| Identification of context-dependent expression quantitative trait loci in whole blood DV Zhernakova, P Deelen, M Vermaat, M Van Iterson, M Van Galen, ... Nature genetics 49 (1), 139-145, 2017 | 434 | 2017 |
| Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ... Nature genetics 53 (12), 1636-1648, 2021 | 280 | 2021 |
| Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases N de Klein, EA Tsai, M Vochteloo, D Baird, Y Huang, CY Chen, ... Nature genetics 55 (3), 377-388, 2023 | 102 | 2023 |
| Deconvolution of bulk blood eQTL effects into immune cell subpopulations R Aguirre-Gamboa, N de Klein, J di Tommaso, A Claringbould, ... BMC bioinformatics 21, 1-23, 2020 | 48 | 2020 |
| TMEM258 is a component of the oligosaccharyltransferase complex controlling ER stress and intestinal inflammation DB Graham, A Lefkovith, P Deelen, N de Klein, M Varma, A Boroughs, ... Cell reports 17 (11), 2955-2965, 2016 | 46 | 2016 |
| Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption I Karabegović, E Portilla-Fernandez, Y Li, J Ma, SCE Maas, D Sun, EA Hu, ... Nature communications 12 (1), 2830, 2021 | 44 | 2021 |
| Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity S Rodius, N de Klein, C Jeanty, H Sánchez-Iranzo, I Crespo, M Ibberson, ... Scientific reports 10 (1), 2896, 2020 | 42 | 2020 |
| Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults P Parmar, E Lowry, G Cugliari, M Suderman, R Wilson, V Karhunen, ... EBioMedicine 38, 206-216, 2018 | 34 | 2018 |
| Meta-analyses identify DNA methylation associated with kidney function and damage P Schlosser, A Tin, PR Matias-Garcia, CHL Thio, R Joehanes, H Liu, ... Nature communications 12 (1), 7174, 2021 | 30 | 2021 |
| Analysis of the dynamic co-expression network of heart regeneration in the zebrafish S Rodius, A Fournier, L Götz, R Liechti, I Crespo, S Merz, PV Nazarov, ... Scientific reports 6 (1), 26822, 2016 | 29 | 2016 |
| A comprehensive analysis of microProteins reveals their potentially widespread mechanism of transcriptional regulation E Magnani, N de Klein, HI Nam, JG Kim, K Pham, E Fiume, MB Mudgett, ... Plant physiology 165 (1), 149-159, 2014 | 27 | 2014 |
| Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells OB Bakker, AD Ramírez-Sánchez, ZA Borek, N de Klein, Y Li, ... Scientific reports 11 (1), 9252, 2021 | 10 | 2021 |
| The genetic architecture of molecular traits A Claringbould, N de Klein, L Franke Current Opinion in Systems Biology 1, 25-31, 2017 | 7 | 2017 |
| microProtein Prediction Program (miP3): A software for predicting microProteins and their target transcription factors N de Klein, E Magnani, M Banf, SY Rhee International journal of genomics 2015, 2015 | 7 | 2015 |
| Feasibility of predicting allele specific expression from DNA sequencing using machine learning Z Zhang, F van Dijk, N de Klein, ME van Gijn, LH Franke, RJ Sinke, ... Scientific reports 11 (1), 10606, 2021 | 5 | 2021 |
| KidneyNetwork: using kidney-derived gene expression data to predict and prioritize novel genes involved in kidney disease F Boulogne, LR Claus, H Wiersma, R Oelen, F Schukking, N de Klein, S Li, ... European Journal of Human Genetics 31 (11), 1300-1308, 2023 | 4 | 2023 |
| Imbalanced expression for predicted high-impact, autosomal-dominant variants in a cohort of 3,818 healthy samples N de Klein, F van Dijk, P Deelen, CG Urzua, A Claringbould, U Võsa, ... bioRxiv, 2020.09. 19.300095, 2020 | 3 | 2020 |
| A gene mapping bottleneck in the translational route from zebrafish to human N Klein, M Ibberson, I Crespo, S Rodius, F Azuaje Frontiers in genetics 5, 126188, 2015 | 3 | 2015 |
| A framework for discovering, designing, and testing microproteins to regulate synthetic transcriptional modules E Fiume, N de Klein, SY Rhee, E Magnani Plant Synthetic Promoters: Methods and Protocols, 175-188, 2016 | 2 | 2016 |
| Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific … W van Rheenen, RAA van der Spek, MK Bakker, JJFA van Vugt, PJ Hop, ... Nature genetics 54 (3), 361-361, 2022 | 1 | 2022 |
Lude FrankeProfessor of Functional Genomics, University Medical Centre GroningenVerified email at cleverfranke.com
