Juan José Galano Frutos
Juan José Galano Frutos
Ph. D. in Biochemistry and Molecular Biology, University of Zaragoza
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Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa
O Secka, DE Berg, M Antonio, T Corrah, M Tapgun, R Walton, V Thomas, ...
Antimicrobial agents and chemotherapy 57 (3), 1231-1237, 2013
432013
Improved Flavodoxin Inhibitors with Potential Therapeutic Effects against Helicobacter pylori Infection
JJ Galano, M Alías, R Pérez, A Velázquez-Campoy, PS Hoffman, ...
Journal of Medicinal Chemistry 56 (15), 6248-6258, 2013
232013
Design, Synthesis, and Efficacy Testing of Nitroethylene- and 7-Nitrobenzoxadiazol-Based Flavodoxin Inhibitors against Helicobacter pylori Drug-Resistant Clinical Strains …
S Salillas, M Alías, V Michel, A Mahía, A Lucía, L Rodrigues, J Bueno, ...
Journal of medicinal chemistry 62 (13), 6102-6115, 2019
62019
The mechanism of water/ion exchange at a protein surface: a weakly bound chloride in Helicobacter pylori apoflavodoxin
JJ Galano-Frutos, MC Morón, J Sancho
Physical Chemistry Chemical Physics 17 (43), 28635-28646, 2015
32015
Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position
JA Gálvez, R Clavería-Gimeno, JJ Galano-Frutos, J Sancho, ...
European journal of medicinal chemistry 171, 401-419, 2019
22019
A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ 1–42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus …
A Mahía, M Conde-Giménez, S Salillas, I Pallarés, JJ Galano-Frutos, ...
Analytical and bioanalytical chemistry 411 (1), 251-265, 2019
22019
QSAR Models for Prediction of Binding and Inhibitory Properties of [(E)-2- R-vinyl]benzene Derivatives with Therapeutic Effects against Helicobacter pylori.
JJ Galano, J Sancho
Medicinal Chemistry 4 (1), 306-312, 2013
22013
Direct examination of the relevance for folding, binding and electron transfer of a conserved protein folding intermediate
E Lamazares, S Vega, P Ferreira, M Medina, JJ Galano-Frutos, ...
Physical Chemistry Chemical Physics 19 (29), 19021-19031, 2017
12017
New variant (Val597Ile) in transmembrane region of the TSH receptor with human chorionic gonadotropin hypersensitivity in familial gestational hyperthyroidism
P Caron, S Broussaud, JJ Galano‐Frutos, J Sancho, F Savagner
Clinical Endocrinology, 2020
2020
Protein haploinsufficiency drivers identify MYBPC3 mutations that cause hypertrophic cardiomyopathy
C Suay-Corredera, MR Pricolo, E Herrero-Galan, D Velazquez-Carreras, ...
MedRxiv, 2020
2020
Molecular dynamics simulations for genetic interpretation in protein coding regions: where we are, where to go and when
JJ Galano-Frutos, H García-Cebollada, J Sancho
Briefings in bioinformatics, 2019
2019
Accurate Calculation of Barnase and SNase Folding Energetics Using Short Molecular Dynamics Simulations and an Atomistic Model of the Unfolded Ensemble: Evaluation of Force …
JJ Galano-Frutos, J Sancho
Journal of Chemical Information and Modeling 59 (10), 4350-4360, 2019
2019
Efficacy of flavodoxin inhibitors against Helicobacter pylori drug-resistant clinical strains and in Hp-infected mice
J Sancho, S Salillas, M Alias, V Michel, A Mahia, A Lucia, L Rodrigues, ...
HELICOBACTER 24, 2019
2019
A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ1–42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus …
A Mahía Moros, M Conde-Giménez, S Salillas, I Pallarés, ...
Springer Nature, 2019
2019
Development of novel stabilizing compounds of human phenylalanine hydroxylase for PKU patients
M Conde-Giménez, S Salillas, JJ Galano-Frutos, M Galiana-Cameo, ...
2018
Fighting superbugs: new promising compounds against Helicobacter pylori
S Salillas, M Alías, V Michel, A Mahía Moros, A Lucía Quintana, ...
2018
Studying the mechanism of action of novel stabilizing compounds of phenylalanine hydroxylase
M Conde-Giménez, S Salillas, JJ Galano-Frutos, M Galiana-Cameo, ...
2017
Helicobacter pylori: eventos biomoleculares asociados a la aparición de resistencia y al mecanismo de intercambio anión/agua en la superficie de flavodoxina. Diseño y …
JJG Frutos
Universidad de Zaragoza, 2015
2015
OPTIMIZATION OF PHENYILALANANINE HYDROXILASE STABILIZERS BY A TESTED ‘ALCHEMICHAL’FREE-ENERGY APPROACH
JJ Galano-Frutos, M Conde-Giménez, M Galiana, BL Victor, RM Brito, ...
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