| Downstream bioprocessing: recent advances and future promise SM Cramer, MA Holstein Current Opinion in Chemical Engineering 1 (1), 27-37, 2011 | 160 | 2011 |
| Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR WK Chung, AS Freed, MA Holstein, SA McCallum, SM Cramer Proceedings of the National Academy of Sciences 107 (39), 16811-16816, 2010 | 90 | 2010 |
| Mobile phase modifier effects in multimodal cation exchange chromatography MA Holstein, S Parimal, SA McCallum, SM Cramer Biotechnology and bioengineering 109 (1), 176-186, 2012 | 70 | 2012 |
| Investigation of protein binding affinity in multimodal chromatographic systems using a homologous protein library WK Chung, Y Hou, M Holstein, A Freed, GI Makhatadze, SM Cramer Journal of Chromatography A 1217 (2), 191-198, 2010 | 66 | 2010 |
| Continuous in‐line virus inactivation for next generation bioprocessing C Gillespie, M Holstein, L Mullin, K Cotoni, R Tuccelli, J Caulmare, ... Biotechnology Journal 14 (2), 1700718, 2019 | 61 | 2019 |
| Improving selectivity in multimodal chromatography using controlled pH gradient elution MA Holstein, AAM Nikfetrat, M Gage, AG Hirsh, SM Cramer Journal of Chromatography A 1233, 152-155, 2012 | 54 | 2012 |
| Investigation of protein binding affinity and preferred orientations in ion exchange systems using a homologous protein library WK Chung, Y Hou, A Freed, M Holstein, GI Makhatadze, SM Cramer Biotechnology and bioengineering 102 (3), 869-881, 2009 | 54 | 2009 |
| Probing multimodal ligand binding regions on ubiquitin using nuclear magnetic resonance, chromatography, and molecular dynamics simulations MA Holstein, WK Chung, S Parimal, AS Freed, B Barquera, SA McCallum, ... Journal of Chromatography A 1229, 113-120, 2012 | 41 | 2012 |
| Real‐time monitoring of quality attributes by in‐line Fourier transform infrared spectroscopic sensors at ultrafiltration and diafiltration of bioprocess DP Wasalathanthri, H Feroz, N Puri, J Hung, G Lane, M Holstein, ... Biotechnology and Bioengineering 117 (12), 3766-3774, 2020 | 29 | 2020 |
| Strategies for high‐concentration drug substance manufacturing to facilitate subcutaneous administration: A review M Holstein, J Hung, H Feroz, S Ranjan, C Du, S Ghose, ZJ Li Biotechnology and Bioengineering 117 (11), 3591-3606, 2020 | 25 | 2020 |
| Effects of urea on selectivity and protein–ligand interactions in multimodal cation exchange chromatography MA Holstein, S Parimal, SA McCallum, SM Cramer Langmuir 29 (1), 158-167, 2013 | 25 | 2013 |
| Using continuous chromatography methodology to achieve high-productivity and high-purity enrichment of charge variants for analytical characterization E Bigelow, Y Song, J Chen, M Holstein, Y Huang, L Duhamel, K Stone, ... Journal of Chromatography A 1643, 462008, 2021 | 17 | 2021 |
| Ion exchange chromatographic behavior of a homologous cytochrome C variant library obtained by controlled succinylation WK Chung, MA Holstein, AS Freed, ST Evans, ZC Baer, SM Cramer Separation Science and Technology 45 (15), 2144-2152, 2010 | 14 | 2010 |
| Antibody retention by virus filtration membranes: Polarization and sieving effects M Billups, M Minervini, M Holstein, H Feroz, S Ranjan, J Hung, H Bao, ... Journal of Membrane Science 620, 118884, 2021 | 13 | 2021 |
| Protein A intermediate wash strategies M Holstein, K Cotoni, N Bian BioProcess Int 13 (2), 2015 | 11 | 2015 |
| Role of membrane structure on the filtrate flux during monoclonal antibody filtration through virus retentive membranes M Billups, M Minervini, M Holstein, H Feroz, S Ranjan, J Hung, H Bao, ... Biotechnology progress 38 (2), e3231, 2022 | 10 | 2022 |
| Process analytical technology for on‐line monitoring of quality attributes during single‐use ultrafiltration/diafiltration JM West, H Feroz, X Xu, N Puri, M Holstein, S Ghose, J Ding, ZJ Li Biotechnology and Bioengineering 118 (6), 2293-2300, 2021 | 9 | 2021 |
| Physiochemical properties of enveloped viruses and arginine dictate inactivation CL Meingast, PU Joshi, DG Turpeinen, X Xu, M Holstein, H Feroz, ... Biotechnology Journal 16 (7), 2000342, 2021 | 8 | 2021 |
| Detection of trace proteins in multicomponent mixtures using displacement chromatography ST Evans, M Holstein, SM Cramer Analytical chemistry 83 (11), 4184-4192, 2011 | 8 | 2011 |
| Virus inactivation at moderately low pH varies with virus and buffer properties PU Joshi, CL Meingast, X Xu, M Holstein, H Feroz, S Ranjan, S Ghose, ... Biotechnology Journal 17 (2), 2100320, 2022 | 7 | 2022 |
