Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals M Shan, M Gentile, JR Yeiser, AC Walland, VU Bornstein, K Chen, B He, ... Science 342 (6157), 447-453, 2013 | 656 | 2013 |
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer V Rodilla, A Villanueva, A Obrador-Hevia, À Robert-Moreno, ... Proceedings of the National Academy of Sciences 106 (15), 6315-6320, 2009 | 444 | 2009 |
Phosphorylation by glycogen synthase kinase-3β down-regulates Notch activity, a link for Notch and Wnt pathways L Espinosa, J Inglés-Esteve, C Aguilera, A Bigas Journal of Biological Chemistry 278 (34), 32227-32235, 2003 | 419 | 2003 |
Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation LA Milner, A Bigas Blood, The Journal of the American Society of Hematology 93 (8), 2431-2448, 1999 | 414 | 1999 |
Blood development: hematopoietic stem cell dependence and independence E Dzierzak, A Bigas Cell stem cell 22 (5), 639-651, 2018 | 376 | 2018 |
RBPJκ-dependent signaling is essential for long-term maintenance of neural stem cells in the adult hippocampus O Ehm, C Göritz, M Covic, I Schäffner, TJ Schwarz, E Karaca, B Kempkes, ... Journal of Neuroscience 30 (41), 13794-13807, 2010 | 376 | 2010 |
RBPjκ-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells À Robert-Moreno, L Espinosa, JL de la Pompa, A Bigas Oxford University Press for The Company of Biologists Limited 132 (5), 1117-1126, 2005 | 351 | 2005 |
The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia L Espinosa, S Cathelin, T D'Altri, T Trimarchi, A Statnikov, J Guiu, ... Cancer cell 18 (3), 268-281, 2010 | 338 | 2010 |
Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines A Bigas, DIK Martin, LA Milner Molecular and cellular biology 18 (4), 2324-2333, 1998 | 288 | 1998 |
Inhibition of granulocytic differentiation by mNotch1 LA Milner, A Bigas, R Kopan, C Brashem-Stein, ID Bernstein, DIK Martin Proceedings of the National Academy of Sciences 93 (23), 13014-13019, 1996 | 245 | 1996 |
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1 À Robert‐Moreno, J Guiu, C Ruiz‐Herguido, ME López, J Inglés‐Esteve, ... The EMBO journal 27 (13), 1886-1895, 2008 | 233 | 2008 |
Hematopoietic stem cells: to be or Notch to be A Bigas, L Espinosa Blood, The Journal of the American Society of Hematology 119 (14), 3226-3235, 2012 | 222 | 2012 |
The association of Notch2 and NF-κB accelerates RANKL-induced osteoclastogenesis H Fukushima, A Nakao, F Okamoto, M Shin, H Kajiya, S Sakano, A Bigas, ... Molecular and cellular biology, 2008 | 200 | 2008 |
Notch signal strength controls cell fate in the haemogenic endothelium L Gama-Norton, E Ferrando, C Ruiz-Herguido, Z Liu, J Guiu, AB Islam, ... Nature communications 6 (1), 8510, 2015 | 171 | 2015 |
Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer V Fernandez-Majada, C Aguilera, A Villanueva, F Vilardell, ... Proceedings of the National Academy of Sciences 104 (1), 276-281, 2007 | 169 | 2007 |
Recruitment of IκBα to the hes1 promoter is associated with transcriptional repression C Aguilera, R Hoya-Arias, G Haegeman, L Espinosa, A Bigas Proceedings of the National Academy of Sciences 101 (47), 16537-16542, 2004 | 168 | 2004 |
Hematopoietic stem cell development requires transient Wnt/β-catenin activity C Ruiz-Herguido, J Guiu, T D'Altri, J Inglés-Esteve, E Dzierzak, ... Journal of Experimental Medicine 209 (8), 1457-1468, 2012 | 146 | 2012 |
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling J Guiu, R Shimizu, T D’Altri, ST Fraser, J Hatakeyama, EH Bresnick, ... Journal of Experimental Medicine 210 (1), 71-84, 2013 | 144 | 2013 |
IκBα and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFκB pathways L Espinosa, J Inglés-Esteve, A Robert-Moreno, A Bigas Molecular biology of the cell 14 (2), 491-502, 2003 | 133 | 2003 |
Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice J Farrés, J Martín-Caballero, C Martínez, JJ Lozano, L Llacuna, ... Blood, The Journal of the American Society of Hematology 122 (1), 44-54, 2013 | 130 | 2013 |