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Xiaodong Bu
Xiaodong Bu
Merck Research Lab
Dirección de correo verificada de merck.com
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Adsorbent screening for metal impurity removal in pharmaceutical process research
CJ Welch, J Albaneze-Walker, WR Leonard, M Biba, J DaSilva, ...
Organic process research & development 9 (2), 198-205, 2005
2662005
Oxidative impairment in scrapie‐infected mice is associated with brain metals perturbations and altered antioxidant activities
BS Wong, DR Brown, T Pan, M Whiteman, T Liu, X Bu, R Li, P Gambetti, ...
Journal of neurochemistry 79 (3), 689-698, 2001
1802001
Determination of halogens in organic compounds by high resolution inductively coupled plasma mass spectrometry (HR-ICP-MS)
X Bu, T Wang, G Hall
Journal of Analytical Atomic Spectrometry 18 (12), 1443-1451, 2003
1232003
Rapid catalyst identification for the synthesis of the pyrimidinone core of HIV integrase inhibitors
A Bellomo, N Celebi‐Olcum, X Bu, N Rivera, RT Ruck, CJ Welch, ...
Angewandte Chemie-International Edition 51 (28), 6912, 2012
772012
A kinase-cGAS cascade to synthesize a therapeutic STING activator
JA McIntosh, Z Liu, BM Andresen, NS Marzijarani, JC Moore, NM Marshall, ...
Nature 603 (7901), 439-444, 2022
622022
Macrocyclic glycopeptide chiral selectors bonded to core-shell particles enables enantiopurity analysis of the entire verubecestat synthetic route
CL Barhate, DA Lopez, AA Makarov, X Bu, WJ Morris, A Lekhal, ...
Journal of Chromatography A 1539, 87-92, 2018
532018
Screening binary systems of chelating agents combined with carbon or silica gel adsorbents: the development of a cost-effective method to remove palladium from pharmaceutical …
L Wang, L Green, Z Li, J McCabe Dunn, X Bu, CJ Welch, C Li, T Wang, ...
Organic Process Research & Development 15 (6), 1371-1376, 2011
462011
The emergence of low-cost compact mass spectrometry detectors for chromatographic analysis
X Bu, EL Regalado, SE Hamilton, CJ Welch
TrAC Trends in Analytical Chemistry 82, 22-34, 2016
432016
Rapid analysis of residual palladium in pharmaceutical development using a catalysis-based fluorometric method
X Bu, K Koide, EJ Carder, CJ Welch
Organic Process Research & Development 17 (1), 108-113, 2013
372013
Observations of rhodium‐containing reaction intermediates using HPLC with ICP‐MS and ESI‐MS detection
CJ Welch, Q Tu, T Wang, C Raab, P Wang, X Jia, X Bu, D Bykowski, ...
Advanced Synthesis & Catalysis 348 (7‐8), 821-825, 2006
342006
GC-FID method for high-throughput analysis of residual solvents in pharmaceutical drugs and intermediates
T Nowak, GC Graffius, Y Liu, N Wu, X Bu, X Gong, CJ Welch, ...
Green Chemistry 18 (13), 3732-3739, 2016
332016
Use of a miniature mass spectrometer to support pharmaceutical process chemistry
SE Hamilton, F Mattrey, X Bu, D Murray, B McCullough, CJ Welch
Organic Process Research & Development 18 (1), 103-108, 2014
322014
Determination of ruthenium in pharmaceutical compounds by graphite furnace atomic absorption spectroscopy
X Jia, T Wang, X Bu, Q Tu, S Spencer
Journal of pharmaceutical and biomedical analysis 41 (1), 43-47, 2006
272006
A competitive and reversible deactivation approach to catalysis-based quantitative assays
K Koide, MP Tracey, X Bu, J Jo, MJ Williams, CJ Welch
Nature Communications 7 (1), 10691, 2016
262016
9.02 High-Throughput Analysis for High-Throughput Experimentation in Organic Chemistry
W Schafer, X Bu, X Gong, LA Joyce, CJ Welch
Elsevier, 2014
262014
Generic gas chromatography-flame ionization detection method for quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates
GC Graffius, BM Jocher, D Zewge, HM Halsey, G Lee, F Bernardoni, X Bu, ...
Journal of Chromatography A 1518, 70-77, 2017
232017
Raman hyperspectral imaging with multivariate analysis for investigating enzyme immobilization
JP Smith, M Liu, ML Lauro, M Balasubramanian, JH Forstater, ST Grosser, ...
Analyst 145 (23), 7571-7581, 2020
202020
Online sensing of palladium in flowing streams
X Bu, M Williams, J Jo, K Koide, CJ Welch
Chemical communications 53 (4), 720-723, 2017
202017
Evaluation of a compact mass spectrometer for routine support of pharmaceutical chemistry
X Bu, J Yang, X Gong, CJ Welch
Journal of Pharmaceutical and Biomedical Analysis 94, 139-144, 2014
192014
Separation of triphenyl atropisomers of a pharmaceutical compound on a novel mixed mode stationary phase: a case study involving dynamic chromatography, dynamic NMR and …
X Bu, PJ Skrdla, PG Dormer, Y Bereznitski
Journal of Chromatography A 1217 (46), 7255-7264, 2010
192010
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