J. Michael McCaffery, Research Professor and Director
J. Michael McCaffery, Research Professor and Director
Johns Hopkins University and Integrated Imaging Center
Verified email at jhu.edu - Homepage
Cited by
Cited by
Fluorescent indicators for Ca 2+ based on green fluorescent proteins and calmodulin
A Miyawaki, J Llopis, R Heim, JM McCaffery, JA Adams, M Ikura, RY Tsien
Nature 388 (6645), 882-887, 1997
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
J Llopis, JM McCaffery, A Miyawaki, MG Farquhar, RY Tsien
Proceedings of the National Academy of Sciences 95 (12), 6803-6808, 1998
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
H Chen, M Vermulst, YE Wang, A Chomyn, TA Prolla, JM McCaffery, ...
Cell 141 (2), 280-289, 2010
Structural basis of mitochondrial tethering by mitofusin complexes
T Koshiba, SA Detmer, JT Kaiser, H Chen, JM McCaffery, DC Chan
Science 305 (5685), 858-862, 2004
Mitochondrial fusion protects against neurodegeneration in the cerebellum
H Chen, JM McCaffery, DC Chan
Cell 130 (3), 548-562, 2007
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast
W Bleazard, JM McCaffery, EJ King, S Bale, A Mozdy, Q Tieu, J Nunnari, ...
Nature cell biology 1 (5), 298-304, 1999
A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast
MNJ Seaman, J Michael McCaffery, SD Emr
The Journal of cell biology 142 (3), 665-681, 1998
Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p
AD Mozdy, JM McCaffery, JM Shaw
The Journal of cell biology 151 (2), 367-380, 2000
TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity
BS Johnson, D Snead, JJ Lee, JM McCaffery, J Shorter, AD Gitler
Journal of Biological Chemistry 284 (30), 20329-20339, 2009
Dnm1 forms spirals that are structurally tailored to fit mitochondria
E Ingerman, EM Perkins, M Marino, JA Mears, JM McCaffery, JE Hinshaw, ...
The Journal of cell biology 170 (7), 1021-1027, 2005
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
P Onyango, I Celic, JM McCaffery, JD Boeke, AP Feinberg
Proceedings of the National Academy of Sciences 99 (21), 13653-13658, 2002
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis
AD Gitler, BJ Bevis, J Shorter, KE Strathearn, S Hamamichi, LJ Su, ...
Proceedings of the National Academy of Sciences 105 (1), 145-150, 2008
Mitochondrial fusion intermediates revealed in vitro
S Meeusen, JM McCaffery, J Nunnari
Science 305 (5691), 1747-1752, 2004
Mitochondrial inner-membrane fusion and crista maintenance requires the dynamin-related GTPase Mgm1
S Meeusen, R DeVay, J Block, A Cassidy-Stone, S Wayson, JM McCaffery, ...
Cell 127 (2), 383-395, 2006
Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion
Z Song, M Ghochani, JM McCaffery, TG Frey, DC Chan
Molecular biology of the cell 20 (15), 3525-3532, 2009
Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum
WE Balch, JM McCaffery, H Plutner, MG Farquhar
Cell 76 (5), 841-852, 1994
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
J Zhang, I Khvorostov, JS Hong, Y Oktay, L Vergnes, E Nuebel, ...
The EMBO journal 30 (24), 4860-4873, 2011
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
BS Johnson, JM McCaffery, S Lindquist, AD Gitler
Proceedings of the National Academy of Sciences 105 (17), 6439-6444, 2008
Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription
H Takahashi, JM McCaffery, RA Irizarry, JD Boeke
Molecular cell 23 (2), 207-217, 2006
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria
ED Wong, JA Wagner, SW Gorsich, JM McCaffery, JM Shaw, J Nunnari
The Journal of cell biology 151 (2), 341-352, 2000
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