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Ching-Lin Hsieh
Ching-Lin Hsieh
Sanofi, Senior Principal Scientist
Dirección de correo verificada de cornell.edu
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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
D Wrapp, N Wang, KS Corbett, JA Goldsmith, CL Hsieh, O Abiona, ...
Science 367 (6483), 1260-1263, 2020
97112020
Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
CL Hsieh, JA Goldsmith, JM Schaub, AM DiVenere, HC Kuo, ...
Science 369 (6510), 1501-1505, 2020
10282020
Broad neutralization of SARS-related viruses by human monoclonal antibodies
AZ Wec, D Wrapp, AS Herbert, DP Maurer, D Haslwanter, M Sakharkar, ...
Science 369 (6504), 731-736, 2020
5412020
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates
BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ...
Science translational medicine 13 (593), eabf1906, 2021
3952021
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
PS Arunachalam, AC Walls, N Golden, C Atyeo, S Fischinger, C Li, P Aye, ...
Nature 594 (7862), 253-258, 2021
2722021
Prolonged evolution of the human B cell response to SARS-CoV-2 infection
M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ...
Science immunology 6 (56), eabg6916, 2021
1682021
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ...
Cell 184 (21), 5432-5447. e16, 2021
1432021
The SARS-CoV-2 spike reversibly samples an open-trimer conformation exposing novel epitopes
SM Costello, SR Shoemaker, HT Hobbs, AW Nguyen, CL Hsieh, ...
Nature Structural & Molecular Biology 29 (3), 229-238, 2022
842022
Stabilized coronavirus spike stem elicits a broadly protective antibody
CL Hsieh, AP Werner, SR Leist, LJ Stevens, E Falconer, JA Goldsmith, ...
Cell reports 37 (5), 2021
652021
Early cross-coronavirus reactive signatures of humoral immunity against COVID-19
P Kaplonek, C Wang, Y Bartsch, S Fischinger, MJ Gorman, K Bowman, ...
Science immunology 6 (64), eabj2901, 2021
622021
Novel mycobacteria antigen 85 complex binding motif on fibronectin
CJ Kuo, H Bell, CL Hsieh, CP Ptak, YF Chang
Journal of Biological Chemistry 287 (3), 1892-1902, 2012
582012
Proteomic characterization of outer membrane vesicles from gut mucosa-derived fusobacterium nucleatum
J Liu, CL Hsieh, O Gelincik, B Devolder, S Sei, S Zhang, SM Lipkin, ...
Journal of proteomics 195, 125-137, 2019
562019
Elastin, a novel extracellular matrix protein adhering to mycobacterial antigen 85 complex
CJ Kuo, CP Ptak, CL Hsieh, BL Akey, YF Chang
Journal of Biological Chemistry 288 (6), 3886-3896, 2013
482013
Expression and characterization of SARS-CoV-2 spike proteins
JM Schaub, CW Chou, HC Kuo, K Javanmardi, CL Hsieh, J Goldsmith, ...
Nature protocols 16 (11), 5339-5356, 2021
382021
Fine Mapping of the Interaction between C4b-Binding Protein and Outer Membrane Proteins LigA and LigB of Pathogenic Leptospira interrogans
LCD Breda, CL Hsieh, MM Castiblanco Valencia, LB da Silva, ...
PLoS neglected tropical diseases 9 (10), e0004192, 2015
362015
Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: Interim results of a randomised, placebo-controlled, phase …
P Pitisuttithum, V Luvira, S Lawpoolsri, S Muangnoicharoen, ...
EClinicalMedicine 45, 2022
352022
Dynamics of cleft closure of the GluA2 ligand-binding domain in the presence of full and partial agonists revealed by hydrogen-deuterium exchange
AH Ahmed, CP Ptak, MK Fenwick, CL Hsieh, GA Weiland, RE Oswald
Journal of Biological Chemistry 288 (38), 27658-27666, 2013
352013
Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
CL Hsieh, SA Rush, C Palomo, CW Chou, W Pickens, V Más, JS McLellan
Nature communications 13 (1), 1299, 2022
312022
Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition
KJ Kramer, NV Johnson, AR Shiakolas, N Suryadevara, S Periasamy, ...
Cell Reports 37 (1), 2021
242021
Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses
RP Silva, Y Huang, AW Nguyen, CL Hsieh, OS Olaluwoye, TS Kaoud, ...
Elife 12, 2023
232023
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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