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Kanika Choughule
Kanika Choughule
Dirección de correo verificada de wsu.edu
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Evaluation of rhesus monkey and guinea pig hepatic cytosol fractions as models for human aldehyde oxidase
KV Choughule, JT Barr, JP Jones
Drug metabolism and disposition 41 (10), 1852-1858, 2013
412013
In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase
KV Choughule, C Barnaba, CA Joswig-Jones, JP Jones
Drug Metabolism and Disposition 42 (8), 1334-1340, 2014
352014
Interspecies differences in the metabolism of methotrexate: an insight into the active site differences between human and rabbit aldehyde oxidase
KV Choughule, CA Joswig-Jones, JP Jones
Biochemical pharmacology 96 (3), 288-295, 2015
342015
Inhibition of xanthine oxidase by the aldehyde oxidase inhibitor raloxifene: implications for identifying molybdopterin nitrite reductases
ER Weidert, SO Schoenborn, N Cantu-Medellin, KV Choughule, JP Jones, ...
Nitric Oxide 37, 41-45, 2014
332014
Why do most human liver cytosol preparations lack xanthine oxidase activity?
JT Barr, KV Choughule, S Nepal, T Wong, AS Chaudhry, ...
Drug metabolism and disposition 42 (4), 695-699, 2014
282014
Enzyme kinetics, inhibition, and regioselectivity of aldehyde oxidase
JT Barr, K Choughule, JP Jones
Enzyme kinetics in drug metabolism: fundamentals and applications, 167-186, 2014
222014
Characterization of bovine phenol sulfotransferases: evidence of a major role for SULT1B1 in the liver
KV Choughule, CW Locuson, MWH Coughtrie
Xenobiotica 45 (6), 495-502, 2015
22015
Enzyme Kinetics, Pharmacokinetics, and Inhibition of Aldehyde Oxidase
EM Paragas, K Choughule, JP Jones, JT Barr
Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications, 257-284, 2021
12021
Evaluation of a pre-constructed relative induction score (RIS) curve for prediction of CYP3A4 induction response in vivo
G Zhang, T Ho, RJ Clark, S Trisdale, K Choughule, L Fox, D Ramsden
Drug Metabolism and Pharmacokinetics 34 (1), S44-S45, 2019
2019
Validation of cocktail enzyme assay in 96-well plated human hepatocytes for CYP1A2, CYP2B6 and CYP3A4 induction studies with LC–MS/MS analysis
KV Choughule, T Ho, D Wang, DM Stresser, SK Trisdale, T Creegan, ...
Drug Metabolism and Pharmacokinetics 33 (1), S61, 2018
2018
Characterisation of the sulfotransferases catalysing the sulfation of xenobiotics and steroids in bovine liver
K Choughule
University of Dundee, 2011
2011
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Artículos 1–11