| Acetylation of the p53 DNA-binding domain regulates apoptosis induction SM Sykes, HS Mellert, MA Holbert, K Li, R Marmorstein, WS Lane, ... Molecular cell 24 (6), 841-851, 2006 | 857 | 2006 |
| The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression XY Zhang, M Varthi, SM Sykes, C Phillips, C Warzecha, W Zhu, A Wyce, ... Molecular cell 29 (1), 102-111, 2008 | 498 | 2008 |
| The p53 family and programmed cell death EC Pietsch, SM Sykes, SB McMahon, ME Murphy Oncogene 27 (50), 6507-6521, 2008 | 429 | 2008 |
| Diabetes impairs hematopoietic stem cell mobilization by altering niche function F Ferraro, S Lymperi, S Méndez-Ferrer, B Saez, JA Spencer, BY Yeap, ... Science translational medicine 3 (104), 104ra101-104ra101, 2011 | 345 | 2011 |
| AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias SM Sykes, SW Lane, L Bullinger, D Kalaitzidis, R Yusuf, B Saez, F Ferraro, ... Cell 146 (5), 697-708, 2011 | 297 | 2011 |
| Requirement for CDK6 in MLL-rearranged acute myeloid leukemia T Placke, K Faber, A Nonami, SL Putwain, HR Salih, FH Heidel, A Krämer, ... Blood, The Journal of the American Society of Hematology 124 (1), 13-23, 2014 | 211 | 2014 |
| mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis D Kalaitzidis, SM Sykes, Z Wang, N Punt, Y Tang, C Ragu, AU Sinha, ... Cell stem cell 11 (3), 429-439, 2012 | 197 | 2012 |
| Menin associates with FANCD2, a protein involved in repair of DNA damage S Jin, H Mao, RW Schnepp, SM Sykes, AC Silva, AD D’Andrea, X Hua Cancer research 63 (14), 4204-4210, 2003 | 197 | 2003 |
| Differential niche and Wnt requirements during acute myeloid leukemia progression SW Lane, YJ Wang, C Lo Celso, C Ragu, L Bullinger, SM Sykes, ... Blood, The Journal of the American Society of Hematology 118 (10), 2849-2856, 2011 | 177 | 2011 |
| Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1 K Parmar, J Kim, SM Sykes, A Shimamura, P Stuckert, K Zhu, A Hamilton, ... Stem cells 28 (7), 1186-1195, 2010 | 126 | 2010 |
| The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS SW Lane, SM Sykes, F Al-Shahrour, S Shterental, M Paktinat, C Lo Celso, ... Blood, The Journal of the American Society of Hematology 115 (17), 3489-3497, 2010 | 121 | 2010 |
| The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS SW Lane, SM Sykes, F Al-Shahrour, S Shterental, M Paktinat, C Lo Celso, ... Blood, The Journal of the American Society of Hematology 115 (17), 3489-3497, 2010 | 121 | 2010 |
| Acetylation of the DNA binding domain regulates transcription-independent apoptosis by p53 SM Sykes, TJ Stanek, A Frank, ME Murphy, SB McMahon Journal of Biological Chemistry 284 (30), 20197-20205, 2009 | 109 | 2009 |
| Menin induces apoptosis in murine embryonic fibroblasts RW Schnepp, H Mao, SM Sykes, WX Zong, A Silva, P La, X Hua Journal of Biological Chemistry 279 (11), 10685-10691, 2004 | 87 | 2004 |
| BRCA1 mutation-specific responses to 53BP1 loss-induced homologous recombination and PARP inhibitor resistance J Nacson, JJ Krais, AJ Bernhardy, E Clausen, W Feng, Y Wang, E Nicolas, ... Cell reports 24 (13), 3513-3527. e7, 2018 | 85 | 2018 |
| Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification MG Cornejo, V Mabialah, SM Sykes, T Khandan, C Lo Celso, CK Lopez, ... Blood, The Journal of the American Society of Hematology 118 (5), 1264-1273, 2011 | 76 | 2011 |
| mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition JJ Limon, L So, S Jellbauer, H Chiu, J Corado, SM Sykes, M Raffatellu, ... Proceedings of the National Academy of Sciences 111 (47), E5076-E5085, 2014 | 71 | 2014 |
| Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells M Nieborowska-Skorska, K Sullivan, Y Dasgupta, ... The Journal of clinical investigation 127 (6), 2392-2406, 2017 | 70 | 2017 |
| Tyrosine kinase inhibitor–induced defects in DNA repair sensitize FLT3 (ITD)-positive leukemia cells to PARP1 inhibitors S Maifrede, M Nieborowska-Skorska, K Sullivan-Reed, Y Dasgupta, ... Blood, The Journal of the American Society of Hematology 132 (1), 67-77, 2018 | 66 | 2018 |
| RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia S Rudat, A Pfaus, YY Cheng, J Holtmann, JM Ellegast, C Buehler, ... Leukemia 32 (10), 2189-2202, 2018 | 63 | 2018 |
