Anti-methicillin resistant Staphylococcus aureus activity, synergism with oxacillin and molecular docking studies of metronidazole-triazole hybrids B Negi, D Kumar, W Kumbukgolla, S Jayaweera, P Ponnan, R Singh, ... European Journal of Medicinal Chemistry 115, 426-437, 2016 | 51 | 2016 |
Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin–antitoxin system: targeting a tRNase to tackle … A Deep, P Tiwari, S Agarwal, S Kaundal, S Kidwai, R Singh, KG Thakur Nucleic acids research 46 (21), 11639-11655, 2018 | 41 | 2018 |
Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis M Singh, P Tiwari, G Arora, S Agarwal, S Kidwai, R Singh Scientific reports 6 (1), 26900, 2016 | 41 | 2016 |
System-wide analysis unravels the differential regulation and in vivo essentiality of virulence-associated proteins B and C toxin-antitoxin systems of Mycobacterium tuberculosis S Agarwal, P Tiwari, A Deep, S Kidwai, S Gupta, KG Thakur, R Singh The Journal of Infectious Diseases 217 (11), 1809-1820, 2018 | 37 | 2018 |
VapBC22 toxin-antitoxin system from Mycobacterium tuberculosis is required for pathogenesis and modulation of host immune response S Agarwal, A Sharma, R Bouzeyen, A Deep, H Sharma, ... Science advances 6 (23), eaba6944, 2020 | 34 | 2020 |
Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner S Mawatwal, A Behura, A Ghosh, S Kidwai, A Mishra, A Deep, S Agarwal, ... Biochimica Et Biophysica Acta (BBA)-General Subjects 1861 (12), 3190-3200, 2017 | 33 | 2017 |
VapC21 Toxin Contributes to Drug-Tolerance and Interacts With Non-cognate VapB32 Antitoxin in Mycobacterium tuberculosis A Sharma, G Chattopadhyay, P Chopra, M Bhasin, C Thakur, S Agarwal, ... Frontiers in Microbiology 11, 2037, 2020 | 23 | 2020 |
Crystal structure of Mycobacterium tuberculosis VapC20 toxin and its interactions with cognate antitoxin, VapB20, suggest a model for toxin–antitoxin assembly A Deep, S Kaundal, S Agarwal, R Singh, KG Thakur The FEBS Journal 284 (23), 4066-4082, 2017 | 21 | 2017 |
Inorganic polyphosphate accumulation suppresses the dormancy response and virulence in Mycobacterium tuberculosis P Tiwari, TP Gosain, M Singh, GD Sankhe, G Arora, S Kidwai, S Agarwal, ... Journal of Biological Chemistry 294 (28), 10819-10832, 2019 | 14 | 2019 |
System wide analysis unravels differential regulation and in vivo essentiality of VapBC TA systems from Mycobacterium tuberculosis S Agarwal, P Tiwari, A Deep, S Kidwai, S Gupta, KG Thakur, R Singh The Journal of infectious diseases, 2018 | 6 | 2018 |
Establishing Virulence Associated Polyphosphate Kinase 2 as a drug target for Mycobacterium tuberculosis (June, 10.1038/srep26900, 2016) M Singh, P Tiwari, G Arora, S Agarwal, S Kidwai, R Singh SCIENTIFIC REPORTS 11 (1), 2021 | | 2021 |
Calcimycin induced autophagy decreases mycobacterial growth in THP-1 cells through P2RX7 dependent pathway mediated by intracellular calcium S Mawatwal, A Behura, A Ghosh, S Agarwal, A Mishra, S Kidwai, S Saha, ... | | 2018 |