Regulation of IL-1β–induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways CC Scholz, MAS Cavadas, MM Tambuwala, E Hams, J Rodríguez, ... Proceedings of the National Academy of Sciences 110 (46), 18490-18495, 2013 | 183 | 2013 |
ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma–lamin A complexes J Rodríguez, F Calvo, JM González, B Casar, V Andrés, P Crespo Journal of Cell Biology 191 (5), 967-979, 2010 | 102 | 2010 |
Substrate-trapped interactors of PHD3 and FIH cluster in distinct signaling pathways J Rodriguez, R Pilkington, AG Munoz, LK Nguyen, N Rauch, S Kennedy, ... Cell reports 14 (11), 2745-2760, 2016 | 95 | 2016 |
FIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1 CC Scholz, J Rodriguez, C Pickel, S Burr, J Fabrizio, KA Nolan, ... PLoS biology 14 (1), e1002347, 2016 | 94 | 2016 |
Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure MP Smith, EJ Rowling, Z Miskolczi, J Ferguson, L Spoerri, NK Haass, ... EMBO molecular medicine 9 (8), 1011-1029, 2017 | 71 | 2017 |
PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359 J Rodriguez, A Herrero, S Li, N Rauch, A Quintanilla, K Wynne, A Krstic, ... Cell reports 24 (5), 1316-1329, 2018 | 65 | 2018 |
Working Without Kinase Activity: Phosphotransfer-Independent Functions of Extracellular Signal–Regulated Kinases J Rodríguez, P Crespo Science signaling 4 (196), re3-re3, 2011 | 64 | 2011 |
Mxi2 promotes stimulus‐independent ERK nuclear translocation B Casar, V Sanz‐Moreno, MN Yazicioglu, J Rodríguez, MT Berciano, ... The EMBO journal 26 (3), 635-646, 2007 | 62 | 2007 |
CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion AJ Farrugia, J Rodríguez, JL Orgaz, M Lucas, V Sanz-Moreno, F Calvo Journal of Cell Biology 219 (9), 2020 | 49 | 2020 |
An integrated global analysis of compartmentalized HRAS signaling T Santra, A Herrero, J Rodriguez, A Von Kriegsheim, LF Iglesias-Martinez, ... Cell reports 26 (11), 3100-3115. e7, 2019 | 41 | 2019 |
Carbon dioxide-dependent regulation of NF-κB family members RelB and p100 gives molecular insight into CO2-dependent immune regulation CE Keogh, CC Scholz, J Rodriguez, AC Selfridge, A von Kriegsheim, ... Journal of Biological Chemistry 292 (27), 11561-11571, 2017 | 38 | 2017 |
NADPH oxidase-derived H2O2 subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA LA Alvarez, L Kovačič, J Rodríguez, JH Gosemann, M Kubica, ... Proceedings of the National Academy of Sciences 113 (37), 10406-10411, 2016 | 37 | 2016 |
Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity A von Thun, C Preisinger, O Rath, JP Schwarz, C Ward, N Monsefi, ... Molecular and cellular biology 33 (22), 4526-4537, 2013 | 37 | 2013 |
A new ER-specific photosensitizer unravels 1 O 2-driven protein oxidation and inhibition of deubiquitinases as a generic mechanism for cancer PDT A Pinto, Y Mace, F Drouet, E Bony, R Boidot, N Draoui, I Lobysheva, ... Oncogene 35 (30), 3976-3985, 2016 | 36 | 2016 |
Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer G Zurlo, X Liu, M Takada, C Fan, JM Simon, TS Ptacek, J Rodriguez, ... Nature Communications 10 (1), 5177, 2019 | 32 | 2019 |
Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner SF Fitzpatrick, Z Fábián, B Schaible, CR Lenihan, T Schwarzl, ... Biochemical and biophysical research communications 474 (3), 579-586, 2016 | 30 | 2016 |
Hypoxia Reduces the Pathogenicity of Pseudomonas aeruginosa by Decreasing the Expression of Multiple Virulence Factors B Schaible, J Rodriguez, A Garcia, A von Kriegsheim, S McClean, ... The Journal of Infectious Diseases 215 (9), 1459-1467, 2017 | 25 | 2017 |
Growth cone localization of the mRNA encoding the chromatin regulator HMGN5 modulates neurite outgrowth F Moretti, C Rolando, M Winker, R Ivanek, J Rodriguez, A Von Kriegsheim, ... Molecular and cellular biology 35 (11), 2035-2050, 2015 | 24 | 2015 |
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness H Holme, A Gulati, R Brough, EDG Fleuren, I Bajrami, J Campbell, ... Scientific reports 8 (1), 10614, 2018 | 19 | 2018 |
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance S Li, J Rodriguez, W Li, P Bullova, SM Fell, O Surova, I Westerlund, ... Proceedings of the National Academy of Sciences 116 (34), 16997-17006, 2019 | 18 | 2019 |