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Lisa A Stott
Lisa A Stott
Heptares Therapeutics
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Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors
DA Sykes, H Moore, L Stott, N Holliday, JA Javitch, JR Lane, SJ Charlton
Nature communications 8 (1), 763, 2017
1922017
Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data
LA Stott, DA Hall, ND Holliday
Biochemical pharmacology 101, 1-12, 2016
452016
Potent and selective N-(4-sulfamoylphenyl) thiourea-based GPR55 agonists
S Yrjölä, T Parkkari, D Navia-Paldanius, T Laitinen, AA Kaczor, T Kokkola, ...
European journal of medicinal chemistry 107, 119-132, 2016
252016
Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors. Nat Commun. 2017; 8 (1): 763
DA Sykes, H Moore, L Stott, N Holliday, JA Javitch, JR Lane, SJ Charlton
Epub 2017/10/04. https://doi. org/10.1038/s41467-017-00716-z PMID: 28970469, 0
5
The identification of GPR52 agonist HTL0041178, a potential therapy for schizophrenia and related psychiatric disorders
S Poulter, N Austin, R Armstrong, M Barnes, SJ Bucknell, A Higueruelo, ...
ACS Medicinal Chemistry Letters 14 (4), 499-505, 2023
42023
Characterisation of inverse agonism of the orphan-G protein-coupled receptor GPR52 by cannabinoid ligands Cannabidiol and O-1918
LA Stott, CA Brighton, J Brown, R Mould, KA Bennett, R Newman, ...
Heliyon 7 (6), 2021
42021
Effect of HTL0045725, a selective agonist of the orphan receptor GPR52, on kinase and transcription factor phosphorylation in striatal neurons
E Sergeev, L Stott, SJ Bradley, KA Bennett, AJH Brown, SP Watson, ...
Neuroscience Applied 1, 100412, 2022
22022
The neutrophil dynamic mass redistribution assay as a medium throughput primary cell screening assay
LA Stott, AD la Rochelle, S Brown, G Osborne, CJ Hutchings, S Poulter, ...
Journal of Pharmacology and Experimental Therapeutics 389 (1), 19-31, 2024
12024
Validation of a label-free assay to determine chemokine responses in primary human neutrophils
L Stott, G Osborne, K Bennett, S Poulter, C Hutchings, M Barnes
BRITISH JOURNAL OF PHARMACOLOGY 177 (11), 2509-2511, 2020
2020
Comparison of radioligand and TR-FRET binding techniques at the histamine H-4 receptor
D Tippett, LA Stott, G Osborne, M Barnes
BRITISH JOURNAL OF PHARMACOLOGY 176 (16), 2988-2989, 2019
2019
Determination of agonist intrinsic efficacies at the dopamine D2 receptor
LA Stott
University of Nottingham, 2017
2017
Comparison of Radioligand and TR-FRET Binding Techniques at the Histamine H
DN Tippett, LA Stott, G Osborne, M Barnes
membranes 4, 4, 0
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