| Reducing endogenous tau ameliorates amyloid ß-induced deficits in an Alzheimer's disease mouse model ED Roberson, K Scearce-Levie, JJ Palop, F Yan, IH Cheng, T Wu, ... Science 316 (5825), 750-754, 2007 | 2314 | 2007 |
| Accelerating amyloid-β fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models IH Cheng, K Scearce-Levie, J Legleiter, JJ Palop, H Gerstein, N Bien-Ly, ... Journal of Biological Chemistry 282 (33), 23818-23828, 2007 | 501 | 2007 |
| Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease RO Sanchez-Mejia, JW Newman, S Toh, GQ Yu, Y Zhou, B Halabisky, ... Nature neuroscience 11 (11), 1311-1318, 2008 | 385 | 2008 |
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| Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients YS Fang, KJ Tsai, YJ Chang, P Kao, R Woods, PH Kuo, CC Wu, JY Liao, ... Nature communications 5 (1), 1-13, 2014 | 204 | 2014 |
| Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Aβ oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice WJ Meilandt, M Cisse, K Ho, T Wu, LA Esposito, K Scearce-Levie, ... Journal of Neuroscience 29 (7), 1977-1986, 2009 | 186 | 2009 |
| Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation IH Cheng, JJ Palop, LA Esposito, N Bien-Ly, F Yan, L Mucke Nature medicine 10 (11), 1190-1192, 2004 | 162 | 2004 |
| Collagen VI protects neurons against Aβ toxicity JS Cheng, DB Dubal, DH Kim, J Legleiter, IH Cheng, GQ Yu, I Tesseur, ... Nature neuroscience 12 (2), 119-121, 2009 | 155 | 2009 |
| Reactivity of apolipoprotein E4 and amyloid β peptide: lysosomal stability and neurodegeneration ZS Ji, K Müllendorff, IH Cheng, RD Miranda, Y Huang, RW Mahley Journal of Biological Chemistry 281 (5), 2683-2692, 2006 | 152 | 2006 |
| Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies WT Chen, CJ Hong, YT Lin, WH Chang, HT Huang, JY Liao, YJ Chang, ... PloS one 7 (4), e35807, 2012 | 139 | 2012 |
| Crude caffeine reduces memory impairment and amyloid β1–42 levels in an Alzheimer’s mouse model YF Chu, WH Chang, RM Black, JR Liu, P Sompol, Y Chen, H Wei, Q Zhao, ... Food chemistry 135 (3), 2095-2102, 2012 | 134 | 2012 |
| Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae SL Sawyer, IH Cheng, W Chai, BK Tye Journal of molecular biology 340 (2), 195-202, 2004 | 118 | 2004 |
| Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees YF Chu, PH Brown, BJ Lyle, Y Chen, RM Black, CE Williams, YC Lin, ... Journal of agricultural and food chemistry 57 (20), 9801-9808, 2009 | 116 | 2009 |
| Alterations of the neuroinflammatory markers IL-6 and TRAIL in Alzheimer's disease YY Wu, JL Hsu, HC Wang, SJ Wu, CJ Hong, IHJ Cheng Dementia and geriatric cognitive disorders extra 5 (3), 424-434, 2015 | 88 | 2015 |
| Acid-sensing ion channel-1a is not required for normal hippocampal LTP and spatial memory PY Wu, YY Huang, CC Chen, TT Hsu, YC Lin, JY Weng, TC Chien, ... Journal of Neuroscience 33 (5), 1828-1832, 2013 | 72 | 2013 |
| Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/phosphatidylinositol 3-kinase signaling pathway IH Cheng, YC Lin, E Hwang, HT Huang, WH Chang, YL Liu, CY Chao Neuroscience 183, 178-188, 2011 | 70 | 2011 |
| Plasma Aβ42 and total tau predict cognitive decline in amnestic mild cognitive impairment TB Chen, YJ Lee, SY Lin, JP Chen, CJ Hu, PN Wang, IH Cheng Scientific reports 9 (1), 13984, 2019 | 58 | 2019 |
| Antroquinonol lowers brain amyloid-β levels and improves spatial learning and memory in a transgenic mouse model of Alzheimer’s disease WH Chang, MC Chen, IH Cheng Scientific reports 5 (1), 15067, 2015 | 56 | 2015 |
| Bioactivities of crude caffeine: Antioxidant activity, cyclooxygenase-2 inhibition, and enhanced glucose uptake YF Chu, Y Chen, PH Brown, BJ Lyle, RM Black, IH Cheng, B Ou, RL Prior Food Chemistry 131 (2), 564-568, 2012 | 53 | 2012 |
| Potential blood biomarker for disease severity in the Taiwanese population with Alzheimer’s disease CW Huang, SJ Wang, SJ Wu, CC Yang, MW Huang, CH Lin, IH Cheng American Journal of Alzheimer's Disease & Other Dementias® 28 (1), 75-83, 2013 | 40 | 2013 |
