Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. D Balomenos, R Rumold, AN Theofilopoulos The Journal of clinical investigation 101 (2), 364-371, 1998 | 457 | 1998 |
Lupus susceptibility loci in New Zealand mice. DH Kono, RW Burlingame, DG Owens, A Kuramochi, RS Balderas, ... Proceedings of the National Academy of Sciences 91 (21), 10168-10172, 1994 | 414 | 1994 |
PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus DF Barber, A Bartolomé, C Hernandez, JM Flores, C Redondo, ... Nature medicine 11 (9), 933-935, 2005 | 409 | 2005 |
The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development D Balomenos, J Martín-Caballero, MI García, I Prieto, JM Flores, ... Nature medicine 6 (2), 171-176, 2000 | 249 | 2000 |
Increased phosphoinositide 3‐kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo L R.‐Borlado, C Redondo, B Alvarez, C Jimenez, LM Criado, J Flores, ... The FASEB Journal 14 (7), 895-903, 2000 | 216 | 2000 |
Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity M Murga, O Fernández-Capetillo, SJ Field, B Moreno, R Luis, Y Fujiwara, ... Immunity 15 (6), 959-970, 2001 | 212 | 2001 |
Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells R Rodriguez, R Rubio, M Masip, P Catalina, A Nieto, T de la Cueva, ... Neoplasia 11 (4), 397-IN9, 2009 | 129 | 2009 |
Leukocyte attraction through the CCR5 receptor controls progress from insulitis to diabetes in non‐obese diabetic mice C Carvalho‐Pinto, MI García, L Gómez, A Ballesteros, A Zaballos, ... European journal of immunology 34 (2), 548-557, 2004 | 128 | 2004 |
Autocrine production of IFN-γ by macrophages controls their recruitment to kidney and the development of glomerulonephritis in MRL/lpr mice CE Carvalho-Pinto, MI García, M Mellado, JM Rodríguez-Frade, ... The Journal of Immunology 169 (2), 1058-1067, 2002 | 104 | 2002 |
Class IB-phosphatidylinositol 3-kinase (PI3K) deficiency ameliorates IA-PI3K-induced systemic lupus but not T cell invasion DF Barber, A Bartolomé, C Hernandez, JM Flores, C Fernandez-Arias, ... The Journal of Immunology 176 (1), 589-593, 2006 | 100 | 2006 |
p21 mediates macrophage reprogramming through regulation of p50-p50 NF-κB and IFN-β G Rackov, E Hernández-Jiménez, R Shokri, L Carmona-Rodríguez, ... The Journal of Clinical Investigation 126 (8), 3089-3103, 2016 | 96 | 2016 |
Incomplete T cell receptor V beta allelic exclusion and dual V beta-expressing cells. D Balomenos, RS Balderas, KP Mulvany, J Kaye, DH Kono, ... Journal of immunology (Baltimore, Md.: 1950) 155 (7), 3308-3312, 1995 | 90 | 1995 |
Functional inactivation of CXC chemokine receptor 4–mediated responses through SOCS3 up-regulation SF Soriano, P Hernanz-Falcón, JM Rodríguez-Frade, AM De Ana, ... The Journal of experimental medicine 196 (3), 311-321, 2002 | 87 | 2002 |
Regulation of macrophage activation and septic shock susceptibility via p21(WAF1/CIP1) M Trakala, CF Arias, MI García, MC Moreno‐Ortiz, K Tsilingiri, ... European journal of immunology 39 (3), 810-819, 2009 | 79 | 2009 |
Cell-cycle regulation in immunity, tolerance and autoimmunity D Balomenos, C Martı́nez-A Immunology today 21 (11), 551-555, 2000 | 76 | 2000 |
p21CIP1/WAF1 controls proliferation of activated/memory T cells and affects homeostasis and memory T cell responses CF Arias, A Ballesteros-Tato, MI García, J Martín-Caballero, JM Flores, ... The Journal of Immunology 178 (4), 2296-2306, 2007 | 75 | 2007 |
The proliferative in vivo activities of lpr double-negative T cells and the primary role of p59fyn in their activation and expansion. D Balomenos, R Rumold, AN Theofilopoulos Journal of immunology (Baltimore, Md.: 1950) 159 (5), 2265-2273, 1997 | 60 | 1997 |
Development of lupus in BXSB mice is independent of IL-4 DH Kono, D Balomenos, MS Park, AN Theofilopoulos The Journal of Immunology 164 (1), 38-42, 2000 | 50 | 2000 |
The role of IFN-β during the course of sepsis progression and its therapeutic potential G Rackov, R Shokri, MÁ De Mon, C Martínez-A, D Balomenos Frontiers in immunology 8, 493, 2017 | 45 | 2017 |
Cyclin‐dependent kinase inhibitor p21, via its C‐terminal domain, is essential for resolution of murine inflammatory arthritis M Mavers, CM Cuda, AV Misharin, AK Gierut, H Agrawal, E Weber, ... Arthritis & Rheumatism 64 (1), 141-152, 2012 | 44 | 2012 |