Joshua D Hutcheson
Joshua D Hutcheson
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Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease
R Kramann, C Goettsch, J Wongboonsin, H Iwata, RK Schneider, ...
Cell stem cell 19 (5), 628-642, 2016
Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques
JD Hutcheson, C Goettsch, S Bertazzo, N Maldonado, JL Ruiz, W Goh, ...
Nature materials 15 (3), 335-343, 2016
Serotonin receptors and heart valve disease—it was meant 2B
JD Hutcheson, V Setola, BL Roth, WD Merryman
Pharmacology & therapeutics 132 (2), 146-157, 2011
Sortilin mediates vascular calcification via its recruitment into extracellular vesicles
C Goettsch, JD Hutcheson, M Aikawa, H Iwata, T Pham, A Nykjaer, ...
The Journal of clinical investigation 126 (4), 1323-1336, 2016
Potential drug targets for calcific aortic valve disease
JD Hutcheson, E Aikawa, WD Merryman
Nature Reviews Cardiology 11 (4), 218, 2014
An electrically active microneedle array for electroporation
SO Choi, YC Kim, JH Park, J Hutcheson, HS Gill, YK Yoon, MR Prausnitz, ...
Biomedical microdevices 12 (2), 263-273, 2010
5-HT2B antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation
JD Hutcheson, LM Ryzhova, V Setola, WD Merryman
Journal of molecular and cellular cardiology 53 (5), 707-714, 2012
Small entities with large impact: microcalcifications and atherosclerotic plaque vulnerability
JD Hutcheson, N Maldonado, E Aikawa
Current opinion in lipidology 25 (5), 327, 2014
Valvular interstitial cells suppress calcification of valvular endothelial cells
J Hjortnaes, K Shapero, C Goettsch, JD Hutcheson, J Keegan, J Kluin, ...
Atherosclerosis 242 (1), 251-260, 2015
MicroRNA in cardiovascular calcification: focus on targets and extracellular vesicle delivery mechanisms
C Goettsch, JD Hutcheson, E Aikawa
Circulation research 112 (7), 1073-1084, 2013
Cadherin-11 regulates cell–cell tension necessary for calcific nodule formation by valvular myofibroblasts
JD Hutcheson, J Chen, MK Sewell-Loftin, LM Ryzhova, CI Fisher, YR Su, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (1), 114-120, 2013
Spatiotemporal multi-omics mapping generates a molecular atlas of the aortic valve and reveals networks driving disease
F Schlotter, A Halu, S Goto, MC Blaser, SC Body, LH Lee, H Higashi, ...
Circulation 138 (4), 377-393, 2018
Changes in cell morphology due to plasma membrane wounding by acoustic cavitation
RK Schlicher, JD Hutcheson, H Radhakrishna, RP Apkarian, ...
Ultrasound in medicine & biology 36 (4), 677-692, 2010
Extracellular vesicles in cardiovascular calcification: expanding current paradigms
JB Krohn, JD Hutcheson, E Martínez‐Martínez, E Aikawa
The Journal of physiology 594 (11), 2895-2903, 2016
Directing valvular interstitial cell myofibroblast‐like differentiation in a hybrid hydrogel platform
J Hjortnaes, G Camci‐Unal, JD Hutcheson, SM Jung, FJ Schoen, J Kluin, ...
Advanced healthcare materials 4 (1), 121-130, 2015
18F-Fluoride Signal Amplification Identifies Microcalcifications Associated With Atherosclerotic Plaque Instability in Positron Emission Tomography/Computed …
MD Creager, T Hohl, JD Hutcheson, AJ Moss, F Schlotter, MC Blaser, ...
Circulation: Cardiovascular Imaging 12 (1), e007835, 2019
Extracellular vesicles as mediators of cardiovascular calcification
A Bakhshian Nik, JD Hutcheson, E Aikawa
Frontiers in cardiovascular medicine 4, 78, 2017
Saving cells from ultrasound-induced apoptosis: quantification of cell death and uptake following sonication and effects of targeted calcium chelation
JD Hutcheson, RK Schlicher, HK Hicks, MR Prausnitz
Ultrasound in medicine & biology 36 (6), 1008-1021, 2010
A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification
C Goettsch, JD Hutcheson, S Hagita, MA Rogers, MD Creager, T Pham, ...
Atherosclerosis 251, 109-118, 2016
Cardiovascular calcification: current controversies and novel concepts
JL Ruiz, JD Hutcheson, E Aikawa
Cardiovascular Pathology 24 (4), 207-212, 2015
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