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Pierre Saintigny, M.D. Ph.D.
Pierre Saintigny, M.D. Ph.D.
Université Claude Bernard Lyon 1 & Centre Léon Bérard
Dirección de correo verificada de lyon.unicancer.fr
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An epithelial–mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor …
LA Byers, L Diao, J Wang, P Saintigny, L Girard, M Peyton, L Shen, Y Fan, ...
Clinical cancer research 19 (1), 279-290, 2013
10032013
Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome
NT Ihle, LA Byers, ES Kim, P Saintigny, JJ Lee, GR Blumenschein, A Tsao, ...
Journal of the National Cancer Institute 104 (3), 228-239, 2012
5572012
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1
LA Byers, J Wang, MB Nilsson, J Fujimoto, P Saintigny, J Yordy, U Giri, ...
Cancer discovery 2 (9), 798-811, 2012
5142012
Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial
J Rodon, JC Soria, R Berger, WH Miller, E Rubin, A Kugel, A Tsimberidou, ...
Nature medicine 25 (5), 751-758, 2019
4292019
New insights into the role of EMT in tumor immune escape
S Terry, P Savagner, S Ortiz‐Cuaran, L Mahjoubi, P Saintigny, JP Thiery, ...
Molecular oncology 11 (7), 824-846, 2017
3812017
miR-200 Inhibits Lung Adenocarcinoma Cell Invasion and Metastasis by Targeting Flt1/VEGFR1
JD Roybal, Y Zang, YH Ahn, Y Yang, DL Gibbons, BN Baird, C Alvarez, ...
Molecular cancer research 9 (1), 25-35, 2011
2312011
CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma
P Saintigny, E Massarelli, S Lin, YH Ahn, Y Chen, S Goswami, B Erez, ...
Cancer research 73 (2), 571-582, 2013
1812013
Recent advances in non-small cell lung cancer biology and clinical management
P Saintigny, JA Burger
Discovery medicine 13 (71), 287-297, 2012
1592012
A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability
AP Morel, C Ginestier, RM Pommier, O Cabaud, E Ruiz, J Wicinski, ...
Nature medicine 23 (5), 568-578, 2017
1582017
Gene expression profiling predicts the development of oral cancer
P Saintigny, L Zhang, YH Fan, AK El-Naggar, VA Papadimitrakopoulou, ...
Cancer Prevention Research 4 (2), 218-229, 2011
1572011
Prognostic and predictive role of CD8 and PD-L1 determination in lung tumor tissue of patients under anti-PD-1 therapy
JD Fumet, C Richard, F Ledys, Q Klopfenstein, P Joubert, B Routy, ...
British journal of cancer 119 (8), 950-960, 2018
1492018
A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers
A Ferrari, A Vincent-Salomon, X Pivot, AS Sertier, E Thomas, L Tonon, ...
Nature communications 7 (1), 12222, 2016
1452016
Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer
M Taoudi Benchekroun, P Saintigny, SM Thomas, AK El-Naggar, ...
Cancer prevention research 3 (7), 800-809, 2010
1422010
Erlotinib and the risk of oral cancer: the erlotinib prevention of oral cancer (EPOC) randomized clinical trial
WN William, V Papadimitrakopoulou, JJ Lee, L Mao, EEW Cohen, HY Lin, ...
JAMA oncology 2 (2), 209-216, 2016
1382016
6 months versus 12 months of adjuvant trastuzumab in early breast cancer (PHARE): final analysis of a multicentre, open-label, phase 3 randomised trial
X Pivot, G Romieu, M Debled, JY Pierga, P Kerbrat, T Bachelot, ...
The Lancet 393 (10191), 2591-2598, 2019
1302019
High mortality rate in cancer patients with symptoms of COVID-19 with or without detectable SARS-COV-2 on RT-PCR
S Assaad, V Avrillon, ML Fournier, B Mastroianni, B Russias, A Swalduz, ...
European Journal of Cancer 135, 251-259, 2020
1242020
Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1α in non-small cell lung cancer cells
L Xu, MB Nilsson, P Saintigny, T Cascone, MH Herynk, Z Du, ...
Oncogene 29 (18), 2616-2627, 2010
1142010
Vascular endothelial growth factor-C and its receptor VEGFR-3 in non-small-cell lung cancer: concurrent expression in cancer cells from primary tumour and metastatic lymph node
P Saintigny, M Kambouchner, M Ly, N Gomes, O Sainte-Catherine, ...
Lung cancer 58 (2), 205-213, 2007
1132007
EZH2 promotes malignant behaviors via cell cycle dysregulation and its mRNA level associates with prognosis of patient with non-small cell lung cancer
W Cao, RO Ribeiro, D Liu, P Saintigny, R Xia, Y Xue, R Lin, L Mao, H Ren
PloS one 7 (12), e52984, 2012
892012
The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 …
JP Foy, C Bertolus, MC Michallet, S Deneuve, R Incitti, ...
Annals of Oncology 28 (8), 1934-1941, 2017
852017
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