Manuel Irimia
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A compendium of RNA-binding motifs for decoding gene regulation
D Ray, H Kazan, KB Cook, MT Weirauch, HS Najafabadi, X Li, ...
Nature 499 (7457), 172-177, 2013
10572013
The evolutionary landscape of alternative splicing in vertebrate species
NL Barbosa-Morais, M Irimia, Q Pan, HY Xiong, S Gueroussov, LJ Lee, ...
Science 338 (6114), 1587-1593, 2012
8152012
Elephant shark genome provides unique insights into gnathostome evolution
B Venkatesh, AP Lee, V Ravi, AK Maurya, MM Lian, JB Swann, Y Ohta, ...
Nature 505 (7482), 174-179, 2014
5622014
Widespread intron retention in mammals functionally tunes transcriptomes
U Braunschweig, NL Barbosa-Morais, Q Pan, EN Nachman, B Alipanahi, ...
Genome research 24 (11), 1774-1786, 2014
4482014
A highly conserved program of neuronal microexons is misregulated in autistic brains
M Irimia, RJ Weatheritt, JD Ellis, NN Parikshak, ...
Cell 159 (7), 1511-1523, 2014
3742014
Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism
NN Parikshak, V Swarup, TG Belgard, M Irimia, G Ramaswami, ...
Nature 540 (7633), 423-427, 2016
3572016
Tissue-specific alternative splicing remodels protein-protein interaction networks
JD Ellis, M Barrios-Rodiles, R Çolak, M Irimia, TH Kim, JA Calarco, ...
Molecular cell 46 (6), 884-892, 2012
3502012
Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs
BA Curtis, G Tanifuji, F Burki, A Gruber, M Irimia, S Maruyama, MC Arias, ...
Nature 492 (7427), 59-65, 2012
3342012
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming
H Han, M Irimia, PJ Ross, HK Sung, B Alipanahi, L David, A Golipour, ...
Nature 498 (7453), 241-245, 2013
2662013
Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling
M Clarke, AJ Lohan, B Liu, I Lagkouvardos, S Roy, N Zafar, C Bertelli, ...
Genome biology 14 (2), 1-15, 2013
2512013
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary
T Khare, S Pai, K Koncevicius, M Pal, E Kriukiene, Z Liutkeviciute, M Irimia, ...
Nature structural & molecular biology 19 (10), 1037-1043, 2012
2322012
A comparative transcriptomic analysis reveals conserved features of stem cell pluripotency in planarians and mammals
RM Labbé, M Irimia, KW Currie, A Lin, SJ Zhu, DDR Brown, EJ Ross, ...
Stem cells 30 (8), 1734-1745, 2012
1832012
Alternative splicing: decoding an expansive regulatory layer
M Irimia, BJ Blencowe
Current opinion in cell biology 24 (3), 323-332, 2012
1502012
An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms
J Tapial, KCH Ha, T Sterne-Weiler, A Gohr, U Braunschweig, ...
Genome research 27 (10), 1759-1768, 2017
1372017
Origin of spliceosomal introns and alternative splicing
M Irimia, SW Roy
Cold Spring Harbor perspectives in biology 6 (6), a016071, 2014
1272014
Regulated aggregative multicellularity in a close unicellular relative of metazoa
A Sebé-Pedrós, M Irimia, J Del Campo, H Parra-Acero, C Russ, ...
Elife 2, e01287, 2013
1162013
Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints
M Irimia, JJ Tena, MS Alexis, A Fernandez-Miñan, I Maeso, O Bogdanović, ...
Genome research 22 (12), 2356-2367, 2012
1082012
Amphioxus functional genomics and the origins of vertebrate gene regulation
F Marlétaz, PN Firbas, I Maeso, JJ Tena, O Bogdanovic, M Perry, ...
Nature 564 (7734), 64-70, 2018
1072018
A global regulatory mechanism for activating an exon network required for neurogenesis
B Raj, M Irimia, U Braunschweig, T Sterne-Weiler, D O’Hanlon, ZY Lin, ...
Molecular cell 56 (1), 90-103, 2014
1022014
MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation
JP Venables, L Lapasset, G Gadea, P Fort, R Klinck, M Irimia, E Vignal, ...
Nature communications 4 (1), 1-10, 2013
1012013
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Artículos 1–20