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Raquel Buj
Raquel Buj
UPMC Hillman Cancer Center and the Department of Pharmacology and Chemical Biology of the University
Dirección de correo verificada de upmc.edu
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DNA methylation profiling of well‐differentiated thyroid cancer uncovers markers of recurrence free survival
V Mancikova, R Buj, E Castelblanco, L Inglada‐Pérez, A Diez, ...
International Journal of cancer 135 (3), 598-610, 2014
852014
Deoxyribonucleotide triphosphate metabolism in cancer and metabolic disease
R Buj, KM Aird
Frontiers in endocrinology 9, 362600, 2018
672018
Molecular profiling for acromegaly treatment: a validation study
M Puig-Domingo, J Gil, M Sampedro-Nuñez, M Jordà, SM Webb, G Serra, ...
Endocrine-Related Cancer 27 (6), 375-389, 2020
512020
Suppression of p16 alleviates the senescence-associated secretory phenotype
R Buj, KE Leon, MA Anguelov, KM Aird
Aging (Albany NY) 13 (3), 3290, 2021
472021
Suppression of p16 induces mTORC1-mediated nucleotide metabolic reprogramming
R Buj, CW Chen, ES Dahl, KE Leon, R Kuskovsky, N Maglakelidze, ...
Cell reports 28 (8), 1971-1980. e8, 2019
442019
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A
KE Leon, R Buj, E Lesko, ES Dahl, CW Chen, NK Tangudu, ...
Journal of Cell Biology 220 (8), e202008101, 2021
432021
Targeting IDH1 as a prosenescent therapy in high-grade serous ovarian cancer
ES Dahl, R Buj, KE Leon, JM Newell, Y Imamura, BG Bitler, NW Snyder, ...
Molecular Cancer Research 17 (8), 1710-1720, 2019
322019
DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1
J Huertas-Martínez, F Court, S Rello-Varona, D Herrero-Martin, ...
Cancer letters 386, 196-207, 2017
302017
Increased global DNA hypomethylation in distant metastatic and dedifferentiated thyroid cancer
EN Klein Hesselink, C Zafon, N Villalmanzo, C Iglesias, BM van Hemel, ...
The Journal of Clinical Endocrinology & Metabolism 103 (2), 397-406, 2018
252018
p16: cycling off the beaten path
R Buj, KM Aird
Molecular & cellular oncology 6 (6), e1677140, 2019
192019
Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry
R Kuskovsky, R Buj, P Xu, S Hofbauer, MT Doan, H Jiang, A Bostwick, ...
Analytical biochemistry 568, 65-72, 2019
172019
Quantification of unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples
R Buj, I Mallona, A Díez-Villanueva, V Barrera, D Mauricio, ...
Oncotarget 7 (9), 10536, 2016
172016
Loss of p16: a bouncer of the immunological surveillance?
KE Leon, NK Tangudu, KM Aird, R Buj
Life 11 (4), 309, 2021
152021
Kallikreins stepwise scoring reveals three subtypes of papillary thyroid cancer with prognostic implications
R Buj, I Mallona, A Diez-Villanueva, C Zafon, JL Mate, M Roca, ...
Thyroid 28 (5), 601-612, 2018
142018
A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector
R Buj, N Iglesias, AM Planas, T Santalucia
BMC molecular biology 14, 1-17, 2013
132013
Molecular determinants of enhanced response to somatostatin receptor ligands after debulking in large GH‐producing adenomas
J Gil, M Marques‐Pamies, M Jordà, C Fajardo‐Montañana, ...
Clinical Endocrinology 94 (5), 811-819, 2021
92021
ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells
CW Chen, R Buj, ES Dahl, KE Leon, KM Aird
Heliyon 6 (9), 2020
82020
ATM inhibition drives metabolic adaptation via induction of macropinocytosis
Z Huang, CW Chen, R Buj, NK Tangudu, RS Fang, KE Leon, ES Dahl, ...
Journal of Cell Biology 222 (1), e202007026, 2022
72022
Deoxyribonucleotide triphosphate metabolism in cancer and metabolic disease. Front Endocrinol (Lausanne). 2018; 9: 177
R Buj, KM Aird
Epub 2018/05/04. doi: 10.3389/fendo. 2018.00177. PubMed PMID: 29720963, 0
4
Overexpression of oncogenic H-Ras in hTERT-immortalized and SV40-transformed human cells targets replicative and specialized DNA polymerases for depletion
W Tsao, R Buj, KM Aird, JM Sidorova, KA Eckert
PloS one 16 (5), e0251188, 2021
32021
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Artículos 1–20