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Chee-Huat Linus Eng
Chee-Huat Linus Eng
Dirección de correo verificada de caltech.edu
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Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+
CHL Eng, M Lawson, Q Zhu, R Dries, N Koulena, Y Takei, J Yun, ...
Nature 568 (7751), 235-239, 2019
12952019
Giotto: a toolbox for integrative analysis and visualization of spatial expression data
R Dries, Q Zhu, R Dong, CHL Eng, H Li, K Liu, Y Fu, T Zhao, A Sarkar, ...
Genome biology 22, 1-31, 2021
4402021
Dynamics and spatial genomics of the nascent transcriptome by intron seqFISH
S Shah, Y Takei, W Zhou, E Lubeck, J Yun, CHL Eng, N Koulena, ...
Cell 174 (2), 363-376. e16, 2018
2752018
Integrated spatial genomics reveals global architecture of single nuclei
Y Takei, J Yun, S Zheng, N Ollikainen, N Pierson, J White, S Shah, ...
Nature 590 (7845), 344-350, 2021
2482021
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis
T Lohoff, S Ghazanfar, A Missarova, N Koulena, N Pierson, JA Griffiths, ...
Nature biotechnology 40 (1), 74-85, 2022
1712022
Profiling the transcriptome with RNA SPOTs
CHL Eng, S Shah, J Thomassie, L Cai
Nature methods 14 (12), 1153-1155, 2017
1062017
Noncanonical amino acids to improve the pH response of pHLIP insertion at tumor acidity
JO Onyango, MS Chung, CH Eng, LM Klees, R Langenbacher, L Yao, ...
Angewandte Chemie International Edition 54 (12), 3658-3663, 2015
812015
Sequential probing of molecular targets based on pseudo-color barcodes with embedded error correction mechanism
L Cai, CH Eng, S Shah
US Patent App. 16/322,462, 2021
402021
Giotto, a pipeline for integrative analysis and visualization of single-cell spatial transcriptomic data
R Dries, Q Zhu, CHL Eng, A Sarkar, F Bao, RE George, N Pierson, L Cai, ...
BioRxiv, 701680, 2019
392019
Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis
T Lohoff, S Ghazanfar, A Missarova, N Koulena, N Pierson, JA Griffiths, ...
BioRxiv, 2020.11. 20.391896, 2020
232020
Multiplex labeling of molecules by sequential hybridization barcoding using probes with cleavable linkers
L Cai, CH Eng, E Lubeck
US Patent App. 15/225,820, 2016
162016
RNA seqFISH+ supplementary protocol
CHL Eng, L Cai
12019
Sensitive and multiplexed detection of nucleic acids and proteins for large scale serological testing
L Cai, CHL ENG, JJ Park, Y Yang, M Polonsky
US Patent App. 17/352,162, 2021
2021
Plus Ultra: Genome-Wide Spatial Transcriptomics with RNA SeqFISH+
CHL Eng
California Institute of Technology, 2021
2021
RNA seqFISH+ Supplementary Protocol
L Cai, CHL Eng
2019
Supplementary Protocol for RNA SPOTs
L Cai, CHL Eng, S Shah, J Thomassie
2017
pH low insertion peptide (pHLIP) as a drug carrier targeting acidic tumor microenvironments
L Klees, E Lichter, CH Eng, X Wang, C Shi, A Bodman, V Nazarenko, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
pHLIP-biosensor of tumor acidity with a built-in mechanism for transmembrane, cytoplasmic drug delivery
M An, L Klees, A Zhang, J Onyango, E Gordon, E Lichter, S Winge-Barnes, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016
2016
What is the Fate-Determining Step in pHLIP-Mediated Cargo Delivery?
M An, L Klees, A Zhang, JO Onyango, EA Gordon, CH Eng, ...
Biophysical Journal 110 (3), 80a, 2016
2016
Towards drug delivery via pHLIP insertion in the plasmamembrane of cancer cells at tumor extracellular pH
M An, J Onyango, M Chung, E Gordon, R Chandler, LCH Eng, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
2014
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Artículos 1–20