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Raffaella Santoro
Raffaella Santoro
Dirección de correo verificada de dmmd.uzh.ch - Página principal
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The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription
R Santoro, J Li, I Grummt
Nature genetics 32 (3), 393-396, 2002
5012002
NoRC—a novel member of mammalian ISWI‐containing chromatin remodeling machines
R Strohner, A Nemeth, P Jansa, U Hofmann‐Rohrer, R Santoro, G Längst, ...
The EMBO journal, 2001
3822001
Intergenic transcripts regulate the epigenetic state of rRNA genes
C Mayer, KM Schmitz, J Li, I Grummt, R Santoro
Molecular cell 22 (3), 351-361, 2006
3802006
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors
D Zingg, J Debbache, SM Schaefer, E Tuncer, SC Frommel, P Cheng, ...
Nature communications 6 (1), 6051, 2015
3332015
The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription
Y Zhou, R Santoro, I Grummt
The EMBO journal 21 (17), 4632-4640, 2002
3022002
Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription
R Santoro, I Grummt
Molecular cell 8 (3), 719-725, 2001
2922001
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats
C Guetg, P Lienemann, V Sirri, I Grummt, D Hernandez‐Verdun, ...
The EMBO journal 29 (13), 2135-2146, 2010
2172010
Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation
R Santoro, I Grummt
Molecular and cellular biology 25 (7), 2539-2546, 2005
2152005
Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA
C Guetg, F Scheifele, F Rosenthal, MO Hottiger, R Santoro
Molecular cell 45 (6), 790-800, 2012
1692012
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
J Espada, E Ballestar, R Santoro, MF Fraga, A Villar-Garea, A Nemeth, ...
Nucleic acids research 35 (7), 2191-2198, 2007
1692007
DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells
SB Bachmann, SC Frommel, R Camicia, HC Winkler, R Santoro, ...
Molecular cancer 13, 1-24, 2014
1532014
Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes
S Erener, V Pétrilli, I Kassner, R Minotti, R Castillo, R Santoro, PO Hassa, ...
Molecular cell 46 (2), 200-211, 2012
1532012
lncRNA maturation to initiate heterochromatin formation in the nucleolus is required for exit from pluripotency in ESCs
N Savić, D Bär, S Leone, SC Frommel, FA Weber, E Vollenweider, ...
Cell stem cell 15 (6), 720-734, 2014
1442014
BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence
L Gu, SC Frommel, CC Oakes, R Simon, K Grupp, CY Gerig, D Bär, ...
Nature genetics 47 (1), 22-30, 2015
1432015
Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans
R Santoro, KM Schmitz, J Sandoval, I Grummt
EMBO reports 11 (1), 52-58, 2010
1382010
The chromatin remodeling complex NoRC controls replication timing of rRNA genes
J Li, R Santoro, K Koberna, I Grummt
The EMBO journal 24 (1), 120-127, 2005
1362005
EZH2-mediated primary cilium deconstruction drives metastatic melanoma formation
D Zingg, J Debbache, R Peña-Hernández, AT Antunes, SM Schaefer, ...
Cancer cell 34 (1), 69-84. e14, 2018
1142018
Formation of nuclear heterochromatin: the nucleolar point of view
C Guetg, R Santoro
Epigenetics 7 (8), 811-814, 2012
1062012
Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma
PF Cheng, O Shakhova, DS Widmer, OM Eichhoff, D Zingg, SC Frommel, ...
Genome biology 16, 1-16, 2015
1052015
Genome organization in and around the nucleolus
C Bersaglieri, R Santoro
Cells 8 (6), 579, 2019
1042019
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