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Nicole Déglon
Nicole Déglon
Lausanne University Hospital (CHUV)
Dirección de correo verificada de chuv.ch
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Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
JH Kordower, ME Emborg, J Bloch, SY Ma, Y Chu, L Leventhal, J McBride, ...
Science 290 (5492), 767-773, 2000
14662000
α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
C Lo Bianco, JL Ridet, BL Schneider, N Deglon, P Aebischer
Proceedings of the National Academy of Sciences 99 (16), 10813-10818, 2002
6092002
Intrathecal delivery of CNTF using encapsulated genetically modifiedxenogeneic cells in amyotrophic lateral sclerosis patients
P Aebischer, M Schluep, N Déglon, JM Joseph, L Hirt, B Heyd, ...
Nature medicine 2 (6), 696-699, 1996
5431996
Lentiviral-mediated RNA interference
T Abbas-Terki, W Blanco-Bose, N Déglon, W Pralong, P Aebischer
Human gene therapy 13 (18), 2197-2201, 2002
4432002
Isolation of multipotent neural precursors residing in the cortex of the adult human brain
Y Arsenijevic, JG Villemure, JF Brunet, JJ Bloch, N Déglon, C Kostic, ...
Experimental neurology 170 (1), 48-62, 2001
4132001
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
N Deglon, JL Tseng, JC Bensadoun, AD Zurn, Y Arsenijevic, ...
Human gene therapy 11 (1), 179-190, 2000
3402000
Mitochondria in Huntington's disease
M Damiano, L Galvan, N Déglon, E Brouillet
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (1), 52-61, 2010
3062010
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease …
M Faideau, J Kim, K Cormier, R Gilmore, M Welch, G Auregan, N Dufour, ...
Human molecular genetics 19 (15), 3053-3067, 2010
2962010
Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
U Pannasch, D Freche, G Dallérac, G Ghézali, C Escartin, P Ezan, ...
Nature neuroscience 17 (4), 549-558, 2014
2852014
Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin
A Benchoua, Y Trioulier, D Zala, MC Gaillard, N Lefort, N Dufour, ...
Molecular biology of the cell 17 (4), 1652-1663, 2006
2712006
Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study
J Bloch, AC Bachoud-Levi, N Deglon, JP Lefaucheur, L Winkel, S Palfi, ...
Human gene therapy 15 (10), 968-975, 2004
2552004
Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF
JC Bensadoun, N Déglon, JL Tseng, JL Ridet, AD Zurn, P Aebischer
Experimental neurology 164 (1), 15-24, 2000
2492000
Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration
S Palfi, L Leventhal, Y Chu, SY Ma, M Emborg, R Bakay, N Déglon, ...
Journal of Neuroscience 22 (12), 4942-4954, 2002
2442002
Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression …
LP De Almeida, CA Ross, D Zala, P Aebischer, N Déglon
Journal of Neuroscience 22 (9), 3473-3483, 2002
2422002
Sustained effects of nonallele‐specific Huntingtin silencing
V Drouet, V Perrin, R Hassig, N Dufour, G Auregan, S Alves, G Bonvento, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
2412009
Lentiviral gene transfer to the nonhuman primate brain
JH Kordower, J Bloch, SY Ma, Y Chu, S Palfi, BZ Roitberg, M Emborg, ...
Experimental neurology 160 (1), 1-16, 1999
2311999
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
S Dujardin, K Lécolle, R Caillierez, S Bégard, N Zommer, C Lachaud, ...
Acta neuropathologica communications 2 (1), 1-14, 2014
2282014
Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy
A Huber, V Padrun, N Déglon, P Aebischer, H Möhler, D Boison
Proceedings of the National Academy of Sciences 98 (13), 7611-7616, 2001
2252001
BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities
G Quesseveur, DJ David, MC Gaillard, P Pla, MV Wu, HT Nguyen, ...
Translational psychiatry 3 (4), e253-e253, 2013
2112013
Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus
AF Hottinger, M Azzouz, N Deglon, P Aebischer, AD Zurn
Journal of Neuroscience 20 (15), 5587-5593, 2000
2082000
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