The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis F Hamaratoglu, M Willecke, M Kango-Singh, R Nolo, E Hyun, C Tao, ... Nature cell biology 8 (1), 27-36, 2006 | 813 | 2006 |
Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling M Acar, H Jafar-Nejad, H Takeuchi, A Rajan, D Ibrani, NA Rana, H Pan, ... Cell 132 (2), 247-258, 2008 | 359 | 2008 |
Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors H Jafar-Nejad, HK Andrews, M Acar, V Bayat, F Wirtz-Peitz, SQ Mehta, ... Developmental cell 9 (3), 351-363, 2005 | 223 | 2005 |
The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins H Tsuda, H Jafar-Nejad, AJ Patel, Y Sun, HK Chen, MF Rose, ... Cell 122 (4), 633-644, 2005 | 216 | 2005 |
Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi R Fernandez-Valdivia, H Takeuchi, A Samarghandi, M Lopez, J Leonardi, ... Development 138 (10), 1925-1934, 2011 | 189 | 2011 |
Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states L LeBon, TV Lee, D Sprinzak, H Jafar-Nejad, MB Elowitz eLife 3, e02950, 2014 | 157 | 2014 |
Senseless acts as a binary switch during sensory organ precursor selection H Jafar-Nejad, M Acar, R Nolo, H Lacin, H Pan, SM Parkhurst, HJ Bellen Genes & development 17 (23), 2966-2978, 2003 | 150 | 2003 |
Freud-1: a neuronal calcium-regulated repressor of the 5-HT1A receptor gene XM Ou, S Lemonde, H Jafar-Nejad, CD Bown, A Goto, A Rogaeva, ... Journal of Neuroscience 23 (19), 7415-7425, 2003 | 134 | 2003 |
Mapping Drosophila mutations with molecularly defined P element insertions RG Zhai, PR Hiesinger, TW Koh, P Verstreken, KL Schulze, Y Cao, ... Proceedings of the National Academy of Sciences 100 (19), 10860-10865, 2003 | 116 | 2003 |
Negative Regulation of Notch Signaling by Xylose TV Lee, MK Sethi, J Leonardi, NA Rana, FFR Buettner, RS Haltiwanger, ... PLoS Genetics 9 (6), e1003547, 2013 | 106 | 2013 |
Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi) SM Thakurdas, MF Lopez, S Kakuda, R Fernandez‐Valdivia, ... Hepatology 63 (2), 550-565, 2016 | 97 | 2016 |
A POGLUT1 mutation causes a muscular dystrophy with reduced Notch signaling and satellite cell loss E Servián‐Morilla, H Takeuchi, TV Lee, J Clarimon, F Mavillard, ... EMBO molecular medicine 8 (11), 1289-1309, 2016 | 96 | 2016 |
Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator M Acar, H Jafar-Nejad, N Giagtzoglou, S Yallampalli, G David, Y He, ... Development 133 (10), 1979-1989, 2006 | 89 | 2006 |
Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase H Takeuchi, RC Fernández-Valdivia, DS Caswell, A Nita-Lazar, NA Rana, ... Proceedings of the National Academy of Sciences 108 (40), 16600-16605, 2011 | 88 | 2011 |
Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling J Leonardi, R Fernandez-Valdivia, YD Li, AA Simcox, H Jafar-Nejad Development 138 (16), 3569-3578, 2011 | 84 | 2011 |
The roles of Notch signaling in liver development and disease JM Adams, H Jafar-Nejad Biomolecules 9 (10), 608, 2019 | 83 | 2019 |
Role of glycans and glycosyltransferases in the regulation of Notch signaling H Jafar-Nejad, J Leonardi, R Fernandez-Valdivia Glycobiology 20 (8), 931-949, 2010 | 82 | 2010 |
Senseless and Daughterless confer neuronal identity to epithelial cells in the Drosophila wing margin H Jafar-Nejad, AC Tien, M Acar, HJ Bellen Development 133 (9), 1683-1692, 2006 | 77 | 2006 |
Novel dual repressor elements for neuronal cell-specific transcription of the rat 5-HT1A receptor gene XM Ou, H Jafar-Nejad, JM Storring, JH Meng, S Lemonde, PR Albert Journal of Biological Chemistry 275 (11), 8161-8168, 2000 | 76 | 2000 |
Mapping sites of O-glycosylation and fringe elongation on Drosophila Notch BM Harvey, NA Rana, H Moss, J Leonardi, H Jafar-Nejad, ... Journal of Biological Chemistry 291 (31), 16348-16360, 2016 | 70 | 2016 |