Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis V Molodtsov, NT Scharf, MA Stefan, GA Garcia, KS Murakami Molecular microbiology 103 (6), 1034-1045, 2017 | 100 | 2017 |
Source of the fitness defect in rifamycin-resistant Mycobacterium tuberculosis RNA polymerase and the mechanism of compensation by mutations in the β′ subunit MA Stefan, FS Ugur, GA Garcia Antimicrobial agents and chemotherapy 62 (6), 10.1128/aac. 00164-18, 2018 | 34 | 2018 |
Discovery of small-molecule inhibitors of SARS-CoV-2 proteins using a computational and experimental pipeline EY Lau, OA Negrete, WFD Bennett, BJ Bennion, M Borucki, F Bourguet, ... Frontiers in Molecular Biosciences 8, 678701, 2021 | 22 | 2021 |
Development of potent and effective synthetic SARS-CoV-2 neutralizing nanobodies MA Stefan, YK Light, JL Schwedler, PR McIlroy, CM Courtney, EA Saada, ... MAbs 13 (1), 1958663, 2021 | 15 | 2021 |
High-throughput virtual screening of small molecule inhibitors for SARS-CoV-2 protein targets with deep fusion models GA Stevenson, D Jones, H Kim, WFD Bennett, BJ Bennion, M Borucki, ... Proceedings of the International Conference for High Performance Computing …, 2021 | 12 | 2021 |
High-throughput screening to discover inhibitors of the CarD·RNA polymerase protein–protein interaction in Mycobacterium tuberculosis MA Stefan, GM Velazquez, GA Garcia Scientific reports 10 (1), 21309, 2020 | 9 | 2020 |
Therapeutic efficacy of a potent anti-Venezuelan equine encephalitis virus antibody is contingent on Fc effector function JL Schwedler, MA Stefan, CE Thatcher, PR McIlroy, A Sinha, AM Phillips, ... Mabs 16 (1), 2297451, 2024 | 1 | 2024 |
High-Throughput Virtual Screening of Small Molecule Inhibitors for SARS-CoV-2 Protein Targets with Deep Fusion Models (preprint) GA Stevenson, D Jones, H Kim, WFD Bennett, BJ Bennion, M Borucki, ... | 1 | 2021 |
Therapeutic efficacy of a potent anti-VEEV antibody is contingent on humoral and cell-mediated cytotoxic immunity. J Schwedler, M Stefan, A Sinha, P Mcilroy, C Thatcher, C Kim, ... Sandia National Lab.(SNL-CA), Livermore, CA (United States), 2022 | | 2022 |
Characterization of SNL identified BBB-penetrating moieties (BBB PMs) for delivery of therapeutic cargo to the CNS. C Sumner, J Schwedler, M Stefan, A Sinha, P Mcilroy, C Thatcher, CY Kim, ... Sandia National Lab.(SNL-CA), Livermore, CA (United States), 2022 | | 2022 |
DISCOVERY, DESIGN, AND ENGINEERING OF NANOBODY-BASED THERAPEUTICS FOR SARS-COV-2. B Harmon, LTM Pham, P Mcilroy, A Sinha, J Jaryenneh, Y Light, ... Sandia National Lab.(SNL-CA), Livermore, CA (United States); Sandia National …, 2022 | | 2022 |
Protein Display to Discover and Engineer Viral Neutralizing Antibodies. M Stefan, B Harmon, J Schwedler Sandia National Lab.(SNL-NM), Albuquerque, NM (United States), 2021 | | 2021 |
Development of Potent and Effective SARS-CoV-2 Neutralizing Nanobodies. M Stefan, YK Light, J Schwedler, DR Weilhammer, BN Harmon Sandia National Lab.(SNL-CA), Livermore, CA (United States), 2021 | | 2021 |
Combining Computational Modeling with Library Screening to Adapt SARS-CoV-Neutralizing Antibody 80R to SARS-CoV-2 MS Kent, M Stefan, K Sale, C Hudson, D Martinez, M Juarros, B Harmon, ... Biophysical Journal 120 (3), 21a, 2021 | | 2021 |
Development of Potent and Effective Synthetic SARS-CoV-2 Neutralizing Nanobodies (preprint) M Stefan, Y Light, J Schwedler, P McIlroy, C Courtney, E Saada, ... | | 2021 |
Rapidly Adapting Neutralizing Antibodies to Related Virus Types and Subtypes. MS Kent, M Stefan, BN Harmon, D Gelperin, V Duva, A Wynne, ... Sandia National Lab.(SNL-NM), Albuquerque, NM (United States); Sandia …, 2021 | | 2021 |
Adapting Neutralizing Antibodies to Related Virus Types and Subtypes. MS Kent, M Stefan, BN Harmon Sandia National Lab.(SNL-NM), Albuquerque, NM (United States); Sandia …, 2020 | | 2020 |
Deactivation of SARS-CoV-2 by Boronic Acid-Functionalized Polymer GD Bachand, BN Harmon, BH Jones, PR Miller, JB Ricken, M Stefan Sandia National Lab.(SNL-NM), Albuquerque, NM (United States); Sandia …, 2020 | | 2020 |
Development of Blood Brain Barrier Penetrating Antibody Therapeutics for Encephalitic Alphaviruses. M Stefan, J Schwedler, BN Harmon, D Weilhammer, M Diamond Sandia National Lab.(SNL-CA), Livermore, CA (United States), 2019 | | 2019 |
Characterizing differential expression of transmembrane protein 30A. N Friedberg, J Schwedler, M Stefan, BN Harmon Sandia National Lab.(SNL-CA), Livermore, CA (United States), 2019 | | 2019 |