The fibronectin type III domain as a scaffold for novel binding proteins A Koide, CW Bailey, X Huang, S Koide Journal of molecular biology 284 (4), 1141-1151, 1998 | 802 | 1998 |
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide AK Shukla, A Manglik, AC Kruse, K Xiao, RI Reis, WC Tseng, DP Staus, ... Nature 497 (7447), 137-141, 2013 | 461 | 2013 |
High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries FA Fellouse, K Esaki, S Birtalan, D Raptis, VJ Cancasci, A Koide, ... Journal of molecular biology 373 (4), 924-940, 2007 | 449 | 2007 |
Molecular mechanism of thioflavin-T binding to the surface of β-rich peptide self-assemblies M Biancalana, K Makabe, A Koide, S Koide Journal of molecular biology 385 (4), 1052-1063, 2009 | 390 | 2009 |
Inhibition of RAS function through targeting an allosteric regulatory site R Spencer-Smith, A Koide, Y Zhou, RR Eguchi, F Sha, P Gajwani, ... Nature chemical biology 13 (1), 62-68, 2017 | 276 | 2017 |
Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold A Koide, J Wojcik, RN Gilbreth, RJ Hoey, S Koide Journal of molecular biology 415 (2), 393-405, 2012 | 244 | 2012 |
High-affinity single-domain binding proteins with a binary-code interface A Koide, RN Gilbreth, K Esaki, V Tereshko, S Koide Proceedings of the National Academy of Sciences 104 (16), 6632-6637, 2007 | 238 | 2007 |
A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain J Wojcik, O Hantschel, F Grebien, I Kaupe, KL Bennett, J Barkinge, ... Nature structural & molecular biology 17 (4), 519-527, 2010 | 200 | 2010 |
CDR-H3 diversity is not required for antigen recognition by synthetic antibodies H Persson, W Ye, A Wernimont, JJ Adams, A Koide, S Koide, R Lam, ... Journal of molecular biology 425 (4), 803-811, 2013 | 185 | 2013 |
Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor A Koide, S Abbatiello, L Rothgery, S Koide Proceedings of the National Academy of Sciences 99 (3), 1253-1258, 2002 | 179 | 2002 |
Structures of a Na+-coupled, substrate-bound MATE multidrug transporter M Lu, J Symersky, M Radchenko, A Koide, Y Guo, R Nie, S Koide Proceedings of the National Academy of Sciences 110 (6), 2099-2104, 2013 | 174 | 2013 |
Monobodies: antibody mimics based on the scaffold of the fibronectin type III domain A Koide, S Koide Protein Engineering Protocols, 95-109, 2007 | 171 | 2007 |
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis F Grebien, O Hantschel, J Wojcik, I Kaupe, B Kovacic, AM Wyrzucki, ... Cell 147 (2), 306-319, 2011 | 169 | 2011 |
SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling C Fedele, S Li, KW Teng, CJR Foster, D Peng, H Ran, P Mita, MJ Geer, ... Journal of Experimental Medicine 218 (1), e20201414, 2020 | 162 | 2020 |
Synthetic antibodies for specific recognition and crystallization of structured RNA JD Ye, V Tereshko, JK Frederiksen, A Koide, FA Fellouse, SS Sidhu, ... Proceedings of the National Academy of Sciences 105 (1), 82-87, 2008 | 151 | 2008 |
Exploring the potential of the monobody scaffold: effects of loop elongation on the stability of a fibronectin type III domain V Batori, A Koide, S Koide Protein engineering 15 (12), 1015-1020, 2002 | 149 | 2002 |
Engineered fibronectin type III domain with a RGDWXE sequence binds with enhanced affinity and specificity to human αvβ3 integrin J Richards, M Miller, J Abend, A Koide, S Koide, S Dewhurst Journal of molecular biology 326 (5), 1475-1488, 2003 | 148 | 2003 |
Stabilization of a fibronectin type III domain by the removal of unfavorable electrostatic interactions on the protein surface A Koide, MR Jordan, SR Horner, V Batori, S Koide Biochemistry 40 (34), 10326-10333, 2001 | 143 | 2001 |
Crystal structures of a double-barrelled fluoride ion channel RB Stockbridge, L Kolmakova-Partensky, T Shane, A Koide, S Koide, ... Nature 525 (7570), 548-551, 2015 | 135 | 2015 |
Design of protein function leaps by directed domain interface evolution J Huang, A Koide, K Makabe, S Koide Proceedings of the National Academy of Sciences 105 (18), 6578-6583, 2008 | 132 | 2008 |