| The'evolvability'of promiscuous protein functions A Aharoni, L Gaidukov, O Khersonsky, SMQ Gould, C Roodveldt, ... Nature genetics 37 (1), 73-76, 2005 | 1000 | 2005 |
| Enzyme promiscuity: evolutionary and mechanistic aspects O Khersonsky, C Roodveldt, DS Tawfik Current opinion in chemical biology 10 (5), 498-508, 2006 | 737 | 2006 |
| Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, ... Proceedings of the National Academy of Sciences 112 (16), E1994-E2003, 2015 | 536 | 2015 |
| The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase L Afriat, C Roodveldt, G Manco, DS Tawfik Biochemistry 45 (46), 13677-13686, 2006 | 300 | 2006 |
| High‐throughput Screens and Selections of Enzyme‐encoding Genes A Aharoni, C Roodveldt, AD Griffiths, DS Tawfik Enzyme Assays: High‐throughput Screening, Genetic Selection and Fingerprinting, 2005 | 266 | 2005 |
| Directed evolution of proteins for heterologous expression and stability C Roodveldt, A Aharoni, DS Tawfik Current opinion in structural biology 15 (1), 50-56, 2005 | 193 | 2005 |
| Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers B Mannini, R Cascella, M Zampagni, M van Waarde-Verhagen, S Meehan, ... Proceedings of the National Academy of Sciences 109 (31), 12479-12484, 2012 | 168 | 2012 |
| Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily C Roodveldt, DS Tawfik Biochemistry 44 (38), 12728-12736, 2005 | 149 | 2005 |
| Chaperone proteostasis in Parkinson's disease: Stabilization of the Hsp70/α‐synuclein complex by Hip C Roodveldt, CW Bertoncini, A Andersson, AT Van Der Goot, ST Hsu, ... The EMBO journal 28 (23), 3758-3770, 2009 | 130 | 2009 |
| Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state C Roodveldt, DS Tawfik Protein Engineering Design and Selection 18 (1), 51-58, 2005 | 121 | 2005 |
| Immunological features of α‐synuclein in Parkinson's disease C Roodveldt, J Christodoulou, CM Dobson Journal of cellular and molecular medicine 12 (5b), 1820-1829, 2008 | 117 | 2008 |
| Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, CC Lachaud, ... PloS one 8 (11), e79160, 2013 | 110 | 2013 |
| Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants C Roodveldt, A Labrador-Garrido, E Gonzalez-Rey, ... PloS one 5 (10), e13481, 2010 | 110 | 2010 |
| Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain FA Aprile, A Dhulesia, F Stengel, C Roodveldt, JLP Benesch, P Tortora, ... PLoS One 8 (6), e67961, 2013 | 90 | 2013 |
| The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction B Sot, A Rubio-Muñoz, A Leal-Quintero, J Martínez-Sabando, M Marcilla, ... Scientific reports 7 (1), 40859, 2017 | 56 | 2017 |
| The ‘omics’ of amyotrophic lateral sclerosis D Caballero-Hernandez, MG Toscano, M Cejudo-Guillen, ... Trends in molecular medicine 22 (1), 53-67, 2016 | 48 | 2016 |
| Extracellular TDP‐43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase‐3/IL‐18 signaling in microglia MM Leal‐Lasarte, JM Franco, A Labrador‐Garrido, D Pozo, C Roodveldt The FASEB Journal 31 (7), 2797-2816, 2017 | 47 | 2017 |
| A rationally designed six-residue swap generates comparability in the aggregation behavior of α-synuclein and β-synuclein C Roodveldt, A Andersson, EJ De Genst, A Labrador-Garrido, AK Buell, ... Biochemistry 51 (44), 8771-8778, 2012 | 31 | 2012 |
| Trypanosoma cruzi: identification of a galactose-binding protein that binds to cell surface of human erythrocytes and is involved in cell invasion by the parasite AM Silber, IS Marcipar, C Roodveldt, PC Meckert, R Laguens, ... Experimental parasitology 100 (4), 217-225, 2002 | 26 | 2002 |
| Immunization with α‐synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic Parkinsonism model J Villadiego, A Labrador‐Garrido, JM Franco, M Leal‐Lasarte, ... Glia 66 (1), 191-205, 2018 | 23 | 2018 |
