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Shih Chieh Chang Jeff
Shih Chieh Chang Jeff
Unknown affiliation
Verified email at merck.com
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Cited by
Year
Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics
Y Sun, SY Lau, ZW Lim, SC Chang, F Ghadessy, A Partridge, A Miserez
Nature Chemistry 14 (3), 274-283, 2022
1372022
Kv1. 3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases
S Chhabra, SC Chang, HM Nguyen, R Huq, MR Tanner, LM Londono, ...
The FASEB Journal 28 (9), 3952, 2014
882014
bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA)
S Lim, R Khoo, KM Peh, J Teo, SC Chang, S Ng, GL Beilhartz, RA Melnyk, ...
Proceedings of the National Academy of Sciences 117 (11), 5791-5800, 2020
792020
Development of highly selective Kv1. 3-blocking peptides based on the sea anemone peptide ShK
MW Pennington, SC Chang, S Chauhan, R Huq, RB Tajhya, S Chhabra, ...
Marine Drugs 13 (1), 529-542, 2015
712015
A potent and selective peptide blocker of the Kv1. 3 channel: prediction from free-energy simulations and experimental confirmation
MH Rashid, G Heinzelmann, R Huq, RB Tajhya, SC Chang, S Chhabra, ...
PloS one 8 (11), e78712, 2013
692013
CD4+ T Cells Mediate the Development of Liver Fibrosis in High Fat Diet-Induced NAFLD in Humanized Mice
Z Her, JHL Tan, YS Lim, SY Tan, XY Chan, WWS Tan, M Liu, KSM Yong, ...
Frontiers in immunology 11, 580968, 2020
612020
N‐terminally extended analogues of the K+ channel toxin from Stichodactyla helianthus as potent and selective blockers of the voltage‐gated potassium channel …
SC Chang, R Huq, S Chhabra, C Beeton, MW Pennington, BJ Smith, ...
The FEBS journal 282 (12), 2247-2259, 2015
382015
Expression and isotopic labelling of the potassium channel blocker ShK toxin as a thioredoxin fusion protein in bacteria
SC Chang, CA Galea, EWW Leung, RB Tajhya, C Beeton, ...
Toxicon 60 (5), 840-850, 2012
322012
Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin
ST Ong, S Bajaj, MR Tanner, SC Chang, B Krishnarjuna, XR Ng, ...
ACS pharmacology & translational science 3 (4), 720-736, 2020
192020
Conformational flexibility in the binding surface of the potassium channel blocker ShK
I Sher, SC Chang, Y Li, S Chhabra, AG Palmer III, RS Norton, JH Chill
ChemBioChem 15 (16), 2402-2410, 2014
122014
Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
SC Chang, P Gopal, S Lim, X Wei, A Chandramohan, R Mangadu, ...
Cell Chemical Biology 29 (11), 1601-1615. e7, 2022
92022
ShK toxin: history, structure and therapeutic applications for autoimmune diseases
SC Chang, S Bajaj, KG Chandy
WikiJournal of Science 1 (1), 1-13, 2018
82018
STUB1 is an intracellular checkpoint for interferon gamma sensing
S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, ...
Scientific Reports 12 (1), 14087, 2022
62022
Kv1. 3-Blocking Peptides from Parasitic Worms Exhibit Immunomodulatory Function
HM Nguyen, S Chhabra, SC Chang, RU Huq, MR Tanner, LM Londono, ...
Biophysical Journal 106 (2), 739a, 2014
22014
Novel potassium channel blockers for the treatment of multiple sclerosis and other autoimmune diseases
SC Chang
Monash University, 2014
12014
Potassium channel blockers and use thereof in the treatment of autoimmune diseases
RS Norton, SC Chang, MW Pennington, C Beeton, BJ Smith
US Patent 10,246,496, 2019
2019
Biophysical and structural characterization of a putative K+ channel from Mycobacterium tuberculosis-a potential drug target
S Bajaj, J Ng Jun Heng, KG Chandy, A El Sahili, J Lescar, SC Chang, ...
2018
Cover Picture: Conformational Flexibility in the Binding Surface of the Potassium Channel Blocker ShK (ChemBioChem 16/2014)
I Sher, SC Chang, Y Li, S Chhabra, AG Palmer III, RS Norton, JH Chill
ChemBioChem 15 (16), 2317-2317, 2014
2014
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