i j holt
i j holt
Biodonostia Research Institute
Verified email at biodonostia.org
Title
Cited by
Cited by
Year
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
IJ Holt, AE Harding, JA Morgan-Hughes
nature 331 (6158), 717-719, 1988
19961988
A new mitochondrial disease associated with mitochondrial DNA heteroplasmy.
IJ Holt, AE Harding, RK Petty, JA Morgan-Hughes
American journal of human genetics 46 (3), 428, 1990
10871990
Coupled leading-and lagging-strand synthesis of mammalian mitochondrial DNA
IJ Holt, HE Lorimer, HT Jacobs
Cell 100 (5), 515-524, 2000
4862000
Blue Native electrophoresis to study mitochondrial and other protein complexes
LGJ Nijtmans, NS Henderson, IJ Holt
Methods 26 (4), 327-334, 2002
3862002
Mitochondrial myopathies: clinical and biochemical features of 30 patients with major deletions of muscle mitochondrial DNA
IJ Holt, AE Harding, JM Cooper, AHV Schapira, A Toscano, JB Clark, ...
Annals of Neurology: Official Journal of the American Neurological …, 1989
3411989
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development
MAM Reijns, B Rabe, RE Rigby, P Mill, KR Astell, LA Lettice, S Boyle, ...
Cell 149 (5), 1008-1022, 2012
3402012
Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication
MY Yang, M Bowmaker, A Reyes, L Vergani, P Angeli, E Gringeri, ...
Cell 111 (4), 495-505, 2002
3112002
Minimizing the damage: repair pathways keep mitochondrial DNA intact
L Kazak, A Reyes, IJ Holt
Nature reviews Molecular cell biology 13 (10), 659-671, 2012
3052012
Pearson syndrome and mitochondrial encephalomyopathy in a patient with a deletion of mtDNA.
MA McShane, SR Hammans, M Sweeney, IJ Holt, TJ Beattie, EM Brett, ...
American journal of human genetics 48 (1), 39, 1991
2781991
Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand
T Yasukawa, A Reyes, TJ Cluett, MY Yang, M Bowmaker, HT Jacobs, ...
The EMBO journal 25 (22), 5358-5371, 2006
2652006
PrimPol, an archaic primase/polymerase operating in human cells
S García-Gómez, A Reyes, MI Martínez-Jiménez, ES Chocrón, S Mourón, ...
Molecular cell 52 (4), 541-553, 2013
2632013
Mammalian mitochondrial DNA replicates bidirectionally from an initiation zone
M Bowmaker, MY Yang, T Yasukawa, A Reyes, HT Jacobs, JA Huberman, ...
Journal of Biological Chemistry 278 (51), 50961-50969, 2003
2562003
Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number
H Tyynismaa, H Sembongi, M Bokori-Brown, C Granycome, N Ashley, ...
Human molecular genetics 13 (24), 3219-3227, 2004
2382004
Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes
DR Dunbar, PA Moonie, HT Jacobs, IJ Holt
Proceedings of the National Academy of Sciences 92 (14), 6562-6566, 1995
2091995
The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization
J He, CC Mao, A Reyes, H Sembongi, M Di Re, C Granycome, ...
The Journal of cell biology 176 (2), 141-146, 2007
2022007
A bidirectional origin of replication maps to the major noncoding region of human mitochondrial DNA
T Yasukawa, MY Yang, HT Jacobs, IJ Holt
Molecular cell 18 (6), 651-662, 2005
1872005
Genetic heterogeneity and mitochondrial DNA heteroplasmy in Leber's hereditary optic neuropathy.
IJ Holt, DH Miller, AE Harding
Journal of medical genetics 26 (12), 739-743, 1989
1821989
Human mitochondrial DNA replication
IJ Holt, A Reyes
Cold Spring Harbor perspectives in biology 4 (12), a012971, 2012
1712012
Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication
JM Fusté, S Wanrooij, E Jemt, CE Granycome, TJ Cluett, Y Shi, ...
Molecular cell 37 (1), 67-78, 2010
1712010
Mammalian mitochondrial nucleoids: organizing an independently minded genome
IJ Holt, J He, CC Mao, JD Boyd-Kirkup, P Martinsson, H Sembongi, ...
Mitochondrion 7 (5), 311-321, 2007
1712007
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