Submarine groundwater discharge to Great South Bay, NY, estimated using Ra isotopes AJ Beck, JP Rapaglia, JK Cochran, HJ Bokuniewicz, S Yang Marine Chemistry 109 (3), 279-291, 2008 | 66 | 2008 |
Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors SH Yang, DB Khadka, SH Cho, HK Ju, KY Lee, HJ Han, KT Lee, WJ Cho Bioorganic & Medicinal Chemistry 19 (2), 968-977, 2011 | 60 | 2011 |
Discovery and Mechanistic Elucidation of a Class of Protein Disulfide Isomerase Inhibitors for the Treatment of Glioblastoma A Kyani, S Tamura, S Yang, A Shergalis, S Samanta, Y Kuang, ... ChemMedChem 13 (2), 164-177, 2018 | 57 | 2018 |
The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress–Mediated Apoptosis in Pancreatic Cancer S Samanta, S Yang, B Debnath, D Xue, Y Kuang, K Ramkumar, AS Lee, ... Cancer Research 81 (7), 1883-1895, 2021 | 56 | 2021 |
Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor K Ramkumar, S Samanta, A Kyani, S Yang, S Tamura, E Ziemke, ... Nature Communications 7, 2016 | 56 | 2016 |
Molecular design, synthesis and docking study of benz [b] oxepines and 12-oxobenzo [c] phenanthridinones as topoisomerase 1 inhibitors SH Lee, HTM Van, SH Yang, KT Lee, Y Kwon, WJ Cho Bioorganic & medicinal chemistry letters 19 (9), 2444-2447, 2009 | 50 | 2009 |
Structure-based virtual screening and identification of a novel androgen receptor antagonist CH Song, SH Yang, E Park, SH Cho, EY Gong, DB Khadka, WJ Cho, ... Journal of Biological Chemistry 287 (36), 30769-30780, 2012 | 44 | 2012 |
Inhibition of protein disulfide isomerase in glioblastoma causes marked downregulation of DNA repair and DNA damage response genes S Xu, Y Liu, K Yang, H Wang, A Shergalis, A Kyani, A Bankhead III, ... Theranostics 9 (8), 2282, 2019 | 38 | 2019 |
SAR based design of nicotinamides as a novel class of androgen receptor antagonists for prostate cancer SH Yang, CH Song, HTM Van, E Park, DB Khadka, EY Gong, K Lee, ... Journal of medicinal chemistry 56 (8), 3414-3418, 2013 | 33 | 2013 |
Synthesis of 12-oxobenzo [c] phenanthridinones and 4-substituted 3-arylisoquinolones via Vilsmeier–Haack reaction DB Khadka, SH Yang, SH Cho, C Zhao, WJ Cho Tetrahedron 68 (1), 250-261, 2012 | 31 | 2012 |
Synthesis, in vitro and in vivo evaluation of 3-arylisoquinolinamines as potent antitumor agents SH Yang, HTM Van, TN Le, DB Khadka, SH Cho, KT Lee, HJ Chung, ... Bioorganic & medicinal chemistry letters 20 (17), 5277-5281, 2010 | 31 | 2010 |
Total synthesis of 8-oxypseudopalmatine and 8-oxypseudoberberine via ring-closing metathesis HTM Van, SH Yang, DB Khadka, YC Kim, WJ Cho Tetrahedron 65 (49), 10142-10148, 2009 | 31 | 2009 |
Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors HTM Van, H Woo, HM Jeong, DB Khadka, SH Yang, C Zhao, Y Jin, ... European journal of medicinal chemistry 82, 181-194, 2014 | 28 | 2014 |
Development of 3-aryl-1-isoquinolinamines as potent antitumor agents based on CoMFA SH Yang, HTM Van, TN Le, DB Khadka, SH Cho, KT Lee, ES Lee, YB Lee, ... European journal of medicinal chemistry 45 (11), 5493-5497, 2010 | 27 | 2010 |
Design, synthesis, and biological evaluation of novel allosteric protein disulfide isomerase inhibitors S Yang, A Shergalis, D Lu, A Kyani, Z Liu, M Ljungman, N Neamati Journal of medicinal chemistry 62 (7), 3447-3474, 2019 | 26 | 2019 |
Modification of 3-arylisoquinolines into 3, 4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition DB Khadka, H Woo, SH Yang, C Zhao, Y Jin, TN Le, Y Kwon, WJ Cho European journal of medicinal chemistry 92, 583-607, 2015 | 26 | 2015 |
Time-series sampling of 223Ra and 224Ra at the inlet to Great South Bay (New York): a strategy for characterizing the dominant terms in the Ra budget of the bay J Garcia-Orellana, JK Cochran, H Bokuniewicz, S Yang, AJ Beck Journal of environmental radioactivity 101 (7), 582-588, 2010 | 24 | 2010 |
Structure-Based Discovery of Novel Cyclophilin A Inhibitors for the Treatment of Hepatitis C Virus Infections S Yang, S Lim, TG Choi, JH Kim, S Akter, M Jang, HJ Ahn, HY Kim, ... Journal of medicinal chemistry 58 (24), 9546-9561, 2015 | 21 | 2015 |
Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling TN Le, SH Yang, DB Khadka, HTM Van, SH Cho, Y Kwon, ES Lee, ... Bioorganic & medicinal chemistry 19 (14), 4399-4404, 2011 | 19 | 2011 |
Synthesis of benzo [3, 4] azepino [1, 2-b] isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity … HTM Van, DB Khadka, SH Yang, TN Le, SH Cho, C Zhao, IS Lee, Y Kwon, ... Bioorganic & medicinal chemistry 19 (18), 5311-5320, 2011 | 17 | 2011 |