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Christopher Swale
Christopher Swale
INSERM
Dirección de correo verificada de univ-grenoble-alpes.fr
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Mutational and metal binding analysis of the endonuclease domain of the influenza virus polymerase PA subunit
T Crépin, A Dias, A Palencia, C Swale, S Cusack, RWH Ruigrok
Journal of virology 84 (18), 9096-9104, 2010
1162010
A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment
DC Farhat, C Swale, C Dard, D Cannella, P Ortet, M Barakat, ...
Nature microbiology 5 (4), 570-583, 2020
90*2020
Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection
C Swale, A Bougdour, A Gnahoui-David, J Tottey, S Georgeault, ...
Science translational medicine 11 (517), eaax7161, 2019
482019
Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza
A Monod, C Swale, B Tarus, A Tissot, B Delmas, RWH Ruigrok, T Crépin, ...
Expert opinion on drug discovery 10 (4), 345-371, 2015
372015
Structural characterization of recombinant IAV polymerase reveals a stable complex between viral PA-PB1 heterodimer and host RanBP5
C Swale, A Monod, L Tengo, A Labaronne, F Garzoni, JM Bourhis, ...
Scientific reports 6 (1), 24727, 2016
312016
Target identification of an antimalarial oxaborole identifies AN13762 as an alternative chemotype for targeting CPSF3 in apicomplexan parasites
V Bellini, C Swale, MP Brenier-Pinchart, T Pezier, S Georgeault, F Laurent, ...
IScience 23 (12), 2020
262020
A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma
DC Farhat, MW Bowler, G Communie, D Pontier, L Belmudes, C Mas, ...
Elife 10, e68312, 2021
232021
Polyproteins in structural biology
T Crépin, C Swale, A Monod, F Garzoni, M Chaillet, I Berger
Current Opinion in Structural Biology 32, 139-146, 2015
232015
Binding of RNA by the nucleoproteins of influenza viruses A and B
A Labaronne, C Swale, A Monod, G Schoehn, T Crépin, RWH Ruigrok
Viruses 8 (9), 247, 2016
212016
In vitro production of cat-restricted Toxoplasma pre-sexual stages
AV Antunes, M Shahinas, C Swale, DC Farhat, C Ramakrishnan, C Bruley, ...
Nature, 1-11, 2023
17*2023
First cases of Angiostrongylus cantonensis infection reported in Martinique, 2002–2017
C Dard, E Tessier, D Nguyen, L Epelboin, D Harrois, C Swale, A Cabié, ...
Parasite 27, 2020
132020
CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells
S Krishnamurthy, P Maru, Y Wang, MA Bitew, D Mukhopadhyay, ...
Mbio 14 (2), e00060-23, 2023
112023
X-ray structure of the human karyopherin RanBP5, an essential factor for influenza polymerase nuclear trafficking
C Swale, B Da Costa, L Sedano, F Garzoni, AA McCarthy, I Berger, ...
Journal of molecular biology 432 (10), 3353-3359, 2020
112020
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase
C Swale, V Bellini, MW Bowler, N Flore, MP Brenier-Pinchart, D Cannella, ...
Science Translational Medicine 14 (656), eabn3231, 2022
9*2022
A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection
C Dard, C Swale, MP Brenier-Pinchart, DC Farhat, V Bellini, MG Robert, ...
BMC biology 19, 1-26, 2021
92021
Genome-wide CRISPR screen identifies genes synthetically lethal with GRA17, a nutrient channel encoding gene in Toxoplasma
TC Paredes-Santos, MA Bitew, C Swale, F Rodriguez, S Krishnamurthy, ...
PLoS pathogens 19 (7), e1011543, 2023
72023
Two Toxoplasma gondii putative pore-forming proteins, GRA47 and GRA72, influence small molecule permeability of the parasitophorous vacuole
MA Bitew, PS Gaete, C Swale, P Maru, JE Contreras, JPJ Saeij
Mbio, e03081-23, 2024
2024
3′‐end mRNA processing within apicomplexan parasites, a patchwork of classic, and unexpected players
C Swale, MA Hakimi
Wiley Interdisciplinary Reviews: RNA 14 (5), e1783, 2023
2023
Oxidation-sensitive cysteines drive IL-38 amyloid formation
A Diaz-Barreiro, G Cereghetti, J Tonacini, D Talabot-Ayer, ...
bioRxiv, 2023.03. 26.534252, 2023
2023
New serological marker for the latent form of toxoplasmosis
D Céline, MA Hakimi, H Pelloux, M Brenier-pinchart, C Swale
US Patent App. 17/776,045, 2022
2022
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