Derek Richard
Derek Richard
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Combination therapy with histone deacetylase inhibitors (HDACi) for the treatment of cancer: achieving the full therapeutic potential of HDACi
A Suraweera, KJ O’Byrne, DJ Richard
Frontiers in oncology 8, 92, 2018
Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature
MP Barr, SG Gray, AC Hoffmann, RA Hilger, J Thomale, JD O’Flaherty, ...
PloS one 8 (1), e54193, 2013
Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair
E Bolderson, DJ Richard, BBS Zhou, KK Khanna
Clinical Cancer Research 15 (20), 6314-6320, 2009
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability
DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ...
Nature 453 (7195), 677-681, 2008
Functions and therapeutic roles of exosomes in cancer
JA Tickner, AJ Urquhart, SA Stephenson, DJ Richard, KJ O’Byrne
Frontiers in oncology 4, 127, 2014
Circulating tumour cells, their role in metastasis and their clinical utility in lung cancer
JD O’Flaherty, S Gray, JJ O’Leary, FH Blackhall, KJ O’Byrne
Lung Cancer, 2011
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
E Bolderson, N Tomimatsu, DJ Richard, D Boucher, R Kumar, TK Pandita, ...
Nucleic acids research 38 (6), 1821-1831, 2010
Nucleophosmin: from structure and function to disease development
JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ...
BMC molecular biology 17 (1), 1-12, 2016
Identification of a BRCA1-mRNA splicing complex required for efficient DNA repair and maintenance of genomic stability
KI Savage, JJ Gorski, EM Barros, GW Irwin, L Manti, AJ Powell, ...
Molecular cell 54 (3), 445-459, 2014
Transcriptional regulation in response to oxygen and nitrate of the operons encoding the [NiFe] hydrogenases 1 and 2 of Escherichia coli
DJ Richard, G Sawers, F Sargent, L McWalter, DH Boxer
Microbiology 145 (10), 2903-2912, 1999
The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy
JD O’Flaherty, M Barr, D Fennell, D Richard, J Reynolds, J O’Leary, ...
Journal of thoracic oncology 7 (12), 1880-1890, 2012
Par4 is a coactivator for a splice isoform–specific transcriptional activation domain in WT1
DJ Richard, V Schumacher, B Royer-Pokora, SGE Roberts
Genes & development 15 (3), 328-339, 2001
The role of DNA repair pathways in cisplatin resistant lung cancer
S O’Grady, SP Finn, S Cuffe, DJ Richard, KJ O’Byrne, MP Barr
Cancer treatment reviews 40 (10), 1161-1170, 2014
BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability
KI Savage, KB Matchett, EM Barros, KM Cooper, GW Irwin, JJ Gorski, ...
Cancer research 74 (10), 2773-2784, 2014
Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis
DJ Richard, E Bolderson, KK Khanna
Critical reviews in biochemistry and molecular biology 44 (2-3), 98-116, 2009
HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response
Y Li, E Bolderson, R Kumar, PA Muniandy, Y Xue, DJ Richard, ...
Journal of Biological Chemistry 284 (35), 23525-23531, 2009
Structure of Hjc, a Holliday junction resolvase, from Sulfolobus solfataricus
CS Bond, M Kvaratskhelia, D Richard, MF White, WN Hunter
Proceedings of the National Academy of Sciences 98 (10), 5509-5514, 2001
Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising
C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ...
Frontiers in oncology 4, 86, 2014
INTS3 controls the hSSB1-mediated DNA damage response
JR Skaar, DJ Richard, A Saraf, A Toschi, E Bolderson, L Florens, ...
Journal of Cell Biology 187 (1), 25-32, 2009
hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex
DJ Richard, K Savage, E Bolderson, L Cubeddu, S So, M Ghita, DJ Chen, ...
Nucleic acids research 39 (5), 1692-1702, 2011
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