Passos
Longevity & healthspan 3, 1-9, 2014
1912014
Mitochondria: are they causal players in cellular senescence?
C Correia-Melo, JF Passos
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (11), 1373-1379, 2015
1782015
DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease
J Birch, RK Anderson, C Correia-Melo, D Jurk, G Hewitt, FM Marques, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015
1602015
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair
G Hewitt, B Carroll, R Sarallah, C Correia-Melo, M Ogrodnik, G Nelson, ...
Autophagy 12 (10), 1917-1930, 2016
1452016
A time-resolved proteomic and prognostic map of COVID-19
V Demichev, P Tober-Lau, O Lemke, T Nazarenko, C Thibeault, ...
Cell systems 12 (8), 780-794. e7, 2021
1412021
CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore‐microtubule dynamics to promote mitotic progression and fidelity
AL Manning, SF Bakhoum, S Maffini, C Correia‐Melo, H Maiato, ...
The EMBO journal 29 (20), 3531-3543, 2010
1402010
Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism
V Olin-Sandoval, JSL Yu, L Miller-Fleming, MT Alam, S Kamrad, ...
Nature 572 (7768), 249-253, 2019
1142019
Rapamycin improves healthspan but not inflammaging in nfκb1−/− mice
C Correia‐Melo, J Birch, E Fielder, D Rahmatika, J Taylor, J Chapman, ...
Aging cell 18 (1), e12882, 2019
682019
Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance
JSL Yu, C Correia-Melo, F Zorrilla, L Herrera-Dominguez, MY Wu, J Hartl, ...
Nature Microbiology, 1-14, 2022
582022
Depletion of mitochondria in mammalian cells through enforced mitophagy
C Correia-Melo, G Ichim, SWG Tait, JF Passos
nature protocols 12 (1), 183-194, 2017
522017
A proteomic survival predictor for COVID-19 patients in intensive care
V Demichev, P Tober-Lau, T Nazarenko, O Lemke, S Kaur Aulakh, ...
PLOS Digital Health 1 (1), e0000007, 2022
392022
Pyphe, a python toolbox for assessing microbial growth and cell viability in high-throughput colony screens
S Kamrad, M Rodríguez-López, C Cotobal, C Correia-Melo, M Ralser, ...
Elife 9, e55160, 2020
372020
Biochemical principles enabling metabolic cooperativity and phenotypic heterogeneity at the single cell level
K Campbell, L Herrera-Dominguez, C Correia-Melo, A Zelezniak, ...
Current Opinion in Systems Biology 8, 97-108, 2018
312018
Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance
S Kamrad, J Grossbach, M Rodríguez‐López, M Mülleder, SJ Townsend, ...
Molecular systems biology 16 (4), e9270, 2020
262020
Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan
C Correia-Melo, S Kamrad, R Tengölics, CB Messner, P Trebulle, ...
Cell 186 (1), 63-79. e21, 2023
242023
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat Commun 2: 4172
D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ...
Study showing the role of inflammation in impairing tissue regeneration and …, 2014
202014
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