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Meghan Collins
Meghan Collins
Correu electrònic verificat a austin.utexas.edu
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Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials
TA Yap, N Daver, M Mahendra, J Zhang, C Kamiya-Matsuoka, ...
Nature medicine 29 (1), 115-126, 2023
892023
Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism
A Lodi, A Saha, X Lu, B Wang, E Sentandreu, M Collins, MG Kolonin, ...
NPJ precision oncology 1 (1), 18, 2017
872017
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia
N Baran, A Lodi, Y Dhungana, S Herbrich, M Collins, S Sweeney, ...
Nature communications 13 (1), 2801, 2022
292022
Gilteritinib Inhibits Glutamine Uptake and Utilization in FLT3-ITD–Positive AML
ME Zavorka Thomas, X Lu, Z Talebi, JY Jeon, DR Buelow, AA Gibson, ...
Molecular cancer therapeutics 20 (11), 2207-2217, 2021
282021
Novel strategy for untargeted chiral metabolomics using liquid chromatography-high resolution tandem mass spectrometry
R Pandey, M Collins, X Lu, SR Sweeney, J Chiou, A Lodi, S Tiziani
Analytical chemistry 93 (14), 5805-5814, 2021
222021
Identification of a synergistic combination of dimethylaminoparthenolide and shikonin alters metabolism and inhibits proliferation of pediatric precursor‐B cell acute …
SR Sweeney, M Collins, R Pandey, J Chiou, A Lodi, S Tiziani
Molecular Carcinogenesis 59 (4), 399-411, 2020
222020
Predicting and quantifying antagonistic effects of natural compounds given with chemotherapeutic agents: Applications for high-throughput screening
GL Hackman, M Collins, X Lu, A Lodi, J DiGiovanni, S Tiziani
Cancers 12 (12), 3714, 2020
162020
The combined treatment with the FLT3-inhibitor AC220 and the complex I inhibitor IACS-010759 synergistically depletes Wt-and FLT3-mutated acute myeloid leukemia cells
X Lu, L Han, J Busquets, M Collins, A Lodi, JR Marszalek, M Konopleva, ...
Frontiers in Oncology 11, 686765, 2021
122021
The low molecular weight protein tyrosine phosphatase promotes adipogenesis and subcutaneous adipocyte hypertrophy
SM Stanford, M Collins, MA Diaz, ZJ Holmes, P Gries, MR Bliss, A Lodi, ...
Journal of cellular physiology 236 (9), 6630-6642, 2021
82021
Metabolomics-based phenotypic screens for evaluation of drug synergy via direct-infusion mass spectrometry
X Lu, GL Hackman, A Saha, AS Rathore, M Collins, C Friedman, SS Yi, ...
Iscience 25 (5), 2022
62022
Targeting Oxidative Phosphorylation with a Mitochondrial Complex I Inhibitor is limited by Mechanism-based Toxicity
M Konopleva, T Yap, N Daver, M Mahendra, J Zhang, ...
32022
Isolation of Synergistic Natural Products Targeting Metabolic Dysfunction in Pediatric Pre‐B Cell Acute Lymphoblastic Leukemia Using High‐Throughput Screening and Metabolomics
ME Collins, SR Sweeney, S Tiziani
The FASEB Journal 33 (S1), lb225-lb225, 2019
12019
Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses
M Konopleva, C DiNardo, T Bhagat, N Baran, A Lodi, K Saxena, T Cai, ...
Research Square, 2023
2023
Lipophagy As a Mechanism of Resistance in T-ALL Following Energetic Crisis Induced By Oxphos/MCT1 Blockade: Strategies to Eradicate Residual Disease
N Baran, S Patel, CL Ramage, A Lodi, JE Ortiz, Y Dhungana, M Collins, ...
Blood 140 (Supplement 1), 8831-8832, 2022
2022
Accumulation of Intracellular L-Lactate and Irreversible Disruption of Mitochondrial Membrane Potential upon Dual Inhibition of Oxphos and Lactate Transporter MCT-1 Induce …
N Baran, S Patel, A Lodi, JE Ortiz, Y Dhungana, M Collins, A Skwarska, ...
Blood 138, 680, 2021
2021
Gilteritinib Inhibits Acute Myeloid Leukemia Growth via Reduction in Glutamine Uptake and Utilization
MZ Thomas, JY Jeon, S Shabana, D Buelow, A Gibson, J Anderson, ...
The FASEB Journal 34 (S1), 1-1, 2020
2020
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