| Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability BEL Lauffer, R Mintzer, R Fong, S Mukund, C Tam, I Zilberleyb, B Flicke, ... Journal of Biological Chemistry 288 (37), 26926-26943, 2013 | 412 | 2013 |
| Activation of Notch signaling pathway precedes heart regeneration in zebrafish A Raya, CM Koth, D Büscher, Y Kawakami, T Itoh, RM Raya, G Sternik, ... Proceedings of the National Academy of Sciences 100 (suppl_1), 11889-11895, 2003 | 388 | 2003 |
| Structural basis of Nav1. 7 inhibition by an isoform-selective small-molecule antagonist S Ahuja, S Mukund, L Deng, K Khakh, E Chang, H Ho, S Shriver, C Young, ... Science 350 (6267), aac5464, 2015 | 309 | 2015 |
| Crystal structure of the CorA Mg2+ transporter VV Lunin, E Dobrovetsky, G Khutoreskaya, R Zhang, A Joachimiak, ... Nature 440 (7085), 833-837, 2006 | 309 | 2006 |
| MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb Y Kawakami, J Rodríguez-León, CM Koth, D Büscher, T Itoh, Á Raya, ... Nature cell biology 5 (6), 513-519, 2003 | 300 | 2003 |
| The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10 JK Ng, Y Kawakami, D Büscher, Á Raya, T Itoh, CM Koth, CR Esteban, ... Oxford University Press for The Company of Biologists Limited 129 (22), 5161 …, 2002 | 244 | 2002 |
| Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism E ter Haar, CM Koth, N Abdul-Manan, L Swenson, JT Coll, JA Lippke, ... Structure 18 (9), 1083-1093, 2010 | 212 | 2010 |
| Notch activity induces Nodal expression and mediates the establishment of left–right asymmetry in vertebrate embryos A Raya, Y Kawakami, C Rodrıguez-Esteban, D Büscher, CM Koth, T Itoh, ... Genes & development 17 (10), 1213-1218, 2003 | 209 | 2003 |
| Structural basis of Nav1. 7 inhibition by a gating-modifier spider toxin H Xu, T Li, A Rohou, CP Arthur, F Tzakoniati, E Wong, A Estevez, C Kugel, ... Cell 176 (4), 702-715. e14, 2019 | 197 | 2019 |
| Structural and functional diversity calls for a new classification of ABC transporters C Thomas, SG Aller, K Beis, EP Carpenter, G Chang, L Chen, E Dassa, ... FEBS letters 594 (23), 3767-3775, 2020 | 196 | 2020 |
| Mechanism of intramembrane proteolysis investigated with purified rhomboid proteases MK Lemberg, J Menendez, A Misik, M Garcia, CM Koth, M Freeman The EMBO journal 24 (3), 464-472, 2005 | 188 | 2005 |
| Structural basis for dual-mode inhibition of the ABC transporter MsbA H Ho, A Miu, MK Alexander, NK Garcia, A Oh, I Zilberleyb, M Reichelt, ... Nature 557 (7704), 196-201, 2018 | 147 | 2018 |
| Molecular basis for negative regulation of the glucagon receptor CM Koth, JM Murray, S Mukund, A Madjidi, A Minn, HJ Clarke, T Wong, ... Proceedings of the National Academy of Sciences 109 (36), 14393-14398, 2012 | 142 | 2012 |
| Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab L Rougé, N Chiang, M Steffek, C Kugel, TI Croll, C Tam, A Estevez, ... Science 367 (6483), 1224-1230, 2020 | 119 | 2020 |
| Potassium channels Kv1. 3 and KCa3. 1 cooperatively and compensatorily regulate antigen-specific memory T cell functions EY Chiang, T Li, S Jeet, I Peng, J Zhang, WP Lee, J DeVoss, P Caplazi, ... Nature communications 8 (1), 14644, 2017 | 82 | 2017 |
| High-throughput production of prokaryotic membrane proteins E Dobrovetsky, ML Lu, R Andorn-Broza, G Khutoreskaya, JE Bray, ... Journal of Structural and Functional Genomics 6, 33-50, 2005 | 65 | 2005 |
| A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells AH Nile, F de Sousa e Melo, S Mukund, R Piskol, S Hansen, L Zhou, ... Nature chemical biology 14 (6), 582-590, 2018 | 64 | 2018 |
| A novel inhibitor of the LolCDE ABC transporter essential for lipoprotein trafficking in Gram-negative bacteria NN Nickerson, CC Jao, Y Xu, J Quinn, E Skippington, MK Alexander, ... Antimicrobial agents and chemotherapy 62 (4), 10.1128/aac. 02151-17, 2018 | 63 | 2018 |
| Disrupting gram-negative bacterial outer membrane biosynthesis through inhibition of the lipopolysaccharide transporter MsbA MK Alexander, A Miu, A Oh, M Reichelt, H Ho, C Chalouni, S Labadie, ... Antimicrobial Agents and Chemotherapy 62 (11), 10.1128/aac. 01142-18, 2018 | 61 | 2018 |
| Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor CM Koth, N Abdul-Manan, CA Lepre, PJ Connolly, S Yoo, AK Mohanty, ... Biochemistry 49 (9), 1862-1872, 2010 | 50 | 2010 |
