Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice P Bi, F Yue, A Karki, B Castro, SE Wirbisky, C Wang, A Durkes, BD Elzey, ... Journal of Experimental Medicine 213 (10), 2019-2037, 2016 | 80 | 2016 |
A single transcription factor is sufficient to induce and maintain secretory cell architecture HYG Lo, RU Jin, G Sibbel, D Liu, A Karki, MS Joens, BB Madison, ... Genes & development 31 (2), 154-171, 2017 | 75 | 2017 |
MIST1 links secretion and stress as both target and regulator of the unfolded protein response DA Hess, KM Strelau, A Karki, M Jiang, AC Azevedo-Pouly, AH Lee, ... Molecular and cellular biology 36 (23), 2931-2944, 2016 | 41 | 2016 |
Cotargeting polo-like kinase 1 and the Wnt/β-catenin signaling pathway in castration-resistant prostate cancer J Li, A Karki, KB Hodges, N Ahmad, A Zoubeidi, K Strebhardt, TL Ratliff, ... Molecular and cellular biology, 2015 | 40 | 2015 |
Plk1 inhibition enhances the efficacy of gemcitabine in human pancreatic cancer J Li, R Wang, PG Schweickert, A Karki, Y Yang, Y Kong, N Ahmad, ... Cell Cycle 15 (5), 711-719, 2016 | 38 | 2016 |
Silencing Mist1 gene expression is essential for recovery from acute pancreatitis A Karki, SE Humphrey, RE Steele, DA Hess, EJ Taparowsky, ... PloS one 10 (12), e0145724, 2015 | 35 | 2015 |
Targeting Plk1 sensitizes pancreatic cancer to immune checkpoint therapy Z Zhang, L Cheng, J Li, Q Qiao, A Karki, DB Allison, N Shaker, K Li, ... Cancer research 82 (19), 3532-3548, 2022 | 14 | 2022 |
Design considerations of an IL13Rα2 antibody–drug conjugate for diffuse intrinsic pontine glioma X Lian, D Kats, S Rasmussen, LR Martin, A Karki, C Keller, NE Berlow Acta neuropathologica communications 9 (1), 88, 2021 | 13 | 2021 |
DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling SS Kim, I Kycia, M Karski, RK Ma, EA Bordt, J Kwan, A Karki, E Winter, ... Plos one 17 (2), e0263829, 2022 | 8 | 2022 |
MDM4 expression in fibrolamellar hepatocellular carcinoma A Karki, J Putra, SS Kim, MJ Laquaglia, AR Perez‑Atayde, G Sadri‑Vakili, ... Oncology Reports, 2019 | 8 | 2019 |
Plexin-B2 and semaphorins do not drive rhabdomyosarcoma proliferation or migration A Karki, R Purohit, S Tosoni, N Bharathy, JE Michalek, S Chen, C Keller Sarcoma 2022, 2022 | 2 | 2022 |
Receptor-driven invasion profiles in diffuse intrinsic pontine glioma A Karki, NE Berlow, JA Kim, E Hulleman, Q Liu, JE Michalek, C Keller Neuro-oncology advances 3 (1), vdab039, 2021 | 2 | 2021 |
MDM4 expression is increased in fibrolamellar hepatocellular carcinoma with PRKACA-DNAJB1 fusion protein A Karki, J Putra, M LaQuaglia, A Perez-Atayde, K Vakili Cancer Research 78 (13_Supplement), 4150-4150, 2018 | 2 | 2018 |
A phase 1b/2 clinical study of onvansertib in combination with FOLFIRI/bevacizumab revealed a new role of PLK1 in regulating the hypoxia pathway in KRAS-mutant colorectal cancer M Ridinger, A Karki, RA Subramanian, E Samuelsz, D Yemane, R Kim, ... Cancer Research 84 (6_Supplement), 2031-2031, 2024 | | 2024 |
Cancer treatment using fgfr inhibitors and plk1 inhibitors M Ridinger, M Erlander, A Karki US Patent App. 18/046,648, 2023 | | 2023 |
TRANSCRIPT MODULATION OF LINC00473 AND CGA USING PKA-SPECIFIC siRNA IN CELL LINES EXPRESSING THE FIBROLAMELLAR HEPATOCELLULAR CARCINOMA-ASSOCIATED DNAJB1-PRKACA FUSION GENE S Kim, I Kycia, A Karki, Y Wu, D Bauer, K Vakili HEPATOLOGY 70, 474A-474A, 2019 | | 2019 |
Assessing DNA damage response pathway proteins ATM and p53 in fibrolamellar hepatocellular carcinoma with PRKACA-DNAJB1 fusion protein A Karki, K Vakili, AR Perez-Atayde CANCER RESEARCH 78 (19), 2018 | | 2018 |
Abstract B37: Assessing DNA damage response pathway proteins ATM and p53 in fibrolamellar hepatocellular carcinoma with PRKACA-DNAJB1 fusion protein A Karki, K Vakili, AR Perez-Atayde Cancer Research 78 (19_Supplement), B37-B37, 2018 | | 2018 |
Assessing the role of CREB in fibrolamellar hepatocellular carcinoma with PRKACA-DNAJB1 fusion protein A Karki, MJ LaQuaglia, AM Dios, G Sadri-Vakili, K Vakili Cancer Research 77 (13_Supplement), 3514-3514, 2017 | | 2017 |
Investigating the role of the basic helix-loop-helix transcription factor MIST1 in pancreatic diseases A Karki Purdue University, 2016 | | 2016 |