Wayne Chen
Wayne Chen
Afiliació desconeguda
Correu electrònic verificat a ucalgary.ca
Citada per
Citada per
RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR)
D Jiang, B Xiao, D Yang, R Wang, P Choi, L Zhang, H Cheng, SRW Chen
Proceedings of the National Academy of Sciences 101 (35), 13062-13067, 2004
Inherited Dysfunction of Sarcoplasmic Reticulum Ca2+ Handling and Arrhythmogenesis
SG Priori, SRW Chen
Circulation research 108 (7), 871-883, 2011
Dantrolene inhibition of ryanodine receptor Ca2+ release channels: molecular mechanism and isoform selectivity
F Zhao, P Li, SRW Chen, CF Louis, BR Fruen
Journal of Biological Chemistry 276 (17), 13810-13816, 2001
Enhanced Store Overload–Induced Ca2+ Release and Channel Sensitivity to Luminal Ca2+ Activation Are Common Defects of RyR2 Mutations Linked to …
D Jiang, R Wang, B Xiao, H Kong, DJ Hunt, P Choi, L Zhang, SRW Chen
Circulation research 97 (11), 1173-1181, 2005
Enhanced Basal Activity of a Cardiac Ca2+ Release Channel (Ryanodine Receptor) Mutant Associated With Ventricular Tachycardia and Sudden Death
D Jiang, B Xiao, L Zhang, SRW Chen
Circulation research 91 (3), 218-225, 2002
Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure
B Xiao, MT Jiang, M Zhao, D Yang, C Sutherland, FA Lai, MP Walsh, ...
Circulation research 96 (8), 847-855, 2005
Molecular identification of the ryanodine receptor pore-forming segment
M Zhao, P Li, X Li, L Zhang, RJ Winkfein, SRW Chen
Journal of Biological Chemistry 274 (37), 25971-25974, 1999
Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca 2+ release
Q Zhou, J Xiao, D Jiang, R Wang, K Vembaiyan, A Wang, CD Smith, C Xie, ...
Nature medicine 17 (8), 1003-1009, 2011
Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon β-adrenergic stimulation in normal …
B Xiao, G Zhong, M Obayashi, D Yang, K Chen, MP Walsh, Y Shimoni, ...
Biochemical Journal 396 (1), 7-16, 2006
Protein Kinase A Phosphorylation at Serine-2808 of the Cardiac Ca2+-Release Channel (Ryanodine Receptor) Does Not Dissociate 12.6-kDa FK506-Binding …
B Xiao, C Sutherland, MP Walsh, SRW Chen
Circulation research 94 (4), 487-495, 2004
Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2
W Peng, H Shen, J Wu, W Guo, X Pan, R Wang, SRW Chen, N Yan
Science 354 (6310), 2016
Functional characterization of the recombinant type 3 Ca2+ release channel (ryanodine receptor) expressed in HEK293 cells
SRW Chen, X Li, K Ebisawa, L Zhang
Journal of Biological Chemistry 272 (39), 24234-24246, 1997
Caffeine induces Ca2+ release by reducing the threshold for luminal Ca2+ activation of the ryanodine receptor
H Kong, PP Jones, A Koop, L Zhang, HJ Duff, SRW Chen
Biochemical Journal 414 (3), 441-452, 2008
The ryanodine receptor store-sensing gate controls Ca 2+ waves and Ca 2+-triggered arrhythmias
W Chen, R Wang, B Chen, X Zhong, H Kong, Y Bai, Q Zhou, C Xie, ...
Nature medicine 20 (2), 184-192, 2014
Molecular identification of the ryanodine receptor Ca2+ sensor
SRW Chen, K Ebisawa, X Li, L Zhang
Journal of Biological Chemistry 273 (24), 14675-14678, 1998
Molecular Basis of Ca2+ Activation of the Mouse Cardiac Ca2+ Release Channel (Ryanodine Receptor)
P Li, SRW Chen
The Journal of general physiology 118 (1), 33-44, 2001
Divergent functional properties of ryanodine receptor types 1 and 3 expressed in a myogenic cell line
JD Fessenden, Y Wang, RA Moore, SRW Chen, PD Allen, IN Pessah
Biophysical Journal 79 (5), 2509-2525, 2000
Loss of luminal Ca2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death
D Jiang, W Chen, R Wang, L Zhang, SRW Chen
Proceedings of the National Academy of Sciences 104 (46), 18309-18314, 2007
PI3Kγ is required for PDE4, not PDE3, activity in subcellular microdomains containing the sarcoplasmic reticular calcium ATPase in cardiomyocytes
BG Kerfant, D Zhao, I Lorenzen-Schmidt, LS Wilson, S Cai, SRW Chen, ...
Circulation research 101 (4), 400-408, 2007
Localization of the 12.6-kDa FK506-binding protein (FKBP12. 6) binding site to the NH2-terminal domain of the cardiac Ca2+ release channel (ryanodine receptor)
H Masumiya, R Wang, J Zhang, B Xiao, SRW Chen
Journal of Biological Chemistry 278 (6), 3786-3792, 2003
En aquests moments el sistema no pot dur a terme l'operació. Torneu-ho a provar més tard.
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