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Michael S.  Cohen
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RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ...
Journal of Biological Chemistry 282 (19), 14056-14064, 2007
8672007
Structural bioinformatics-based design of selective, irreversible kinase inhibitors
MS Cohen, C Zhang, KM Shokat, J Taunton
Science 308 (5726), 1318-1321, 2005
7132005
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ...
The EMBO journal 25 (12), 2781-2791, 2006
6782006
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
IM Serafimova, MA Pufall, S Krishnan, K Duda, MS Cohen, RL Maglathlin, ...
Nature chemical biology 8 (5), 471-476, 2012
5452012
Biosensor reveals multiple sources for mitochondrial NAD+
XA Cambronne, ML Stewart, DH Kim, AM Jones-Brunette, RK Morgan, ...
Science 352 (6292), 1474-1477, 2016
3522016
Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome
D Colak, N Zaninovic, MS Cohen, Z Rosenwaks, WY Yang, J Gerhardt, ...
Science 343 (6174), 1002-1005, 2014
3122014
Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition
M Cohen, M Georgiou, NL Stevenson, M Miodownik, B Baum
Developmental cell 19 (1), 78-89, 2010
2892010
Structural basis for potency and promiscuity in poly (ADP-ribose) polymerase (PARP) and tankyrase inhibitors
AG Thorsell, T Ekblad, T Karlberg, M Löw, AF Pinto, L Trésaugues, ...
Journal of medicinal chemistry 60 (4), 1262-1271, 2017
2882017
Insights into the biogenesis, function, and regulation of ADP-ribosylation
MS Cohen, P Chang
Nature chemical biology 14 (3), 236-243, 2018
2442018
RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells
U Doehn, C Hauge, SR Frank, CJ Jensen, K Duda, JV Nielsen, ...
Molecular cell 35 (4), 511-522, 2009
2392009
The association of femoral retroversion with slipped capital femoral epiphysis.
RH Gelberman, MS Cohen, BA Shaw, JR Kasser, PP Griffin, ...
JBJS 68 (7), 1000-1007, 1986
2301986
βTrCP-and Rsk1/2-mediated degradation of BimEL inhibits apoptosis
E Dehan, F Bassermann, D Guardavaccaro, G Vasiliver-Shamis, ...
Molecular cell 33 (1), 109-116, 2009
1892009
Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity
CD Heer, DJ Sanderson, LS Voth, YMO Alhammad, MS Schmidt, ...
Journal of Biological Chemistry 295 (52), 17986-17996, 2020
1842020
A clickable inhibitor reveals context-dependent autoactivation of p90 RSK
MS Cohen, H Hadjivassiliou, J Taunton
Nature chemical biology 3 (3), 156-160, 2007
1832007
ADP‐ribosyltransferases, an update on function and nomenclature
B Lüscher, I Ahel, M Altmeyer, A Ashworth, P Bai, P Chang, M Cohen, ...
The FEBS journal 289 (23), 7399-7410, 2022
1742022
FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway
S Kang, S Dong, TL Gu, A Guo, MS Cohen, S Lonial, HJ Khoury, ...
Cancer cell 12 (3), 201-214, 2007
1622007
A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis
NT Le, KS Heo, Y Takei, H Lee, CH Woo, E Chang, C McClain, C Hurley, ...
Circulation 127 (4), 486-499, 2013
1242013
Engineering the substrate specificity of ADP-ribosyltransferases for identifying direct protein targets
I Carter-O’Connell, H Jin, RK Morgan, LL David, MS Cohen
Journal of the American Chemical Society 136 (14), 5201-5204, 2014
1232014
ADP-ribosyl–binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication
R Abraham, D Hauer, RL McPherson, A Utt, IT Kirby, MS Cohen, A Merits, ...
Proceedings of the National Academy of Sciences 115 (44), E10457-E10466, 2018
1182018
APC/C-Cdh1-mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus
C Visintin, BN Tomson, R Rahal, J Paulson, M Cohen, J Taunton, A Amon, ...
Genes & development 22 (1), 79-90, 2008
1182008
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