Laurent Vallar
Laurent Vallar
Principal Investigator, Luxembourg Institute of Health
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Signatures of microRNAs and selected microRNA target genes in human melanoma
D Philippidou, M Schmitt, D Moser, C Margue, PV Nazarov, A Muller, ...
Cancer research 70 (10), 4163-4173, 2010
Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism
T Farge, E Saland, F de Toni, N Aroua, M Hosseini, R Perry, C Bosc, ...
Cancer discovery 7 (7), 716-735, 2017
Interplay of microRNAs, transcription factors and target genes: linking dynamic expression changes to function
PV Nazarov, SE Reinsbach, A Muller, N Nicot, D Philippidou, L Vallar, ...
Nucleic acids research 41 (5), 2817-2831, 2013
miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers
G Vetter, A Saumet, M Moes, L Vallar, A Le Béchec, C Laurini, M Sabbah, ...
Oncogene 29 (31), 4436-4448, 2010
Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia
A Saumet, G Vetter, M Bouttier, E Portales-Casamar, WW Wasserman, ...
Blood, The Journal of the American Society of Hematology 113 (2), 412-421, 2009
Divalent cations differentially regulate integrin αIIb cytoplasmic tail binding to β3 and to calcium-and integrin-binding protein
L Vallar, C Melchior, S Plançon, H Drobecq, G Lippens, V Regnault, ...
Journal of Biological Chemistry 274 (24), 17257-17266, 1999
Neurodegeneration by activation of the microglial complement–phagosome pathway
LG Bodea, Y Wang, B Linnartz-Gerlach, J Kopatz, L Sinkkonen, ...
Journal of Neuroscience 34 (25), 8546-8556, 2014
A calreticulin‐like molecule from the human hookworm Necator americanus interacts with C1q and the cytoplasmic signalling domains of some integrins
G Kasper, A Brown, M Eberl, L Vallar, N Kieffer, C Berry, K Girdwood, ...
Parasite Immunology 23 (3), 141-152, 2001
Autocrine TGF‐β‐regulated expression of adhesion receptors and integrin‐linked kinase in HT‐144 melanoma cells correlates with their metastatic phenotype
B Janji, C Melchior, V Gouon, L Vallar, N Kieffer
International journal of cancer 83 (2), 255-262, 1999
Sequence and comparative genomic analysis of actin-related proteins
J Muller, Y Oma, L Vallar, E Friederich, O Poch, B Winsor
Molecular biology of the cell 16 (12), 5736-5748, 2005
Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia
E Moussay, V Palissot, L Vallar, HA Poirel, T Wenner, V El Khoury, ...
Molecular cancer 9 (1), 115, 2010
Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes
D Stieber, A Golebiewska, L Evers, E Lenkiewicz, NHC Brons, N Nicot, ...
Acta neuropathologica 127 (2), 203-219, 2014
Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells
A Golebiewska, S Bougnaud, D Stieber, NHC Brons, L Vallar, F Hertel, ...
Brain 136 (5), 1462-1475, 2013
The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom …
E Moussay, T Kaoma, J Baginska, A Muller, K Van Moer, N Nicot, ...
Autophagy 7 (7), 760-770, 2011
Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma
M Sanzey, SAA Rahim, A Oudin, A Dirkse, T Kaoma, L Vallar, ...
PloS one 10 (5), 2015
Elastin-derived peptides increase invasive capacities of lung cancer cells by post-transcriptional regulation of MMP-2 and uPA
S Toupance, B Brassart, F Rabenoelina, C Ghoneim, L Vallar, M Polette, ...
Clinical & experimental metastasis 29 (5), 511-522, 2012
The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs
G Bossis, JE Sarry, C Kifagi, M Ristic, E Saland, F Vergez, T Salem, ...
Cell reports 7 (6), 1815-1823, 2014
Dynamic regulation of microRNA expression following Interferon-γ-induced gene transcription
S Reinsbach, PV Nazarov, D Philippidou, M Schmitt, ...
RNA biology 9 (7), 978-989, 2012
Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer
E Letellier, M Schmitz, K Baig, N Beaume, C Schwartz, S Frasquilho, ...
British journal of cancer 111 (4), 726-735, 2014
RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples
PV Nazarov, A Muller, T Kaoma, N Nicot, C Maximo, P Birembaut, ...
BMC genomics 18 (1), 443, 2017
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