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Laura Pellegrini
Laura Pellegrini
Group Leader, King's College London
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF barrier in human brain organoids
L Pellegrini, A Albecka, DL Mallery, MJ Kellner, D Paul, AP Carter, ...
Cell stem cell 27 (6), 951-961. e5, 2020
4582020
Human CNS barrier-forming organoids with cerebrospinal fluid production
L Pellegrini, C Bonfio, J Chadwick, F Begum, M Skehel, MA Lancaster
Science 369 (6500), eaaz5626, 2020
2882020
Back to the tubule: microtubule dynamics in Parkinson’s disease
L Pellegrini, A Wetzel, S Grannó, G Heaton, K Harvey
Cellular and Molecular Life Sciences 74, 409-434, 2017
1382017
The Parkinson’s disease protein LRRK2 interacts with the GARP complex to promote retrograde transport to the trans-Golgi network
A Beilina, L Bonet-Ponce, R Kumaran, JJ Kordich, M Ishida, A Mamais, ...
Cell reports 31 (5), 2020
622020
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice
L Pellegrini, DN Hauser, Y Li, A Mamais, A Beilina, R Kumaran, A Wetzel, ...
Human molecular genetics 27 (18), 3257-3271, 2018
612018
Androgens increase excitatory neurogenic potential in human brain organoids
I Kelava, I Chiaradia, L Pellegrini, AT Kalinka, MA Lancaster
Nature 602 (7895), 112-116, 2022
572022
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ...
PLoS biology 19 (12), e3001480, 2021
512021
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis
GR Heaton, N Landeck, A Mamais, MA Nalls, J Nixon-Abell, R Kumaran, ...
Neurobiology of disease 141, 104948, 2020
292020
Human CNS barrier-forming organoids with cerebrospinal fluid production. Science 369, eaaz5626
L Pellegrini, C Bonfio, J Chadwick, F Begum, M Skehel, MA Lancaster
152020
Modeling neurodegeneration with mutant-tau organoids
L Pellegrini, MA Lancaster
Cell 184 (17), 4377-4379, 2021
102021
Tissue morphology influences the temporal program of human brain organoid development
I Chiaradia, I Imaz-Rosshandler, BS Nilges, J Boulanger, L Pellegrini, ...
Cell stem cell 30 (10), 1351-1367. e10, 2023
82023
Breaking the barrier: In vitro models to study choroid plexus development
L Pellegrini, MA Lancaster
Current Opinion in Cell Biology 73, 41-49, 2021
62021
Pathogenic mutations in LRRK2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
A Mamais, N Landeck, RG Langston, L Bonet-Ponce, N Smith, A Beilina, ...
52020
SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier
L Pellegrine, A Albecka, DL Mallery
medRxiv, 2020
32020
Male sex hormones increase excitatory neuron production in developing human neocortex
I Kelava, I Chiaradia, L Pellegrini, AT Kalinka, MA Lancaster
bioRxiv, 2020.10. 24.353359, 2020
22020
Choroid plexus protein turnover in human choroid plexus organoids recapitulates turnover in humans measured using stable isotope labeling kinetics (SILK)
TA Giovannucci, CA Leckey, E Moncur, K Tariq, L Thorne, L Watkins, ...
Alzheimer's & Dementia 19, e074240, 2023
12023
Desensitization Protocols for Anti-SARS-CoV-2 Vaccines in Patients with High Risk of Allergic Reactions
MR Messina, C Crisciotti, L Pellegrini, E Nappi, F Racca, G Costanzo, ...
Vaccines 11 (5), 910, 2023
12023
Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ...
Plos Biology 20 (5), e3001621, 2022
12022
Choroid plexus organoids and methods for production thereof
MA Lancaster, L Pellegrini
US Patent App. 17/425,043, 2022
12022
Pathogenic mutations in leucine-rich repeat kinase 2 sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
A Mamais, N Landeck, RG Langston, L Bonet-Ponce, N Smith, A Beilina, ...
bioRxiv, 2020.07. 27.219501, 2020
12020
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