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Tycho E.T. Mevissen, PhD
Tycho E.T. Mevissen, PhD
Harvard Medical School
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Mechanisms of deubiquitinase specificity and regulation
TET Mevissen, D Komander
Annu. Rev. Biochem 86 (1), 159-192, 2017
8562017
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
TET Mevissen, MK Hospenthal, PP Geurink, PR Elliott, M Akutsu, ...
Cell 154 (1), 169-184, 2013
5782013
Deubiquitinase-based analysis of ubiquitin chain architecture using Ubiquitin Chain Restriction (UbiCRest)
MK Hospenthal, TET Mevissen, D Komander
Nature protocols 10 (2), 349-361, 2015
2032015
Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase
N Birsa, R Norkett, T Wauer, TET Mevissen, HC Wu, T Foltynie, K Bhatia, ...
Journal of Biological Chemistry 289 (21), 14569-14582, 2014
2002014
Insights into ubiquitin chain architecture using Ub-clipping
KN Swatek, JL Usher, AF Kueck, C Gladkova, TET Mevissen, JN Pruneda, ...
Nature 572 (7770), 533-537, 2019
1782019
An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains
JDF Licchesi, J Mieszczanek, TET Mevissen, TJ Rutherford, M Akutsu, ...
Nature structural & molecular biology 19 (1), 62-71, 2012
1562012
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne
TET Mevissen, Y Kulathu, MPC Mulder, PP Geurink, SL Maslen, M Gersch, ...
Nature 538 (7625), 402-405, 2016
1492016
Regulation of A20 and other OTU deubiquitinases by reversible oxidation
Y Kulathu, FJ Garcia, TET Mevissen, M Busch, N Arnaudo, KS Carroll, ...
Nature communications 4 (1), 1569, 2013
1322013
The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II
Y van der Weegen, H Golan-Berman, TET Mevissen, K Apelt, ...
Nature Communications 11 (1), 1-16, 2020
1192020
Non-hydrolyzable diubiquitin probes reveal linkage-specific reactivity of deubiquitylating enzymes mediated by S2 pockets
D Flierman, R Ekkebus, PP Geurink, TET Mevissen, MK Hospenthal, ...
Cell chemical biology 23 (4), 472-482, 2016
1082016
Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages
M Min, TET Mevissen, M De Luca, D Komander, C Lindon
Molecular biology of the cell 26 (24), 4325-4332, 2015
742015
Development of diubiquitin‐based FRET probes to quantify ubiquitin linkage specificity of deubiquitinating enzymes
PP Geurink, BDM van Tol, D van Dalen, PJG Brundel, TET Mevissen, ...
ChemBioChem 17 (9), 816-820, 2016
522016
ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation
Y van der Weegen, K de Lint, D van den Heuvel, Y Nakazawa, ...
Nature Cell Biology 23 (6), 595-607, 2021
462021
Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease
FR Teixeira, SJ Randle, SP Patel, TET Mevissen, G Zenkeviciute, T Koide, ...
Biochemical Journal 473 (20), 3563-3580, 2016
462016
The E3 ubiquitin ligase SCF (Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway
V Spagnol, CAB Oliveira, SJ Randle, PMS Passos, CR Correia, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (1), 129754, 2021
142021
TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
TET Mevissen, AV Prasad, JC Walter
Cell Reports 42 (2), 2023
62023
The sequential and cooperative action of CSB, CSA and UVSSA targets the TFIIH complex to DNA damage-stalled RNA polymerase II
Y van der Weegen, HG Berman, TET Mevissen, K Apelt, ...
bioRxiv, 707216, 2019
52019
Ubiquitin chain analysis
TET Mevissen, MK Hospenthal, D Komander
US Patent 9,587,265, 2017
22017
Ubiquitin chain analysis
TET MEVISSEN, MK HOSPENTHAL, D Komander
12013
Cell-free Trim-Away reveals the mechanism of antibody-mediated protein degradation by TRIM21
TET Mevissen, AV Prasad, JC Walter
bioRxiv, 2022.07. 23.501259, 2022
2022
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