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Sandeep Yadav
Sandeep Yadav
Sr. Director, Formulation & Fill/Finish
Dirección de correo verificada de sangamo.com
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Weak interactions govern the viscosity of concentrated antibody solutions: high-throughput analysis using the diffusion interaction parameter
BD Connolly, C Petry, S Yadav, B Demeule, N Ciaccio, JMR Moore, ...
Biophysical journal 103 (1), 69-78, 2012
3302012
The influence of charge distribution on self-association and viscosity behavior of monoclonal antibody solutions
S Yadav, TM Laue, DS Kalonia, SN Singh, SJ Shire
Molecular pharmaceutics 9 (4), 791-802, 2012
2832012
Specific interactions in high concentration antibody solutions resulting in high viscosity
S Yadav, J Liu, SJ Shire, DS Kalonia
Journal of pharmaceutical sciences 99 (3), 1152-1168, 2010
2772010
Factors affecting the viscosity in high concentration solutions of different monoclonal antibodies
S Yadav, SJ Shire, DS Kalonia
Journal of pharmaceutical sciences 99 (12), 4812-4829, 2010
2372010
Viscosity behavior of high-concentration monoclonal antibody solutions: correlation with interaction parameter and electroviscous effects
S Yadav, SJ Shire, DS Kalonia
Journal of pharmaceutical sciences 101 (3), 998-1011, 2012
1742012
Establishing a link between amino acid sequences and self-associating and viscoelastic behavior of two closely related monoclonal antibodies
S Yadav, A Sreedhara, S Kanai, J Liu, S Lien, H Lowman, DS Kalonia, ...
Pharmaceutical research 28, 1750-1764, 2011
1462011
Viscosity analysis of high concentration bovine serum albumin aqueous solutions
S Yadav, SJ Shire, DS Kalonia
Pharmaceutical research 28, 1973-1983, 2011
1452011
Monoclonal antibody self-association, cluster formation, and rheology at high concentrations
WG Lilyestrom, S Yadav, SJ Shire, TM Scherer
The Journal of Physical Chemistry B 117 (21), 6373-6384, 2013
1392013
Polysorbate 20 degradation in biopharmaceutical formulations: quantification of free fatty acids, characterization of particulates, and insights into the degradation mechanism
A Tomlinson, B Demeule, B Lin, S Yadav
Molecular pharmaceutics 12 (11), 3805-3815, 2015
1362015
The role of amino acid sequence in the self-association of therapeutic monoclonal antibodies: insights from coarse-grained modeling
A Chaudhri, IE Zarraga, S Yadav, TW Patapoff, SJ Shire, GA Voth
The journal of physical chemistry B 117 (5), 1269-1279, 2013
1182013
Comparison of binding characteristics and in vitro activities of three inhibitors of vascular endothelial growth factor A
J Yang, X Wang, G Fuh, L Yu, E Wakshull, M Khosraviani, ES Day, ...
Molecular pharmaceutics 11 (10), 3421-3430, 2014
982014
Understanding particle formation: solubility of free fatty acids as polysorbate 20 degradation byproducts in therapeutic monoclonal antibody formulations
N Doshi, B Demeule, S Yadav
Molecular pharmaceutics 12 (11), 3792-3804, 2015
942015
Considerations for the use of polysorbates in biopharmaceuticals
MT Jones, HC Mahler, S Yadav, D Bindra, V Corvari, RM Fesinmeyer, ...
Pharmaceutical Research 35, 1-8, 2018
932018
Use of dynamic light scattering to determine second virial coefficient in a semidilute concentration regime
S Yadav, TM Scherer, SJ Shire, DS Kalonia
Analytical biochemistry 411 (2), 292-296, 2011
872011
Solubility challenges in high concentration monoclonal antibody formulations: relationship with amino acid sequence and intermolecular interactions
M Pindrus, SJ Shire, RF Kelley, B Demeule, R Wong, Y Xu, S Yadav
Molecular pharmaceutics 12 (11), 3896-3907, 2015
712015
Compatibility and stability of pertuzumab and trastuzumab admixtures in iv infusion bags for coadministration
ZWK Glover, L Gennaro, S Yadav, B Demeule, PY Wong, A Sreedhara
Journal of pharmaceutical sciences 102 (3), 794-812, 2013
662013
Dipole-dipole interaction in antibody solutions: correlation with viscosity behavior at high concentration
SN Singh, S Yadav, SJ Shire, DS Kalonia
Pharmaceutical research 31, 2549-2558, 2014
642014
Comparative study of analytical techniques for determining protein charge
DI Filoti, SJ Shire, S Yadav, TM Laue
Journal of pharmaceutical sciences 104 (7), 2123-2131, 2015
592015
Degradation Mechanisms of Polysorbate 20 Differentiated by 18O-labeling and Mass Spectrometry
L Zhang, S Yadav, B Demeule, YJ Wang, O Mozziconacci, C Schӧneich
Pharmaceutical research 34, 84-100, 2017
522017
Analytical ultracentrifugation and its role in development and research of therapeutical proteins
J Liu, S Yadav, J Andya, B Demeule, SJ Shire
Methods in enzymology 562, 441-476, 2015
292015
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