| Clinically significant pharmacokinetic interactions between dietary caffeine and medications JA Carrillo, J Benitez Clinical pharmacokinetics 39, 127-153, 2000 | 520 | 2000 |
| Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test. L Bertilsson, JA Carrillo, ML Dahl, A Llerena, C Alm, U Bondesson, ... British journal of clinical pharmacology 38 (5), 471-473, 1994 | 389 | 1994 |
| Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population JAG Agúndez, MC Ledesma, JM Ladero, J Benítez Clinical Pharmacology & Therapeutics 57 (3), 265-269, 1995 | 255 | 1995 |
| Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism M Oscarson, RA McLellan, H Gullstén, JAG Agúndez, J Benı́tez, A Rautio, ... FEBS letters 460 (2), 321-327, 1999 | 242 | 1999 |
| Role of the smoking-induced cytochrome P450 (CYP) 1A2 and polymorphic CYP2D6 in steady-state concentration of olanzapine JA Carrillo, AG Herráiz, SI Ramos, G Gervasini, S Vizcaíno, J Benítez Journal of clinical psychopharmacology 23 (2), 119-127, 2003 | 226 | 2003 |
| Relationship between personality and debrisoquine hydroxylation capacity: suggestion of an endogenous neuroactive substrate or product of the cytochrome P4502D6 A Llerena, G Edman, J Cobaleda, J Benitez, D Schalling, L Bertilsson Acta Psychiatrica Scandinavica 87 (1), 23-28, 1993 | 191 | 1993 |
| Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2‐receptor antagonists C Martínez, C Albet, JAG Agúndez, E Herrero, JA Carrillo, M Márquez, ... Clinical pharmacology & therapeutics 65 (4), 369-376, 1999 | 187 | 1999 |
| Evaluation of caffeine as an in vivo probe for CYP1A2 using measurements in plasma, saliva, and urine JA Carrillo, M Christensen, SI Ramos, C Alm, ML Dahl, J Benítez, ... Therapeutic drug monitoring 22 (4), 409-417, 2000 | 164 | 2000 |
| CYP1A2 activity, gender and smoking, as variables influencing the toxicity of caffeine JA CARRILLO, J BENITEZ British journal of clinical pharmacology 41 (6), 605-608, 1996 | 153 | 1996 |
| Impact of genetic polymorphisms on tacrolimus pharmacokinetics and the clinical outcome of renal transplantation G Gervasini, M Garcia, RM Macias, JJ Cubero, F Caravaca, J Benitez Transplant international 25 (4), 471-480, 2012 | 125 | 2012 |
| Possible implications of doxycycline-rifampin interaction for treatment of brucellosis JD Colmenero, LC Fernandez-Gallardo, JA Agundez, J Sedeno, J Benitez, ... Antimicrobial agents and chemotherapy 38 (12), 2798-2802, 1994 | 120 | 1994 |
| Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients JA Carrillo, AG Herraiz, SI Ramos, J Benitez Journal of clinical psychopharmacology 18 (4), 311-316, 1998 | 119 | 1998 |
| Interethnic differences in drug metabolism: influence of genetic and environmental factors on debrisoquine hydroxylation phenotype A Llerena, J Cobaleda, C Martinez, J Benitez European journal of drug metabolism and pharmacokinetics 21, 129-138, 1996 | 114 | 1996 |
| Caffeine metabolism in a healthy Spanish population: N‐Acetylator phenotype and oxidation pathways JA Carrillo, J Benítez Clinical Pharmacology & Therapeutics 55 (3), 293-304, 1994 | 110 | 1994 |
| Pharmacogenetic testing and therapeutic drug monitoring are complementary tools for optimal individualization of drug therapy G Gervasini, J Benítez, JA Carrillo European journal of clinical pharmacology 66, 755-774, 2010 | 105 | 2010 |
| Association between the oxidative polymorphism and early onset of Parkinson's disease JAG Agúndez, FJ Jiménez‐Jiménez, A Luengo, ML Bernal, JA Molina, ... Clinical Pharmacology & Therapeutics 57 (3), 291-298, 1995 | 101 | 1995 |
| Adenosine triphosphate‐binding cassette B1 (ABCB1)(multidrug resistance 1) G2677T/A gene polymorphism is associated with high risk of lung cancer G Gervasini, JA Carrillo, M Garcia, C San Jose, A Cabanillas, J Benitez Cancer 107 (12), 2850-2857, 2006 | 94 | 2006 |
| Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients JA Carrillo, SI Ramos, AG Herraiz, A Llerena, JAG Agundez, R Berecz, ... Journal of clinical psychopharmacology 19 (6), 494-499, 1999 | 94 | 1999 |
| Acetylator polymorphism in human colorectal carcinoma JM Ladero, JF González, J Benítez, E Vargas, MJ Fernández, W Baki, ... Cancer research 51 (8), 2098-2100, 1991 | 93 | 1991 |
| Lung cancer and mutations at the polymorphic NAT2 gene locus C Martínez, JAG Agúndez, M Olivera, R Martín, JM Ladero, J Benítez Pharmacogenetics and Genomics 5 (4), 207-214, 1995 | 90 | 1995 |
