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Wint Wint Phoo
Wint Wint Phoo
Duke-NUS, Johnson and Johnson Satellite Center for Global Health Discovery
Dirección de correo verificada de duke-nus.edu.sg
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Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
WW Phoo, Y Li, Z Zhang, MY Lee, YR Loh, YB Tan, EY Ng, J Lescar, ...
Nature communications 7 (1), 13410, 2016
2182016
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication
Y Zhao, TS Soh, J Zheng, KWK Chan, WW Phoo, CC Lee, MYF Tay, ...
PLoS pathogens 11 (3), e1004682, 2015
2152015
Crystal structure of unlinked NS2B-NS3 protease from Zika virus
Z Zhang, Y Li, YR Loh, WW Phoo, AW Hung, CB Kang, D Luo
Science 354 (6319), 1597-1600, 2016
1792016
A subset of Kupffer cells regulates metabolism through the expression of CD36
C Blériot, E Barreby, G Dunsmore, R Ballaire, S Chakarov, X Ficht, ...
Immunity 54 (9), 2101-2116. e6, 2021
1152021
Structural dynamics of Zika virus NS2B-NS3 protease binding to dipeptide inhibitors
Y Li, Z Zhang, WW Phoo, YR Loh, W Wang, S Liu, MW Chen, AW Hung, ...
Structure 25 (8), 1242-1250. e3, 2017
1102017
Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor
Y Li, Z Zhang, WW Phoo, YR Loh, R Li, HY Yang, AE Jansson, J Hill, ...
Structure 26 (4), 555-564. e3, 2018
832018
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
CMD Swarbrick, C Basavannacharya, KWK Chan, SA Chan, D Singh, ...
Nucleic acids research 45 (22), 12904-12920, 2017
762017
Functional interplay among the flavivirus NS3 protease, helicase, and cofactors
K Li, WW Phoo, D Luo
Virologica Sinica 29, 74-85, 2014
702014
Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors
WW Phoo, Z Zhang, M Wirawan, EJC Chew, ABL Chew, J Kouretova, ...
Antiviral research 160, 17-24, 2018
582018
Structural characterization of the linked NS 2B‐NS 3 protease of Zika virus
Y Li, WW Phoo, YR Loh, Z Zhang, EY Ng, W Wang, TH Keller, D Luo, ...
FEBS letters 591 (15), 2338-2347, 2017
402017
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
DS Park, T Kozaki, SK Tiwari, M Moreira, A Khalilnezhad, F Torta, N Olivié, ...
Nature 623 (7986), 397-405, 2023
172023
Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3
WW Phoo, A El Sahili, ZZ Zhang, MW Chen, CW Liew, J Lescar, ...
Antiviral research 182, 104900, 2020
172020
Therapeutics for flaviviral infections
AM Bifani, KWK Chan, D Borrenberghs, MJA Tan, WW Phoo, S Watanabe, ...
Antiviral Research 210, 105517, 2023
102023
Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches
JP Quek, Z Ser, BLA Chew, X Li, L Wang, RM Sobota, D Luo, WW Phoo
Viruses 14 (7), 1440, 2022
62022
Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein
BLA Chew, AQ Ngoh, WW Phoo, KWK Chan, Z Ser, NK Tulsian, SS Lim, ...
bioRxiv, 2022.04. 06.487425, 2022
62022
Structural basis of Zika virus NS1 multimerization and human antibody recognition
BLA Chew, AQ Ngoh, WW Phoo, MJG Weng, HJ Sheng, KWK Chan, ...
npj Viruses 2 (1), 14, 2024
2024
A Broad-Spectrum Antiviral Targeting RNA Viruses.
CP Gwee, T Felicetti, KWK Chan, S Alonso, MJA Tan, WW Phoo, ...
Malaysian Journal of Medicine & Health Sciences 20, 2024
2024
Structural basis of Zika virus NS1 multimerization and human antibody recognition
D Luo, BLA Chew, AQ Ngoh, WW Phoo, MJG Weng, KWK Chan, YJ Tan, ...
2023
Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 upon binding to protease inhibitors
WW Phoo, AE Sahili, ZZ Zhang, MW Chen, CW Liew, J Lescar, ...
bioRxiv, 2020.01. 27.907089, 2020
2020
Structural and biochemical characterization of non-structural protein 3 from flavivirus
WW Phoo
2018
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Artículos 1–20