| High Frequency of Mutations of the PIK3CA Gene in Human Cancers Y Samuels, Z Wang, A Bardelli, N Silliman, J Ptak, S Szabo, H Yan, ... Science 304 (5670), 554-554, 2004 | 4282 | 2004 |
| PUMA mediates the apoptotic response to p53 in colorectal cancer cells J Yu, Z Wang, KW Kinzler, B Vogelstein, L Zhang Proceedings of the National Academy of Sciences 100 (4), 1931-1936, 2003 | 734 | 2003 |
| Mutational analysis of the tyrosine phosphatome in colorectal cancers Z Wang, D Shen, DW Parsons, A Bardelli, J Sager, S Szabo, J Ptak, ... Science 304 (5674), 1164-1166, 2004 | 645 | 2004 |
| microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells P Wang, F Zou, X Zhang, H Li, A Dulak, RJ Tomko Jr, JS Lazo, Z Wang, ... Cancer research 69 (20), 8157-8165, 2009 | 358 | 2009 |
| Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes J Yang, J Huang, M Dasgupta, N Sears, M Miyagi, B Wang, MR Chance, ... Proceedings of the National Academy of Sciences 107 (50), 21499-21504, 2010 | 357 | 2010 |
| DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination Z Du, J Song, Y Wang, Y Zhao, K Guda, S Yang, HY Kao, Y Xu, J Willis, ... Science signaling 3 (146), ra80-ra80, 2010 | 357 | 2010 |
| Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration Y Zhang, A Desai, SY Yang, KB Bae, MI Antczak, SP Fink, S Tiwari, ... Science 348 (6240), aaa2340, 2015 | 277 | 2015 |
| Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns MP Schnetz, CF Bartels, K Shastri, D Balasubramanian, GE Zentner, ... Genome research 19 (4), 590-601, 2009 | 261 | 2009 |
| Three classes of genes mutated in colorectal cancers with chromosomal instability Z Wang, JM Cummins, D Shen, DP Cahill, PV Jallepalli, TL Wang, ... Cancer research 64 (9), 2998-3001, 2004 | 259 | 2004 |
| Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation H Lee, P Zhang, A Herrmann, C Yang, H Xin, Z Wang, DSB Hoon, ... Proceedings of the National Academy of Sciences 109 (20), 7765-7769, 2012 | 258 | 2012 |
| Pol κ: a DNA polymerase required for sister chromatid cohesion Z Wang, IB Castano, A De Las Penas, C Adams, MF Christman Science 289 (5480), 774-779, 2000 | 247 | 2000 |
| Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer Y Hao, Y Samuels, Q Li, D Krokowski, BJ Guan, C Wang, Z Jin, B Dong, ... Nature communications 7 (1), 11971, 2016 | 240 | 2016 |
| Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T X Zhang, A Guo, J Yu, A Possemato, Y Chen, W Zheng, RD Polakiewicz, ... Proceedings of the National Academy of Sciences 104 (10), 4060-4064, 2007 | 226 | 2007 |
| DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer CR Merry, ME Forrest, JN Sabers, L Beard, XH Gao, M Hatzoglou, ... Human molecular genetics 24 (21), 6240-6253, 2015 | 176 | 2015 |
| Targeted inactivation of CTNNB1 reveals unexpected effects of β-catenin mutation TA Chan, Z Wang, LH Dang, B Vogelstein, KW Kinzler Proceedings of the National Academy of Sciences 99 (12), 8265-8270, 2002 | 175 | 2002 |
| Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway N Balanis, MK Wendt, BJ Schiemann, Z Wang, WP Schiemann, CR Carlin Journal of Biological Chemistry 288 (25), 17954-17967, 2013 | 150 | 2013 |
| Novel recurrently mutated genes in African American colon cancers K Guda, ML Veigl, V Varadan, A Nosrati, L Ravi, J Lutterbaugh, L Beard, ... Proceedings of the National Academy of Sciences 112 (4), 1149-1154, 2015 | 127 | 2015 |
| Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia X Zhang, AM Saarinen, T Hitosugi, Z Wang, L Wang, TH Ho, J Liu Elife 6, e31132, 2017 | 122 | 2017 |
| Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies X Zhang, C Guo, Y Chen, HP Shulha, MP Schnetz, T LaFramboise, ... Nature methods 5 (2), 163-165, 2008 | 122 | 2008 |
| Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer VWY Lui, ND Peyser, PKS Ng, J Hritz, Y Zeng, Y Lu, H Li, L Wang, ... Proceedings of the National Academy of Sciences 111 (3), 1114-1119, 2014 | 115 | 2014 |
