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Samuel Fountain
Samuel Fountain
Verified email at uea.ac.uk
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Update of P2X receptor properties and their pharmacology: IUPHAR Review 30
P Illes, CE Müller, KA Jacobson, T Grutter, A Nicke, SJ Fountain, ...
British Journal of Pharmacology 178 (3), 489-514, 2021
2072021
An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum
SJ Fountain, K Parkinson, MT Young, L Cao, CRL Thompson, RA North
Nature 448 (7150), 200-203, 2007
1732007
Human TRPC5 channel activated by a multiplicity of signals in a single cell
F Zeng, SZ Xu, PK Jackson, D McHugh, B Kumar, SJ Fountain, DJ Beech
The Journal of physiology 559 (3), 739-750, 2004
1552004
P2X4 receptor function in the nervous system and current breakthroughs in pharmacology
L Stokes, JA Layhadi, L Bibic, K Dhuna, SJ Fountain
Frontiers in pharmacology 8, 291, 2017
1322017
An evolutionary history of P2X receptors
SJ Fountain, G Burnstock
Purinergic signalling 5, 269-272, 2009
1022009
Permeation properties of a P2X receptor in the green algae Ostreococcus tauri
SJ Fountain, L Cao, MT Young, RA North
Journal of Biological Chemistry 283 (22), 15122-15126, 2008
982008
ATP evokes Ca2+ responses and CXCL5 secretion via P2X4 receptor activation in human monocyte-derived macrophages
JA Layhadi, J Turner, D Crossman, SJ Fountain
The Journal of Immunology 200 (3), 1159-1168, 2018
832018
A C-terminal lysine that controls human P2X4 receptor desensitization
SJ Fountain, RA North
Journal of Biological Chemistry 281 (22), 15044-15049, 2006
812006
Action of MK‐7264 (gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation
D Richards, JR Gever, AP Ford, SJ Fountain
British journal of pharmacology 176 (13), 2279-2291, 2019
692019
Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308
L Cao, MT Young, HE Broomhead, SJ Fountain, RA North
Journal of Neuroscience 27 (47), 12916-12923, 2007
682007
Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes
V Sivaramakrishnan, S Bidula, H Campwala, D Katikaneni, SJ Fountain
Journal of cell science 125 (19), 4567-4575, 2012
672012
Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopy
MT Young, JA Fisher, SJ Fountain, RC Ford, RA North, BS Khakh
Journal of biological chemistry 283 (38), 26241-26251, 2008
612008
P2X4 Receptor-Dependent Ca2+ Influx in Model Human Monocytes and Macrophages
JA Layhadi, SJ Fountain
International journal of molecular sciences 18 (11), 2261, 2017
522017
Primitive ATP-activated P2X receptors: discovery, function and pharmacology
SJ Fountain
Frontiers in cellular neuroscience 7, 247, 2013
492013
Functional up‐regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle
SJ Fountain, A Cheong, R Flemming, L Mair, A Sivaprasadarao, ...
The Journal of Physiology 556 (1), 29-42, 2004
472004
Kv1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress
SJ Fountain, A Cheong, J Li, NY Dondas, F Zeng, IC Wood, DJ Beech
American Journal of Physiology-Heart and Circulatory Physiology 293 (5 …, 2007
402007
P2Y12 receptor modulation of ADP‐evoked intracellular Ca2+ signalling in THP‐1 human monocytic cells
JJ Micklewright, JA Layhadi, SJ Fountain
British Journal of Pharmacology 175 (12), 2483-2491, 2018
372018
P2Y6 receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells
H Campwala, DW Sexton, DC Crossman, SJ Fountain
Journal of cell science 127 (22), 4964-4973, 2014
372014
Fluvastatin suppresses native and recombinant human P2X4 receptor function
J Li, SJ Fountain
Purinergic signalling 8, 311-316, 2012
322012
ATP-Evoked Intracellular Ca2+ Responses in M-CSF Differentiated Human Monocyte-Derived Macrophage are Mediated by P2X4 and P2Y11 Receptor Activation
JA Layhadi, SJ Fountain
International journal of molecular sciences 20 (20), 5113, 2019
252019
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