| Site-specific integration by adeno-associated virus. RM Kotin, M Siniscalco, RJ Samulski, XD Zhu, L Hunter, CA Laughlin, ... Proceedings of the National Academy of Sciences 87 (6), 2211-2215, 1990 | 1403 | 1990 |
| Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system BL Davidson, CS Stein, JA Heth, I Martins, RM Kotin, TA Derksen, ... Proceedings of the National Academy of Sciences 97 (7), 3428-3432, 2000 | 865 | 2000 |
| RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model SQ Harper, PD Staber, X He, SL Eliason, IH Martins, Q Mao, L Yang, ... Proceedings of the National Academy of Sciences 102 (16), 5820-5825, 2005 | 850 | 2005 |
| RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia H Xia, Q Mao, SL Eliason, SQ Harper, IH Martins, HT Orr, HL Paulson, ... Nature medicine 10 (8), 816-820, 2004 | 824 | 2004 |
| Characterization of a preferred site on human chromosome 19q for integration of adeno‐associated virus DNA by non‐homologous recombination. RM Kotin, RM Linden, KI Berns The EMBO journal 11 (13), 5071-5078, 1992 | 703 | 1992 |
| Prospects for the use of adeno-associated virus as a vector for human gene therapy RM Kotin Human gene therapy 5 (7), 793-801, 1994 | 592 | 1994 |
| Insect cells as a factory to produce adeno-associated virus type 2 vectors M Urabe, C Ding, RM Kotin Human gene therapy 13 (16), 1935-1943, 2002 | 590 | 2002 |
| Cloning and characterization of adeno-associated virus type 5 JA Chiorini, F Kim, L Yang, RM Kotin Journal of virology 73 (2), 1309-1319, 1999 | 539 | 1999 |
| Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA. MD Weitzman, SR Kyöstiö, RM Kotin, RA Owens Proceedings of the National Academy of Sciences 91 (13), 5808-5812, 1994 | 539 | 1994 |
| Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter RM Kotin, JC Menninger, DC Ward, KI Berns Genomics 10 (3), 831-834, 1991 | 447 | 1991 |
| Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer J Zabner, M Seiler, R Walters, RM Kotin, W Fulgeras, BL Davidson, ... Journal of virology 74 (8), 3852-3858, 2000 | 404 | 2000 |
| Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles JA Chiorini, L Yang, Y Liu, B Safer, RM Kotin Journal of virology 71 (9), 6823-6833, 1997 | 382 | 1997 |
| A simplified baculovirus-AAV expression vector system coupled with one-step affinity purification yields high-titer rAAV stocks from insect cells RH Smith, JR Levy, RM Kotin Molecular Therapy 17 (11), 1888-1896, 2009 | 341 | 2009 |
| Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size GS Yang, M Schmidt, Z Yan, JD Lindbloom, TC Harding, BA Donahue, ... Journal of virology 76 (15), 7651-7660, 2002 | 258 | 2002 |
| Baculovirus: an insect-derived vector for diverse gene transfer applications KJ Airenne, YC Hu, TA Kost, RH Smith, RM Kotin, C Ono, Y Matsuura, ... Molecular Therapy 21 (4), 739-749, 2013 | 230 | 2013 |
| Production of adeno-associated virus in insect cells RM Kotin, M Urabe, CT Ding US Patent 6,723,551, 2004 | 219 | 2004 |
| Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep protein E Urcelay, P Ward, SM Wiener, B Safer, RM Kotin Journal of Virology 69 (4), 2038-2046, 1995 | 181 | 1995 |
| Organization of adeno-associated virus DNA in latently infected Detroit 6 cells RM Kotin, KI Berns Virology 170 (2), 460-467, 1989 | 178 | 1989 |
| Large-scale recombinant adeno-associated virus production RM Kotin Human molecular genetics 20 (R1), R2-R6, 2011 | 172 | 2011 |
| Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adeno-associated virus Rep AB Hickman, DR Ronning, RM Kotin, F Dyda Molecular cell 10 (2), 327-337, 2002 | 169 | 2002 |
