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Mark E Dudley
Mark E Dudley
CSO, Instil Bio
Verified email at instilbio.com
Title
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Cited by
Year
Cancer regression in patients after transfer of genetically engineered lymphocytes
RA Morgan, ME Dudley, JR Wunderlich, MS Hughes, JC Yang, ...
Science 314 (5796), 126-129, 2006
41122006
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
ME Dudley, JR Wunderlich, PF Robbins, JC Yang, P Hwu, ...
Science 298 (5594), 850-854, 2002
37272002
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
RA Morgan, JC Yang, M Kitano, ME Dudley, CM Laurencot, ...
Molecular therapy 18 (4), 843-851, 2010
28202010
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
SA Rosenberg, JC Yang, RM Sherry, US Kammula, MS Hughes, ...
Clinical cancer research 17 (13), 4550-4557, 2011
26082011
Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer
E Tran, S Turcotte, A Gros, PF Robbins, YC Lu, ME Dudley, ...
Science 344 (6184), 641-645, 2014
24172014
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
SA Rosenberg, JC Yang, DJ Schwartzentruber, P Hwu, FM Marincola, ...
Nature medicine 4 (3), 321-327, 1998
22351998
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
ME Dudley, JR Wunderlich, JC Yang, RM Sherry, SL Topalian, NP Restifo, ...
Journal of clinical oncology: official journal of the American Society of …, 2005
21182005
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
SA Rosenberg, NP Restifo, JC Yang, RA Morgan, ME Dudley
Nature Reviews Cancer 8 (4), 299-308, 2008
20862008
Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
M Ahmadzadeh, LA Johnson, B Heemskerk, JR Wunderlich, ME Dudley, ...
Blood, The Journal of the American Society of Hematology 114 (8), 1537-1544, 2009
20432009
Adoptive immunotherapy for cancer: harnessing the T cell response
NP Restifo, ME Dudley, SA Rosenberg
Nature Reviews Immunology 12 (4), 269-281, 2012
20272012
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
PF Robbins, RA Morgan, SA Feldman, JC Yang, RM Sherry, ME Dudley, ...
Journal of Clinical Oncology 29 (7), 917, 2011
19042011
Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric …
JN Kochenderfer, ME Dudley, SH Kassim, RPT Somerville, RO Carpenter, ...
Journal of clinical oncology 33 (6), 540, 2015
18962015
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
JN Kochenderfer, ME Dudley, SA Feldman, WH Wilson, DE Spaner, ...
Blood, The Journal of the American Society of Hematology 119 (12), 2709-2720, 2012
17832012
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
LA Johnson, RA Morgan, ME Dudley, L Cassard, JC Yang, MS Hughes, ...
Blood, The Journal of the American Society of Hematology 114 (3), 535-546, 2009
17162009
Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens
ME Dudley, JC Yang, R Sherry, MS Hughes, R Royal, U Kammula, ...
Journal of Clinical Oncology 26 (32), 5233, 2008
16392008
Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19
JN Kochenderfer, WH Wilson, JE Janik, ME Dudley, M Stetler-Stevenson, ...
Blood, The Journal of the American Society of Hematology 116 (20), 4099-4102, 2010
15952010
Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
RA Morgan, N Chinnasamy, D Abate-Daga, A Gros, PF Robbins, Z Zheng, ...
Journal of immunotherapy 36 (2), 133-151, 2013
12792013
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
MR Parkhurst, JC Yang, RC Langan, ME Dudley, DAN Nathan, ...
Molecular Therapy 19 (3), 620-626, 2011
11832011
PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors
A Gros, PF Robbins, X Yao, YF Li, S Turcotte, E Tran, JR Wunderlich, ...
The Journal of clinical investigation 124 (5), 2246-2259, 2014
10862014
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1–reactive T-cell receptor: long-term follow-up and correlates with response
PF Robbins, SH Kassim, TLN Tran, JS Crystal, RA Morgan, SA Feldman, ...
Clinical Cancer Research 21 (5), 1019-1027, 2015
8662015
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