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Nelson Varela
Nelson Varela
Profesor Asociado, Facultad de Medicina, Universidad de Chile
Dirección de correo verificada de med.uchile.cl
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Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients
LA Videla, R Rodrigo, M Orellana, V Fernandez, G Tapia, L Quiñones, ...
Clinical science 106 (3), 261-268, 2004
5992004
CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
L Quinones, D Lucas, J Godoy, D Cáceres, F Berthou, N Varela, K Lee, ...
Cancer letters 174 (1), 35-44, 2001
1752001
Relationship between in vivo chlorzoxazone hydroxylation, hepatic cytochrome P450 2E1 content and liver injury in obese non-alcoholic fatty liver disease patients
M Orellana, R Rodrigo, N Varela, J Araya, J Poniachik, A Csendes, ...
Hepatology research 34 (1), 57-63, 2006
1012006
Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
L Quinones, F Berthou, N Varela, B Simon, L Gil, D Lucas
Cancer letters 141 (1-2), 167-171, 1999
891999
Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the Chilean population: comparison with Caucasian and Asian …
Á Roco, L Quiñones, JAG Agúndez, E García-Martín, V Squicciarini, ...
Frontiers in genetics 3, 229, 2012
852012
Impaired cell cycle regulation of the osteoblast‐related heterodimeric transcription factor Runx2‐Cbfβ in osteosarcoma cells
IA San Martin, N Varela, M Gaete, K Villegas, M Osorio, JC Tapia, ...
Journal of cellular physiology 221 (3), 560-571, 2009
722009
Joint effect among p53, CYP1A1, GSTM1 polymorphism combinations and smoking on prostate cancer risk: an exploratory genotype‐environment interaction study
LA Quiñones, CE Irarrázabal, CR Rojas, CE Orellana, C Acevedo, ...
Asian Journal of andrology 8 (3), 349-355, 2006
692006
Relationship among metabolizing genes, smoking and alcohol used as modifier factors on prostate cancer risk: exploring some gene–gene and gene–environment interactions
DD Cáceres L, J Iturrieta G, C Acevedo C, C Huidobro A, N Varela F, ...
European journal of epidemiology 20, 79-88, 2005
542005
Study of cytochrome P450 2E1 and its allele variants in liver injury of nondiabetic, nonalcoholic steatohepatitis obese women
NM Varela, LA Quiñones, M Orellana, J Poniachik, A Csendes, G Smok, ...
Biological research 41 (1), 81-92, 2008
522008
The cancer‐related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to …
F Villanueva, H Araya, P Briceño, N Varela, A Stevenson, S Jerez, ...
Journal of cellular physiology 234 (8), 13659-13679, 2019
412019
Farmacogenómica como herramienta fundamental para la medicina personalizada: aplicaciones en la práctica clínica
L Quiñones, Á Roco, JP Cayún, P Escalante, C Miranda, N Varela, ...
Revista médica de Chile 145 (4), 483-500, 2017
342017
Characterization of the CYP2D6 drug metabolizing phenotypes of the Chilean mestizo population through polymorphism analyses
N Varela, LA Quinones, J Stojanova, J Garay, D Cáceres, S Cespedes, ...
Pharmacological Research 101, 124-129, 2015
342015
As3MT and GST polymorphisms influencing arsenic metabolism in human exposure to drinking groundwater
F González-Martínez, D Sánchez-Rodas, NM Varela, CA Sandoval, ...
International Journal of Molecular Sciences 21 (14), 4832, 2020
282020
Upregulation of rat liver PPARα‐FGF21 signaling by a docosahexaenoic acid and thyroid hormone combined protocol
LA Videla, V Fernández, R Vargas, P Cornejo, G Tapia, N Varela, ...
Biofactors 42 (6), 638-646, 2016
272016
Farmacogenética, tabaco, alcohol y su efecto sobre el riesgo de desarrollar cáncer
Á Roco, B Cerda, JP Cayún, A Lavanderos, JC Rubilar, R Cerro, ...
Revista chilena de pediatría 89 (4), 432-440, 2018
262018
Clinical applications of pharmacogenomics.
L Quiñones, Á Roco, JP Cayún, P Escalante, C Miranda, N Varela, ...
Revista médica de Chile 145 (4), 483-500, 2017
262017
Mitotic inheritance of mRNA facilitates translational activation of the osteogenic‐Lineage commitment factor runx2 in progeny of osteoblastic cells
N Varela, A Aranguiz, C Lizama, H Sepulveda, M Antonelli, R Thaler, ...
Journal of cellular physiology 231 (5), 1001-1014, 2016
242016
Cancer pharmacogenetics: study of genetically determined variations on cancer susceptibility due to xenobiotic exposure
K García1c, L Godoy1c, A Castro1c, J Soto1d, I Saavedra2e, D Cáceres3f
Rev Med Chile 134, 499-515, 2006
232006
Modulation of rat liver cytochrome P450 activity by prolonged red wine consumption
M Orellana, N Varela, V Guajardo, J Araya, R Rodrigo
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2002
232002
Allelic variants of cytochrome P4501A1 (CYP1A1), glutathione S transferase M1 (GSTM1) polymorphisms and their association with smoking and alcohol consumption as gastric cancer …
K Lee, D Cáceres, N Varela, DA Csendes, RH Rios, SL Quinones
Revista Médica de Chile 134 (9), 1107-1115, 2006
222006
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