Ranjith R Ramesh
Ranjith R Ramesh
Sunnybrook Health Sciences Center
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Synthesis, antiviral potency, in vitro ADMET, and X-ray structure of potent CD4 mimics as entry inhibitors that target the Phe43 cavity of HIV-1 gp120
F Curreli, YD Kwon, DS Belov, RR Ramesh, AV Kurkin, A Altieri, ...
Journal of medicinal chemistry 60 (7), 3124-3153, 2017
Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120
F Curreli, DS Belov, Y Do Kwon, R Ramesh, AM Furimsky, K O'Loughlin, ...
European journal of medicinal chemistry 154, 367-391, 2018
Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity
F Curreli, DS Belov, RR Ramesh, N Patel, A Altieri, AV Kurkin, ...
Bioorganic & medicinal chemistry 24 (22), 5988-6003, 2016
Synthesis, Antiviral Activity, and Structure–Activity Relationship of 1, 3‐Benzodioxolyl Pyrrole‐Based Entry Inhibitors Targeting the Phe43 Cavity in HIV‐1 gp120
F Curreli, DS Belov, S Ahmed, RR Ramesh, AV Kurkin, A Altieri, ...
ChemMedChem 13 (21), 2332-2348, 2018
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