| Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells D Li, ND Marchenko, R Schulz, V Fischer, T Velasco-Hernandez, F Talos, ... Molecular Cancer Research 9 (5), 577-588, 2011 | 317 | 2011 |
| Metabolic and innate immune cues merge into a specific inflammatory response via the UPR DA Mogilenko, JT Haas, L L’homme, S Fleury, S Quemener, ... Cell 177 (5), 1201-1216. e19, 2019 | 126 | 2019 |
| HIF-1α can act as a tumor suppressor gene in murine acute myeloid leukemia T Velasco-Hernandez, A Hyrenius-Wittsten, M Rehn, D Bryder, ... Blood, The Journal of the American Society of Hematology 124 (24), 3597-3607, 2014 | 110 | 2014 |
| Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia D Sánchez-Martínez, ML Baroni, F Gutierrez-Agüera, H Roca-Ho, ... Blood, The Journal of the American Society of Hematology 133 (21), 2291-2304, 2019 | 97 | 2019 |
| Potential pitfalls of the Mx1-Cre system: implications for experimental modeling of normal and malignant hematopoiesis T Velasco-Hernandez, P Säwén, D Bryder, J Cammenga Stem cell reports 7 (1), 11-18, 2016 | 74 | 2016 |
| 41BB-based and CD28-based CD123-redirected T-cells ablate human normal hematopoiesis in vivo ML Baroni, DS Martinez, FG Aguera, HR Ho, M Castella, SR Zanetti, ... Journal for immunotherapy of cancer 8 (1), 2020 | 42 | 2020 |
| Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells M Eriksson, P Peña-Martínez, R Ramakrishnan, M Chapellier, C Högberg, ... Blood advances 1 (23), 2046-2057, 2017 | 42 | 2017 |
| CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity C Bueno, T Velasco-Hernandez, F Gutiérrez-Agüera, SR Zanetti, ... Leukemia 33 (8), 2090-2125, 2019 | 38 | 2019 |
| Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells YW Zhang, J Mess, N Aizarani, P Mishra, C Johnson, MC Romero-Mulero, ... Nature cell biology 24 (7), 1038-1048, 2022 | 35 | 2022 |
| Deregulation of genes related to iron and mitochondrial metabolism in refractory anemia with ring sideroblasts M del Rey, R Benito, C Fontanillo, FJ Campos-Laborie, K Janusz, ... PLoS One 10 (5), e0126555, 2015 | 32 | 2015 |
| A novel and efficient tandem CD19-and CD22-directed CAR for B cell ALL SR Zanetti, T Velasco-Hernandez, F Gutierrez-Agüera, VM Díaz, ... Molecular Therapy 30 (2), 550-563, 2022 | 27 | 2022 |
| p53 restoration kills primitive leukemia cells in vivo and increases survival of leukemic mice T Velasco-Hernández, C Vicente-Dueñas, I Sánchez-García, ... Cell Cycle 12 (1), 122-132, 2013 | 23 | 2013 |
| Loss of HIF-1α accelerates murine FLT-3ITD-induced myeloproliferative neoplasia T Velasco-Hernandez, D Tornero, J Cammenga Leukemia 29 (12), 2366-2374, 2015 | 22 | 2015 |
| Hif-1Α deletion may lead to adverse treatment effect in a mouse model of Mll-Af9-driven aml T Velasco-Hernandez, S Soneji, I Hidalgo, E Erlandsson, J Cammenga, ... Stem cell reports 12 (1), 112-121, 2019 | 21 | 2019 |
| Distinct roles for PARP-1 and PARP-2 in c-Myc–driven B-cell lymphoma in mice MA Galindo-Campos, N Lutfi, S Bonnin, C Martínez, ... Blood, The Journal of the American Society of Hematology 139 (2), 228-239, 2022 | 17 | 2022 |
| The “Never-Ending” mouse models for MLL-rearranged acute leukemia are still teaching Us K Ottersbach, A Sanjuan-Pla, R Torres-Ruíz, C Bueno, ... HemaSphere 2 (4), e57, 2018 | 12 | 2018 |
| Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope T Velasco-Hernandez, SR Zanetti, H Roca-Ho, F Gutierrez-Aguera, ... Journal for immunotherapy of cancer 8 (2), 2020 | 10 | 2020 |
| Engraftment characterization of risk-stratified AML in NSGS mice R Díaz de la Guardia, T Velasco-Hernandez, F Gutiérrez-Agüera, ... Blood advances 5 (23), 4842-4854, 2021 | 9 | 2021 |
| Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia P Jaako, A Ugale, M Wahlestedt, T Velasco-Hernandez, J Cammenga, ... Leukemia 31 (1), 213-221, 2017 | 7 | 2017 |
| Opportunities for CAR-T Cell Immunotherapy in HIV Cure G Campos-Gonzalez, J Martinez-Picado, T Velasco-Hernandez, ... Viruses 15 (3), 789, 2023 | 5 | 2023 |
Heleia Roca-HoPostdoctoral ScientistVerified email at carrerasresearch.org
